Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hiroyuki Shiina"'
Autor:
Yoshioki Satoh, Akira Takahara, Keitaro Hashimoto, Hiroyuki Shiina, Atsushi Sugiyama, Masahiko Yoneyama
Publikováno v:
Journal of Cardiovascular Pharmacology. 38:940-946
Summary: A recent in vitro study demonstrated that supratherapeutic concentrations of sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, blocked I Kr and prolonged cardiac repolarization. This study assessed the in vivo cardiohemodynamic and el
Publikováno v:
Toxicology and Applied Pharmacology. 169:8-16
Drug-induced prolongation of the QT interval is often associated with the onset of Torsades de Pointes (TdP) resulting in a life-threatening ventricular arrhythmia. The potential of the proarrhythmic effects of the new fluoroquinolone antibacterial a
Publikováno v:
Japanese Circulation Journal. 64:777-782
The cardiovascular profile of verapamil was assessed in the halothane-anesthetized canine model and compared with that of propranolol. Verapamil was infused at the rates of 1, 3 and 10 microg x kg(-1) x min(-1) (n=6), whereas propranolol was administ
Autor:
Masakazu Aruga, Seiichi Furuta, Yasuyuki Sasaki, Syouji Sawaki, Kazuhiro Suyama, Hiroyuki Shiina, Yuuichi Katagiri, Ryuuichi Sakai, Masaaki Nagasaki
Publikováno v:
Japanese Journal of Electrocardiology. 17:70-77
症例は66歳女性.17歳の第1子出産時に初めて動悸発作を自覚.S56年心電図にてWPW症候群と診断され近医にてジソピラミドの投与を受けるようになったが, 発作頻度は不変で緊急外来を受診し
Publikováno v:
Journal of cardiovascular pharmacology. 40(2)
A patient had QT prolongation and syncope after starting sulpiride therapy. The present experiments were performed to clarify the causal link among the sulpiride administration, QT prolongation, and the onset of torsade de pointes. Two in vivo models
Autor:
Fumio Kurogouchi, Toyohisa Miyashita, Yuuichi Katagiri, Tatsuya Usui, Jin Kamiya, Hiroyuki Shiina, Kendo Kiyosawa, Manabu Takei, Takeshi Tomita
Publikováno v:
Echocardiography (Mount Kisco, N.Y.). 18(3)
Publikováno v:
JOURNAL OF THE ILLUMINATING ENGINEERING INSTITUTE OF JAPAN. 86:122-122
Publikováno v:
Japanese Journal of Pharmacology. 82:117