Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hiroyuki Miyo"'
Publikováno v:
Journal of Medical Cases
In a 75-year-old hemodialysis patient, pneumonia manifested with computed tomography (CT) images suggestive of coronavirus disease 2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) was not detected w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a15b3fbf198b9de723707068cfcb2d
https://doi.org/10.14740/jmc3566
https://doi.org/10.14740/jmc3566
Autor:
Yuki Aisu, Nobu Oshima, Fuminori Hyodo, Abdelazim Elsayed Elhelaly, Akihiko Masuo, Tomoaki Okada, Shigeo Hisamori, Shigeru Tsunoda, Koya Hida, Tomonori Morimoto, Hiroyuki Miyoshi, Makoto M Taketo, Masayuki Matsuo, Leonard M Neckers, Yoshiharu Sakai, Kazutaka Obama
Publikováno v:
PLoS ONE, Vol 19, Iss 12, p e0309700 (2024)
Pyruvate is situated at the intersection of oxidative phosphorylation (OXPHOS) and glycolysis, which are the primary energy-producing pathways in cells. Cancer therapies targeting these pathways have been previously documented, indicating that inhibi
Externí odkaz:
https://doaj.org/article/e6f1c773e575447aaf8ece3fe500cb4a
Autor:
Ryota Tamura, Hiroyuki Miyoshi, Kent Imaizumi, Masahiro Yo, Yoshitaka Kase, Tsukika Sato, Mizuto Sato, Yukina Morimoto, Oltea Sampetrean, Jun Kohyama, Munehisa Shinozaki, Atsushi Miyawaki, Kazunari Yoshida, Hideyuki Saya, Hideyuki Okano, Masahiro Toda
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 5, Pp n/a-n/a (2023)
Abstract Glioblastoma is characterized by diffuse infiltration into the normal brain. Invasive glioma stem cells (GSCs) are an underlying cause of treatment failure. Despite the use of multimodal therapies, the prognosis remains dismal. New therapeut
Externí odkaz:
https://doaj.org/article/f4a584e8ee4f40d1bbb274fb47a70344
Autor:
Takeshi Ito, Yohei Kawai, Yutaka Yasui, Shoichi Iriguchi, Atsutaka Minagawa, Tomoko Ishii, Hiroyuki Miyoshi, M. Mark Taketo, Kenji Kawada, Kazutaka Obama, Yoshiharu Sakai, Shin Kaneko
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Ito et al. generated and characterized multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-derived iPS cells (TIL-iPSC) using human colorectal cancer specimens. They demonstrated that the newly-generated T cells retained intrin
Externí odkaz:
https://doaj.org/article/aae603ed56fd496c983a89c36cc8f3f1
Autor:
Gen Nishikawa, Kenji Kawada, Keita Hanada, Hisatsugu Maekawa, Yoshiro Itatani, Hiroyuki Miyoshi, Makoto Mark Taketo, Kazutaka Obama
Publikováno v:
Cells, Vol 11, Iss 20, p 3273 (2022)
Reprogramming of energy metabolism is regarded as one of the hallmarks of cancer; in particular, oncogenic RAS has been shown to be a critical regulator of cancer metabolism. Recently, asparagine metabolism has been heavily investigated as a novel ta
Externí odkaz:
https://doaj.org/article/757cb1963f1144f6881106a3e0ecaf2f
Autor:
Ryota Tamura, Hiroyuki Miyoshi, Oltea Sampetrean, Munehisa Shinozaki, Yukina Morimoto, Chizuru Iwasawa, Raita Fukaya, Yutaka Mine, Hirotaka Masuda, Tetsuo Maruyama, Minoru Narita, Hideyuki Saya, Kazunari Yoshida, Hideyuki Okano, Masahiro Toda
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-10 (2019)
Abstract Glioblastoma exhibits phenotypic and genetic heterogeneity, aggressive invasiveness, therapeutic resistance, and tumor recurrence, which can be explained by the existence of glioma stem cells (GSCs). In this study, we visualized the spatiote
Externí odkaz:
https://doaj.org/article/b28eb4eb9715437ea41904cdee4f5d83
Publikováno v:
SICE Journal of Control, Measurement, and System Integration, Vol 11, Iss 6, Pp 470-476 (2018)
Nondestructive inspection of the sizes and positions of defect regions in a fuel cell is an indispensable task in order to ensure their practical use. In the present paper, a level set method for estimating the defects in a membrane electrode assembl
Externí odkaz:
https://doaj.org/article/7e0609783fc94404a036bfe562d2a343
Autor:
Go Itakura, Soya Kawabata, Miki Ando, Yuichiro Nishiyama, Keiko Sugai, Masahiro Ozaki, Tsuyoshi Iida, Toshiki Ookubo, Kota Kojima, Rei Kashiwagi, Kaori Yasutake, Hiromitsu Nakauchi, Hiroyuki Miyoshi, Narihito Nagoshi, Jun Kohyama, Akio Iwanami, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 673-684 (2017)
Human induced pluripotent stem cells (iPSCs) are promising in regenerative medicine. However, the risks of teratoma formation and the overgrowth of the transplanted cells continue to be major hurdles that must be overcome. Here, we examined the effic
Externí odkaz:
https://doaj.org/article/668d828c99c0461a96ad761bc1e5fc40
Publikováno v:
Cells, Vol 10, Iss 2, p 256 (2021)
Humans with biallelic inactivating mutations in Epithelial Cell Adhesion Molecule (EpCAM) develop congenital tufting enteropathy (CTE). To gain mechanistic insights regarding EpCAM function in this disorder, we prepared intestinal epithelial cell (IE
Externí odkaz:
https://doaj.org/article/66acaa9e1e6642ef89a9a820d9ab6d46
Autor:
Junji Koya, Keisuke Kataoka, Tomohiko Sato, Masashige Bando, Yuki Kato, Takako Tsuruta-Kishino, Hiroshi Kobayashi, Kensuke Narukawa, Hiroyuki Miyoshi, Katsuhiko Shirahige, Mineo Kurokawa
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
DNMT3A mutations are known to cause acute myeloid leukaemia. Here, Koya et al. show that DNMT3A R882H mutation causes monoblastic transformation and haematopoietic stem cell accumulation in a methylation-independent manner, by suppressing the polycom
Externí odkaz:
https://doaj.org/article/3b5a176a67f947c3b5e27931bbee2280