Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hiroyuki Nagaretani"'
Autor:
Masako Waki, Kensuke Fukui, Hiroyuki Nagaretani, Tohru Funahashi, Ken Kishida, Yuji Matsuzawa, Norikazu Maeda, Shinji Kihara, Azumi Nagasawa, Toshiyuki Hibuse, Hitoshi Nishizawa, Kiyoharu Takamatsu, Makiko Kojima
Publikováno v:
Biochemical and Biophysical Research Communications. 311:909-914
Adipose tissue secretes various bioactive molecules called adipocytokines. Dysregulation of adipocytokines plays an important role in the development of atherosclerotic vascular diseases. Consumption of vegetable protein reduces the risks of atherosc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4b2c39278c34ec6c1d7cb7313f9287
https://doi.org/10.1016/j.bbrc.2003.10.087
https://doi.org/10.1016/j.bbrc.2003.10.087
Autor:
Ken Kishida, Yuji Matsuzawa, Tohru Funahashi, Norikazu Maeda, Yoshihisa Okamoto, Ryozo Nagai, Noriyuki Ouchi, Makoto Nishida, Ryutaro Komuro, Yukio Arita, Masataka Sata, Morihiro Matsuda, Shinji Kihara, Masahiro Kumada, Hitoshi Nishizawa, Iichiro Shimomura, Hiroyuki Nagaretani
Publikováno v:
Journal of Biological Chemistry. 277:37487-37491
Obesity is more linked to vascular disease, including atherosclerosis and restenotic change, after balloon angioplasty. The precise mechanism linking obesity and vascular disease is still unclear. Previously we have demonstrated that the plasma level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c13644ecefac73181be59fb22a045fe
https://doi.org/10.1074/jbc.m206083200
https://doi.org/10.1074/jbc.m206083200
Autor:
Hidehiko Kondo, Ken Kishida, Yuji Matsuzawa, Yoshihiro Tochino, Shinji Kihara, Hiroyuki Nagaretani, Hiroshi Kuriyama, Norikazu Maeda, Morihiro Matsuda, Tohru Funahashi, Tadashi Nakamura, Naoki Furuyama, Hitoshi Nishizawa, Iichiro Shimomura
Publikováno v:
Diabetes. 51:2734-2741
Adiponectin, an adipose-specific secretory protein, exhibits antidiabetic and antiatherogenic properties. In the present study, we examined the effects of sex hormones on the regulation of adiponectin production. Plasma adiponectin concentrations wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c889a765acdcab7f58f8d512e5508f9
https://doi.org/10.2337/diabetes.51.9.2734
https://doi.org/10.2337/diabetes.51.9.2734
Autor:
Norikazu Maeda, Hitoshi Nishizawa, Iichiro Shimomura, Satoshi Takeda, Masato Horie, Hidehiko Kondo, Keiichi Okutomi, Ken Kishida, Yuji Matsuzawa, Masahiko Takahashi, Morihiro Matsuda, Tohru Funahashi, Naoki Furuyama, Yukio Arita, Noriyuki Ouchi, Yoshihiro Tochino, Shinji Kihara, Toshifumi Aoyama, Hiroyuki Nagaretani, Ryutaro Komuro
Publikováno v:
Nature Medicine. 8:731-737
Here we investigated the biological functions of adiponectin/ACRP30, a fat-derived hormone, by disrupting the gene that encodes it in mice. Adiponectin/ACRP30-knockout (KO) mice showed delayed clearance of free fatty acid in plasma, low levels of fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92648d29ab0fc00b5102d11d508ff99
https://doi.org/10.1038/nm724
https://doi.org/10.1038/nm724
Autor:
Tohru Funahashi, Hiroyuki Nagaretani, Hidehiko Kondo, Ken Kishida, Yuji Matsuzawa, Norikazu Maeda, Kikuko Hotta, Hiroshi Kuriyama, Hitoshi Nishizawa, Noriyuki Ouchi, Shinji Kihara, Iichiro Shimomura, Morihiro Matsuda, Takashi Kadowaki
Publikováno v:
Europe PubMed Central
The current study demonstrates that aquaporin adipose (AQPap), an adipose-specific glycerol channel (Kishida, K., Kuriyama, H., Funahashi, T., Shimomura, I., Kihara, S., Ouchi, N., Nishida, M., Nishizawa, H., Matsuda, M., Takahashi, M., Hotta, K., Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60e57a63be0a657129ab28141ff28f0e
