Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hiroyuki Satofuka"'
Autor:
Hiroyuki Satofuka, Yayan Wang, Hiroshi Tanaka, Kei Hiramatsu, Kayoko Morimoto, Haruka Takayama, Haochen Tu, Yu Qiao, Satoru Ito, Xu Gao, Mitsuo Oshimura, Yasuhiro Kazuki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The antigen-mediated B cell isolation method, based on the detection of surface IgG (sIgG), has increased the efficiency of therapeutic antibody (Ab) discovery. However, the reduction in sIgG expression on B cells during plasma cell differen
Externí odkaz:
https://doaj.org/article/d15efea2b58f43679653c63cc70b1a86
Autor:
Narumi Uno, Hiroyuki Satofuka, Hitomaru Miyamoto, Kazuhisa Honma, Teruhiko Suzuki, Kyotaro Yamazaki, Ryota Ito, Takashi Moriwaki, Shusei Hamamichi, Kazuma Tomizuka, Mitsuo Oshimura, Yasuhiro Kazuki
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 391-403 (2023)
Microcell-mediated chromosome transfer is an attractive technique for transferring chromosomes from donor cells to recipient cells and has enabled the generation of cell lines and humanized animal models that contain megabase-sized gene(s). However,
Externí odkaz:
https://doaj.org/article/6a1d3237830545f0abde19627d69f0ec
Autor:
Hiroyuki Satofuka, Yayan Wang, Kyotaro Yamazaki, Shusei Hamamichi, Takeshi Fukuhara, Abdur Rafique, Nana Osako, Iori Kanazawa, Takeshi Endo, Naomi Miyake, Kazuhisa Honma, Yuichi Nagashima, Genki Hichiwa, Kazuto Shimoya, Satoshi Abe, Takashi Moriwaki, Yasufumi Murakami, Xu Gao, Hiroyuki Kugoh, Mitsuo Oshimura, Yuji Ito, Yasuhiro Kazuki
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract We previously generated fully human antibody-producing TC-mAb mice for obtaining potential therapeutic monoclonal antibodies (mAbs). In this study, we investigated 377 clones of fully human mAbs against a tumor antigen, epithelial cell adhes
Externí odkaz:
https://doaj.org/article/fb5f52237457428e8d9321f244d2301d
Autor:
Hiroyuki Satofuka, Satoshi Abe, Takashi Moriwaki, Akane Okada, Kanako Kazuki, Hiroshi Tanaka, Kyotaro Yamazaki, Genki Hichiwa, Kayoko Morimoto, Haruka Takayama, Yuji Nakayama, Shinya Hatano, Yutaro Yada, Yasufumi Murakami, Yoshihiro Baba, Mitsuo Oshimura, Kazuma Tomizuka, Yasuhiro Kazuki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Trans-chromosomic (Tc) mice have helped the development of therapeutic antibodies, but chromosome instability limits its application. Here the authors develop a new line of Tc mice with full human Ig heavy and kappa loci integrated into the mouse art
Externí odkaz:
https://doaj.org/article/fb7ca36c22fa4c8995612d2e3884ca5e
Autor:
Keisuke Goto, Mitsuhiko Osaki, Runa Izutsu, Hiroshi Tanaka, Ryo Sasaki, Akimitsu Tanio, Hiroyuki Satofuka, Yasuhiro Kazuki, Manabu Yamamoto, Hiroyuki Kugoh, Hisao Ito, Mitsuo Oshimura, Yoshiyuki Fujiwara, Futoshi Okada
Publikováno v:
Diagnostic Pathology, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Instruction The human amphoterin-induced gene and open reading frame (AMIGO) was identified as a novel cell adhesion molecule of type I transmembrane protein. AMIGO2 is one of three members of the AMIGO family (AMIGO1, 2, and 3), and the sim
