Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Hiroyuki Kishimoto"'
Autor:
Ryo Mashita, Yasumasa Bito, Kentaro Uesugi, Masato Hoshino, Ikuo Kageyuki, Hiroyuki Kishimoto, Wataru Yashiro, Toshiji Kanaya
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Notwithstanding the various uses of rubber, the fracture mechanism of filler-reinforced rubber remains unclear. This study used four-dimensional computed tomography (4D-CT) involving monochromatic synchrotron X-rays to examine the cavitation
Externí odkaz:
https://doaj.org/article/a7e475bc8cad43308f89e7dfdc6eeef3
Autor:
Nanako Hata, Kunitoshi Shigeyasu, Yuzo Umeda, Shuya Yano, Sho Takeda, Kazuhiro Yoshida, Tomokazu Fuji, Ryuichi Yoshida, Kazuya Yasui, Hibiki Umeda, Toshiaki Takahashi, Yoshitaka Kondo, Hiroyuki Kishimoto, Yoshiko Mori, Fuminori Teraishi, Hideki Yamamoto, Hiroyuki Michiue, Keiichiro Nakamura, Hiroshi Tazawa, Toshiyoshi Fujiwara
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Adenosine-to-inosine RNA editing is a process mediated by adenosine deaminases that act on the RNA (ADAR) gene family. It has been discovered recently as an epigenetic modification dysregulated in human cancers. However, the clinical signifi
Externí odkaz:
https://doaj.org/article/1b35ada8af264014af6e837a45dcee55
Publikováno v:
Journal of Synchrotron Radiation, Vol 29, Iss 5, Pp 1180-1186 (2022)
A synchrotron-radiation-based quasi-elastic γ-ray scattering system has been developed that uses time-domain interferometry to observe microscopic polymer dynamics under uniaxial deformation. The stress-producing mechanism of crosslinked polybutadie
Externí odkaz:
https://doaj.org/article/8f6846af1e3b44fb97635c0774cbf827
Autor:
Yasuhiro Komatsu, Kunitoshi Shigeyasu, Shuya Yano, Sho Takeda, Kazutaka Takahashi, Nanako Hata, Hibiki Umeda, Kazuhiro Yoshida, Yoshiko Mori, Kazuya Yasui, Ryuichi Yoshida, Yoshitaka Kondo, Hiroyuki Kishimoto, Fuminori Teraishi, Yuzo Umeda, Shunsuke Kagawa, Hiroyuki Michiue, Hiroshi Tazawa, Ajay Goel, Toshiyoshi Fujiwara
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Most cases of colorectal cancers (CRCs) are microsatellite stable (MSS), which frequently demonstrate lower response rates to immune checkpoint inhibitors (ICIs). RNA editing produces neoantigens by altering amino acid sequences. In this stu
Externí odkaz:
https://doaj.org/article/c90d34251c284bdca99ee1e311b271a2
Autor:
Nozomu Ishiguro, Fusae Kaneko, Masaki Abe, Yuki Takayama, Junya Yoshida, Taiki Hoshino, Shuntaro Takazawa, Hideshi Uematsu, Yuhei Sasaki, Naru Okawa, Keichi Takahashi, Hiroyuki Takizawa, Hiroyuki Kishimoto, Yukio Takahashi
Publikováno v:
Applied Physics Express, Vol 17, Iss 5, p 052006 (2024)
As the first experiment at BL10U in NanoTerasu, tender X-ray ptychographic coherent diffraction imaging (PCDI) was conducted using a photon energy of 3.5 keV. The ptychographic diffraction patterns from a 200 nm thick Ta test chart and a micrometer-s
Externí odkaz:
https://doaj.org/article/23f2876cccc24d48b795e637d8587189
Autor:
Fumitaka Taniguchi, Akihiro Nyuya, Toshiaki Toshima, Kazuya Yasui, Yoshiko Mori, Makoto Okawaki, Hiroyuki Kishimoto, Yuzo Umeda, Toshiyoshi Fujiwara, Hiroaki Tanioka, Yoshiyuki Yamaguchi, Ajay Goel, Takeshi Nagasaka
Publikováno v:
Future Science OA, Vol 7, Iss 10 (2021)
Aim: To evaluate whether PCR-reverse sequence-specific oligonucleotide can examine the concordance between liquid biopsy and metastatic lesions with acquired resistance. Materials & methods: We examined acquired mutations in chemoresistant lesions an
Externí odkaz:
https://doaj.org/article/ea0e4ef415a24da2a5f05b5e43157ddd
Autor:
Shuya Yano, Hiroshi Tazawa, Hiroyuki Kishimoto, Shunsuke Kagawa, Toshiyoshi Fujiwara, Robert M. Hoffman
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 879 (2021)
Oncolytic virotherapy is one of the most promising, emerging cancer therapeutics. We generated three types of telomerase-specific replication-competent oncolytic adenovirus: OBP-301; a green fluorescent protein (GFP)-expressing adenovirus, OBP-401; a
Externí odkaz:
https://doaj.org/article/09e5421a2c524bd5910b9303c3b81f36
Publikováno v:
Quantum Beam Science, Vol 4, Iss 4, p 33 (2020)
Recently, we have developed a novel dynamic nuclear polarization (DNP) apparatus with a magnetic field of 7 T and a sample temperature of 1 K. High proton spin polarizations from −84% to 76%, for TEMPO doped polystyrene samples, have been demonstra
Externí odkaz:
https://doaj.org/article/6e0438df119e4678b1b8f4695ea09de4
Autor:
Shohei Oie, Kazuya Matsuzaki, Wataru Yokoyama, Shinji Tokunaga, Tsuyoshi Waku, Song-Iee Han, Naoya Iwasaki, Aya Mikogai, Kayoko Yasuzawa-Tanaka, Hiroyuki Kishimoto, Hiromi Hiyoshi, Yuka Nakajima, Toshiyuki Araki, Keiji Kimura, Junn Yanagisawa, Akiko Murayama
Publikováno v:
Cell Reports, Vol 7, Iss 3, Pp 807-820 (2014)
Ribosome biosynthesis is a major intracellular energy-consuming process. We previously identified a nucleolar factor, nucleomethylin (NML), which regulates intracellular energy consumption by limiting rRNA transcription. Here, we show that, in livers
Externí odkaz:
https://doaj.org/article/de20f559a30e484c88f75979f11e7779
Autor:
Shuya Yano, Kiyoto Takehara, Shinji Miwa, Hiroyuki Kishimoto, Yukihiko Hiroshima, Takashi Murakami, Yasuo Urata, Shunsuke Kagawa, Michael Bouvet, Toshiyoshi Fujiwara, Robert M Hoffman
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148760 (2016)
Fluorescence-guided surgery (FGS) of cancer is an area of intense development. In the present report, we demonstrate that the telomerase-dependent green fluorescent protein (GFP)-containing adenovirus OBP-401 could label colon-cancer liver metastasis
Externí odkaz:
https://doaj.org/article/45737da969774b028b0fd5fd9cff3d96