https://doi.org/10.1074/jbc.m108213200
https://doi.org/10.1074/jbc.m108213200
Autor:
Yoshihiro Kamada, Hiroyuki Nagaretani, Shinji Tamura, Tohru Ohama, Takao Maruyama, Hisatoyo Hiraoka, Shizuya Yamashita, Akira Yamada, Shinichi Kiso, Yoshiaki Inui, Nobuyuki Ito, Yoshiro Kayanoki, Sumio Kawata, Yuji Matsuzawa
Publikováno v:
Journal of Clinical Investigation. 108:717-724
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10b4ea2cd8562d6baf3cba99f350cde2
https://doi.org/10.1172/jci200111260
https://doi.org/10.1172/jci200111260
Autor:
Hiroshi Kuriyama, Kikuko Hotta, Ken Kishida, Yuji Matsuzawa, Hitoshi Nishizawa, Shizuya Yamashita, Tohru Funahashi, Iichiro Shimomura, Noriyuki Ouchi, Kazuhisa Maeda, Masahiko Takahashi, Norikazu Maeda, Hiroyuki Nagaretani, Tadashi Nakamura, Shinji Kihara
Publikováno v:
Obesity Research. 9:388-393
Objective: Adipocytes secrete various cytokines and matrix proteins. Several of them precipitate in obesity-associated diseases, including atherosclerosis. In the current study, we have examined the expression of secreted protein, acidic and rich in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6046fda11c8bcc1cade5d4d018354f21
https://doi.org/10.1038/oby.2001.50
https://doi.org/10.1038/oby.2001.50
Autor:
Ken Kishida, Yuji Matsuzawa, Hiroyuki Nagaretani, Noriyuki Ouchi, Tohru Funahashi, Koji Ohashi, Kazuhisa Maeda, Masahiro Kumada, Shinji Kihara, Hideki Kobayashi, Yoshihisa Okamoto, Azumi Nagasawa, Norikazu Maeda
Publikováno v:
Circulation. 109(17)
Background— Vascular inflammation and subsequent matrix degradation play an important role in the development of atherosclerosis. We previously reported that adiponectin, an adipose-specific plasma protein, accumulated to the injured artery and att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6819159431c7c351c740bdbde9a6d6
https://pubmed.ncbi.nlm.nih.gov/15096450
https://pubmed.ncbi.nlm.nih.gov/15096450
Autor:
Noriyuki Ouchi, Koji Ohashi, Hideki Kobayashi, Masahiro Kumada, Norio Komai, Hiroyuki Nagaretani, Tohru Funahashi, Tadashi Nakamura, Hisatoyo Hiraoka, Azumi Nagasawa, Masaharu Kaibe, Hiromi Rakugi, Norikazu Maeda, Shinji Kihara, Toshio Ogihara, Yoshihisa Okamoto, Hitoshi Nishizawa, Mitsuru Ohishi, Ken Kishida, Yuji Matsuzawa
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 42(3)
Endothelial dysfunction is a crucial feature in the evolution of atherosclerosis. Adiponectin is an adipocyte-specific plasma protein with antiatherogenic and antidiabetic properties. In the present study, we investigated the relation between adipone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c796b491ff5e9d0e7a8a28091f54cb6c
https://pubmed.ncbi.nlm.nih.gov/12860835
https://pubmed.ncbi.nlm.nih.gov/12860835
Autor:
Tohru Funahashi, Hideki Kobayashi, Azumi Nagasawa, Sachiyo Tanaka, Masahiro Kumada, Hidehiko Kondo, Koji Ohashi, Ken Kishida, Yuji Matsuzawa, Kazuhisa Maeda, Shinji Kihara, Toshiyuki Hibuse, Hitoshi Nishizawa, Norikazu Maeda, Noriyuki Ouchi, Hiroyuki Nagaretani, Yoshihisa Okamoto
Publikováno v:
Biochemical and biophysical research communications. 306(1)
Adiponectin, an adipocyte-derived protein, consists of collagen-like fibrous and complement C1q-like globular domains, and circulates in human plasma in a multimeric form. The protein exhibits anti-diabetic and anti-atherogenic activities. However, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f0639f585c7bdb36467b0d27122175
https://pubmed.ncbi.nlm.nih.gov/12788102
https://pubmed.ncbi.nlm.nih.gov/12788102