Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Hiroyuki Kumeta"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 102996- (2024)
Summary: Mincle (macrophage-inducible C-type lectin, CLEC4E) is a C-type lectin immune-stimulatory receptor that can be targeted for inducing potent adjuvant effects. Mincle can recognize trehalose dimycolate and related glycolipids. Here, we present
Externí odkaz:
https://doaj.org/article/91eb0ce979b24c448a0af611d1b26160
Autor:
Lareno L. Villones, Anna-Kristin Ludwig, Hiroyuki Kumeta, Seiya Kikuchi, Rika Ochi, Tomoyasu Aizawa, Shin-Ichiro Nishimura, Hans-Joachim Gabius, Hiroshi Hinou
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Dystroglycan (DG), which constitutes a part of the dystrophin–glycoprotein complex, connects the extracellular matrix to the cytoskeleton. The matriglycans presented by the extracellular α-DG serve as a contact point with extracellular ma
Externí odkaz:
https://doaj.org/article/3b313ae12f4c4ebbae078d91bb584ce4
Autor:
Koki Suzuki, Ryoya Nojiri, Motonori Matsusaki, Takuya Mabuchi, Shingo Kanemura, Kotone Ishii, Hiroyuki Kumeta, Masaki Okumura, Tomohide Saio, Takahiro Muraoka
Publikováno v:
Chemical Science; 8/28/2024, Vol. 15 Issue 32, p12676-12685, 10p
Autor:
Zihao Song, Yuki Ohnishi, Seiji Osada, Li Gan, Jiaxi Jiang, Zhiyan Hu, Hiroyuki Kumeta, Yasuhiro Kumaki, Yuki Yokoi, Kiminori Nakamura, Tokiyoshi Ayabe, Kazuo Yamauchi, Tomoyasu Aizawa
Publikováno v:
Metabolites, Vol 13, Iss 5, p 611 (2023)
Nuclear magnetic resonance (NMR)-based metabolomics, which comprehensively measures metabolites in biological systems and investigates their response to various perturbations, is widely used in research to identify biomarkers and investigate the path
Externí odkaz:
https://doaj.org/article/bf624b2ec55645f683f74859aa234358
Autor:
Soichiro Kawagoe, Munehiro Kumashiro, Takuya Mabuchi, Hiroyuki Kumeta, Koichiro Ishimori, Tomohide Saio
Publikováno v:
Biochemistry. 61:2897-2908
A transcriptional regulatory system called heat shock response (HSR) has been developed in eukaryotic cells to maintain proteome homeostasis under various stresses. Heat shock factor-1 (Hsf1) plays a central role in HSR, mainly by upregulating molecu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Although fish is an important part of the human diet, it is also a common source of food allergy. The major allergen in fish is parvalbumin, a well-conserved Ca2+-binding protein found in the white muscle of many fish species. Here, we studi
Externí odkaz:
https://doaj.org/article/509fb3e6bfff4ba0852209bf3ff83bf0
Autor:
Akinori Yamasaki, Yasunori Watanabe, Wakana Adachi, Kuninori Suzuki, Kazuaki Matoba, Hiromi Kirisako, Hiroyuki Kumeta, Hitoshi Nakatogawa, Yoshinori Ohsumi, Fuyuhiko Inagaki, Nobuo N. Noda
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 19-27 (2016)
Selective autophagy mediates the degradation of various cargoes, including protein aggregates and organelles, thereby contributing to cellular homeostasis. Cargo receptors ensure selectivity by tethering specific cargo to lipidated Atg8 at the isolat
Externí odkaz:
https://doaj.org/article/2145ef6370a34e13b22cd5456ff4702c
Autor:
Hiroshi Nakagawa, Mizue Asada, Koichiro Ishimori, Kazumi Shimizu, Tomohide Saio, Toshikazu Nakamura, Soya Hiramatsu, Hiroyuki Kumeta
Publikováno v:
Biophysical journal. 120(15):2943-2951
Despite their importance in function, the conformational state of proteins and its changes are often poorly understood, mainly because of the lack of an efficient tool. MurD, a 47-kDa protein enzyme responsible for peptidoglycan biosynthesis, is one
Autor:
Kengo Yanagawa, Ayaka Kajikawa, Sayaka Sakakibara, Hiroyuki Kumeta, Hiroya Tomita, Ken'ichiro Matsumoto
Publikováno v:
Biophysical Chemistry. 296:107001
Autor:
Hao Gu, Takasumi Kato, Hiroyuki Kumeta, Yasuhiro Kumaki, Takashi Tsukamoto, Takashi Kikukawa, Makoto Demura, Hiroaki Ishida, Hans J. Vogel, Tomoyasu Aizawa
Publikováno v:
ACS omega. 7(36)
Cecropin P1 (CP1) isolated from a large round-worm Ascaris suum, which is found in pig intestines, has been extensively studied as a model antimicrobial peptide (AMP). However, despite being a model AMP, its antibacterial mechanism is not well unders