Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Hiroyuki Sugiuchi"'
Autor:
Kazumi Matsushima-Nagata, Takeshi Matsumura, Yuki Kondo, Kensaku Anraku, Kazuki Fukuda, Mikihiro Yamanaka, Masahiro Manabe, Tetsumi Irie, Eiichi Araki, Hiroyuki Sugiuchi
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 468 (2023)
Remnant lipoproteins (RLs), which are typically present at high concentrations in patients with type 2 diabetes mellitus (T2DM), are associated with cardiovascular disease (CVD). Although an RL cholesterol homogeneous assay (RemL-C) is available for
Externí odkaz:
https://doaj.org/article/e5bceaec729947bfb818d6b31e873879
Autor:
Rui Yamaguchi, Arisa Sakamoto, Reona Yamaguchi, Misa Haraguchi, Shinji Narahara, Hiroyuki Sugiuchi, Yasuo Yamaguch
Publikováno v:
Heliyon, Vol 8, Iss 2, Pp e08887- (2022)
The IL-23/IL-17 axis plays an important role in the development of autoimmune diseases, but the mechanism regulating IL-23 production is mainly unknown. We investigated how TNFAIP3 and Sp1 affect IL-23 production by human macrophages after exposure t
Externí odkaz:
https://doaj.org/article/17eb04abd7174d77ab8a8caf6c61edec
Autor:
Arisa Sakamoto, Rui Yamaguchi, Reona Yamaguchi, Shinji Narahara, Hiroyuki Sugiuchi, Yasuo Yamaguchi
Publikováno v:
Heliyon, Vol 4, Iss 7, Pp e00679- (2018)
RANTES is a key chemokine for atherosclerosis, and obesity is associated with progression of atherosclerosis. Substance P (SP) increases glucose uptake and accumulation of lipids in adipocytes, and SP may upregulate RANTES expression. This study inve
Externí odkaz:
https://doaj.org/article/16272a6820754074a4f414b4b8db5b9d
Autor:
Rui Yamaguchi, Takatoshi Yamamoto, Arisa Sakamoto, Yasuji Ishimaru, Shinji Narahara, Hiroyuki Sugiuchi, Yasuo Yamaguchi
Publikováno v:
Heliyon, Vol 2, Iss 2 (2016)
Interferon (IFN)-gamma is highly expressed in atherosclerotic lesions and may have an important role in atherogenesis. Myeloperoxidase (MPO), the most abundant protein in neutrophils, is a marker of plaque vulnerability and a possible bridge between
Externí odkaz:
https://doaj.org/article/7ccd26c52873492aa51a698316915d6b
Autor:
Arisa Sakamoto, Shinji Narahara, Takahiko Katoh, Hiroyuki Sugiuchi, Rui Yamaguchi, Yasuo Yamaguchi, Misa Haraguchi, Reona Yamaguchi
Publikováno v:
The American Journal of the Medical Sciences. 357:492-506
Background Plasminogen activator inhibitor type 1 promotes formation of endothelial microparticles with procoagulant activity. However, it remains unclear whether di-(2-ethylhexyl) phthalate, a peroxisome proliferator-activated receptor α agonist, i
Autor:
Arisa Sakamoto, Rui Yamaguchi, Yasuo Yamaguchi, Shinji Narahara, Reona Yamaguchi, Hiroyuki Sugiuchi, Misa Haraguchi
Publikováno v:
Journal of Cellular Signaling. 2
Autor:
Yuki Katayama, Mizuki Sumida, Norihiko Kayahara, Takako Takao, Yuki Kondo, Eiichi Araki, Yoichi Ishitsuka, Mitsuru Irikura, Tetsumi Irie, Kazumi Matsushima-Nagata, Hiroyuki Sugiuchi, Kensaku Anraku, Takeshi Matsumura
Publikováno v:
Analytical biochemistry. 613
Existing methods to measure high-density lipoprotein cholesterol (HDL-C) subclasses (HDL2-C and HDL3-C) are complex and require proficiency, and thus there is a need for a convenient, homogeneous assay to determine HDL-C subclasses in serum. Here, ch
Autor:
Shinji Narahara, Rui Yamaguchi, Yasuo Yamaguchi, Arisa Sakamoto, Misa Haraguchi, Reona Yamaguchi, Hiroyuki Sugiuchi
Publikováno v:
Cytokine. 134
The chemokine fractalkine is synthesized as a membrane-bound protein, but studies have shown that serum levels of soluble fractalkine are elevated in inflammatory and autoimmune diseases. Patients with autoimmune diseases also have increased serum le
Autor:
Shinji Narahara, Yasuo Yamaguchi, Takatoshi Yamamoto, Rui Yamaguchi, Hiroyuki Sugiuchi, Arisa Sakamoto
Publikováno v:
Cytokine. 99:310-315
Cross-talks between toll-like receptors (TLRs) including various negative regulatory mechanisms are many unknown. We investigated the differential mechanism of IL-23 production in M1 macrophages by single immunoglobulin interleukin-1 receptor-related
Autor:
Yasuo Yamaguchi, Arisa Sakamoto, Shinji Narahara, Hiroyuki Sugiuchi, Rui Yamaguchi, Takatoshi Yamamoto
Publikováno v:
Blood Cells, Molecules, and Diseases. 59:1-7
Proteinase-activated receptor 2 (PAR-2) and toll-like receptor 4 (TLR4) are involved in innate immune responses and signaling cross-talk between these receptor molecules has the potential to augment an ongoing inflammatory response. The aim of this s