Zobrazeno 1 - 10
of 559
pro vyhledávání: '"Hiroyuki Shibata"'
Autor:
Hiroo Imai, Yasuhiro Sakamoto, Shin Takahashi, Hiroyuki Shibata, Atsushi Sato, Kazunori Otsuka, Kenji Amagai, Masanobu Takahashi, Takuhiro Yamaguchi, Chikashi Ishioka
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Advanced pancreatic cancer is one of the leading causes of cancer-related deaths. For patients with advanced pancreatic cancer, gemcitabine and nanoparticle albumin-binding paclitaxel (nabPTX) combination (GEM/nabPTX) therapy is o
Externí odkaz:
https://doaj.org/article/5310443217344e7f9c587dac657eb026
Clinical Course of a Rare Epstein-Barr Virus-Associated Smooth Muscle Tumor and Its Genomic Analysis
Autor:
Jun Miyahara, Kazuhiro Shimazu, Ayano Saito, Mitsuru Saito, Koji Fukuda, Taichi Yoshida, Daiki Taguchi, Hanae Shinozaki, Naoto Takahashi, Hiroshi Nanjyo, Hiroyuki Shibata
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 571-578 (2023)
Epstein-Barr virus (EBV) can rarely induce smooth muscle tumors (SMTs). A 20-year-old female patient underwent kidney transplantation for renal failure. Since then, she has been treated with immunosuppressants, including a calcineurin inhibitor, tacr
Externí odkaz:
https://doaj.org/article/1bbf581345e44f00906a97a9c751974c
Autor:
Hidekazu Shirota, Keigo Komine, Masanobu Takahashi, Shin Takahashi, Eisaku Miyauchi, Hidetaka Niizuma, Hiroshi Tada, Muneaki Shimada, Tetsuya Niihori, Yoko Aoki, Ikuko Sugiyama, Maako Kawamura, Jun Yasuda, Shuhei Suzuki, Takeshi Iwaya, Motonobu Saito, Tsuyoshi Saito, Hiroyuki Shibata, Toru Furukawa, Chikashi Ishioka
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 6170-6181 (2023)
Abstract Background A paradigm shift has occurred in cancer chemotherapy from tumor‐specific treatment with cytotoxic agents to personalized medicine with molecular‐targeted drugs. Thus, it is essential to identify genomic alterations and molecul
Externí odkaz:
https://doaj.org/article/8a80aeda87b14dc480de839989bfda14
Autor:
Maya Suzuki, Yohei Yamamoto, Aki Nishijima‐Matsunobu, Yohei Kawasaki, Hiroyuki Shibata, Yasufumi Omori
Publikováno v:
FEBS Open Bio, Vol 13, Iss 3, Pp 434-446 (2023)
Cancer stem cells (CSCs) are proposed to be involved in tumor initiation and play important roles in cancer relapse, metastasis, and drug resistance. Therefore, the targeting of CSCs has potential for effective anticancer therapies. Curcumin is one o
Externí odkaz:
https://doaj.org/article/e9e75b2c3d64458590f62a9eb182e41b
Autor:
Yue Mounai, Taichi Yoshida, Shogo Ito, Koji Fukuda, Kazuhiro Shimazu, Daiki Taguchi, Hanae Shinozaki, Daichi Takagi, Kazuhiro Imai, Hiroshi Yamamoto, Yoshihiro Minamiya, Hiroshi Nanjyo, Hiroyuki Shibata
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 21-29 (2023)
Intimal sarcoma is an extremely rare mesenchymal tumor arising in the great vessels. To date, intimal sarcoma has not been reported in patients with Lynch syndrome (LS), even though this syndrome lacks DNA mismatch repair ability genetically and is p
Externí odkaz:
https://doaj.org/article/525f9e2b00d04ddda3a9d82597fef936
Autor:
Takashi MaruYama, Hirofumi Miyazaki, Yun-Ji Lim, Jian Gu, Masaki Ishikawa, Taichi Yoshida, WanJun Chen, Yuji Owada, Hiroyuki Shibata
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Pyrolyzed deketene curcumin GO-Y022 prevents carcinogenesis in a gastric cancer mouse model. However, it is still less clear if GO-Y022 affects tumor-induced immune suppression. In this study, we found that GO-Y022 inhibited Treg generation in the pr
Externí odkaz:
https://doaj.org/article/f7013cfc9de84921832b3b6046d45e8f
Autor:
Yoriko Kato, Kazuhiro Shimazu, Koji Fukuda, Taichi Yoshida, Daiki Taguchi, Hanae Shinozaki, Hiroshi Nanjyo, Hiroyuki Shibata
Publikováno v:
Case Reports in Oncology, Vol 15, Iss 1, Pp 21-26 (2022)
Cancer of unknown primary (CUP) accounts for 5% of all malignancies. Patients with CUP may live averagely for 8 months after diagnosis, and thus, rapid and reasonable diagnosis is necessary. Among patients with CUP, anaplastic lymphoma kinase (ALK)-o
Externí odkaz:
https://doaj.org/article/9528bc58020b4e11a6003518e0e0adf4
Autor:
Yean Sheng Lee, Xinyue Chen, Tria Widiasih Widiyanto, Kanami Orihara, Hiroyuki Shibata, Susumu Kajiwara
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Candida albicans is a pathogenic yeast that causes candidiasis in immunocompromised patients. The overuse of antifungal drugs has led to the development of resistance to such drugs by this fungus, which is a major challenge in antifungal chemotherapy
Externí odkaz:
https://doaj.org/article/015159e6109843a48b570a0e9add5703
Autor:
Shinogu Takashima, Kazuhiro Imai, Maiko Atari, Tsubasa Matsuo, Katsutoshi Nakayama, Yusuke Sato, Satoru Motoyama, Hiroyuki Shibata, Kyoko Nomura, Yoshihiro Minamiya
Publikováno v:
World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Purpose In cases of non-small cell lung cancer (NSCLC), surgery remains the best option for cure, but surgery is of benefit only when the disease is localized. Although adjuvant chemotherapy reportedly has a significant beneficial effect on
Externí odkaz:
https://doaj.org/article/256ef5af85644651a9701896c74a2113
Autor:
Yu Oishi, Harshana Habaragamuwa, Yu Zhang, Ryo Sugiura, Kenji Asano, Kotaro Akai, Hiroyuki Shibata, Taketo Fujimoto
Publikováno v:
International Journal of Applied Earth Observations and Geoinformation, Vol 104, Iss , Pp 102509- (2021)
Potatoes are the world’s most important root and tuber crop. A diseased seed potato can produce approximately 10 potato tubers, and the disease can propagate through the seed potato production cycle. To promote stable potato production, quality see
Externí odkaz:
https://doaj.org/article/08822b9c204d4ec695bc59d6dd123a01