Externí odkaz:
https://doaj.org/article/9ad41b48f36f47758a608cc7a4b8266f
Autor:
Ryo Sasaki, Yasuhiro Kazuki, Hiroyuki Satofuka, Runa Izutsu, Keisuke Goto, Futoshi Okada, Akimitsu Tanio, Hiroshi Tanaka, Mitsuo Oshimura, Yoshiyuki Fujiwara, Hisao Ito, Mitsuhiko Osaki, Hiroyuki Kugoh, Manabu Yamamoto
Publikováno v:
Diagnostic Pathology
Diagnostic Pathology, Vol 17, Iss 1, Pp 1-12 (2022)
Diagnostic Pathology, Vol 17, Iss 1, Pp 1-12 (2022)
Instruction The human amphoterin-induced gene and open reading frame (AMIGO) was identified as a novel cell adhesion molecule of type I transmembrane protein. AMIGO2 is one of three members of the AMIGO family (AMIGO1, 2, and 3), and the similarity b
Autor:
Genki Hichiwa, Akane Okada, Kazuma Tomizuka, Yasuhiro Kazuki, Kanako Kazuki, Hiroyuki Satofuka, Satoshi Abe, Yuji Nakayama, Mitsuo Oshimura, Haruka Takayama, Shinya Hatano, Kayoko Morimoto, Kyoutarou Yamazaki, Takashi Moriwaki, Yoshihiro Baba, Hiroshi Tanaka
Trans-chromosomic (Tc) mice carrying mini-chromosomes with human immunoglobulin (Ig) loci have contributed to the development of fully human therapeutic monoclonal antibodies (Abs); however, we previously observed that mitotic instability of human mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec062685390783562035a4d4e10f185c
https://doi.org/10.21203/rs.3.rs-103241/v1
https://doi.org/10.21203/rs.3.rs-103241/v1
Autor:
Shunsuke Kita, Shuhei Sakakibara, Taishi Onodera, Shuetsu Fukushi, Hiroyuki Satofuka, Takashi Tadokoro, Akihiko Sato, Hideo Fukuhara, Cong Tian, Kohei Yumoto, Jiei Sasaki, Yoshiharu Matsuura, Yasuhiro Kazuki, Yuki Anraku, Katsumi Maenaka, Noriyo Nagata, Hirofumi Sawa, Yasuko Orba, Takao Nomura, Tomohiro Kurosaki, Tadaki Suzuki, Tateki Suzuki, Yu Adachi, Saya Moriyama, Yoshimasa Takahashi, Nozomi Shiwa, Tsuyoshi Sekizuka, Makoto Kuroda, Takeshi Inoue, Lin Sun, Naoko Iwata, Mitsuo Oshimura, Takao Hashiguchi, Keisuke Tonouchi, Michihito Sasaki
Publikováno v:
Immunity
Potently neutralizing SARS-CoV-2 antibodies often target the spike protein receptor binding site (RBS), but the variability of RBS epitopes hampers broad neutralization of multiple sarbecoviruses and drifted viruses. Here, using humanized mice, we id
Publikováno v:
Biochemical and Biophysical Research Communications. 450:99-104
A novel method using metastatic breast cancer cell lines was established for producing monoclonal antibodies (mAbs) against multi-span membrane proteins. Grafting of metastatic cells (MCF7-14) into the mammary gland of BALB/cJ/nu/nu mice induced sple
Autor:
Yutaka Eguchi, Satoshi Amano, Kazuhisa Miyamoto, Hiroyuki Satofuka, Masahiro Takagi, Kazumasa Hirata, Haruo Mizuno, Tadayuki Imanaka, Kiichi Fukui
Publikováno v:
JOURNAL OF BIOCHEMISTRY. 131(2):233-239
The apoptotic cell death of Jurkat cells due to Cd 2 + toxicity was studied by fluorescence microscopic observation and DNA fragmentation assaying. It was suggested that the apoptotic response to Cd 2 + was less clear than that to a typical apoptosis