Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Hiroyuki Kawahara"'
Autor:
Hajime Sanada, Satoshi Hara, Makoto Horita, Hiroyuki Kawahara, Misaki Yoshida, Yoshinori Takahashi, Shunsuke Tsuge, Takeshi Zoshima, Ryo Nishioka, Kiyoaki Ito, Ichiro Mizushima, Takashi Matsushita, Mitsuhiro Kawano
Publikováno v:
BMC Nephrology, Vol 24, Iss 1, Pp 1-6 (2023)
Abstract Background Scleroderma renal crisis (SRC) is a critical kidney involvement of systemic sclerosis (SSc), often resulting in end-stage renal disease. Although the recurrence of SRC in the allograft has been reported, the development of de novo
Externí odkaz:
https://doaj.org/article/b9e5a80ade584a4f8110ceb5cd6a9e04
Autor:
Toshiki Takahashi, Jun Shirai, Miyo Matsuda, Sae Nakanaga, Shin Matsushita, Kei Wakita, Mizuki Hayashishita, Rigel Suzuki, Aya Noguchi, Naoto Yokota, Hiroyuki Kawahara
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106652- (2023)
Summary: The small GTPase Rab8 plays a vital role in the vesicular trafficking of cargo proteins from the trans-Golgi network to target membranes. Upon reaching its target destination, Rab8 is released from the vesicular membrane into the cytoplasm v
Externí odkaz:
https://doaj.org/article/d7e79ac28eb3487e90afa54333338c5c
Autor:
Ryo Nishioka, Satoshi Hara, Hiroyuki Kawahara, Kiyoaki Ito, Ichiro Mizushima, Masayoshi Hirata, Michio Nagata, Mitsuhiro Kawano
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-7 (2021)
Abstract Background Primary Sjögren’s syndrome (pSS) is an auto-immune disease characterized by sialadenitis and dacryoadenitis with lymphoplasmacytic cell infiltration. In pSS, not only sicca symptoms, but also extra-glandular involvement induced
Externí odkaz:
https://doaj.org/article/82d15f3ebae7467c9efd4271eaa763e0
Publikováno v:
FEBS Open Bio, Vol 9, Iss 7, Pp 1281-1291 (2019)
Accumulation of damaged mitochondria is implicated in a number of neurodegenerative disorders, including Parkinson's disease. Therefore, the machinery for mitochondrial quality control is important for the prevention of such diseases. It has been rep
Externí odkaz:
https://doaj.org/article/1ffbb77cfc894519a630c10541e634dc
Publikováno v:
Biology Open, Vol 9, Iss 1 (2020)
Defective translocation of glucose transporter 4 (GLUT4) to the cell surface is a key feature of insulin resistance in type 2 diabetes. Therefore, elucidating the mechanism of GLUT4 translocation is of primary importance. The mammalian Bag6/Bat3 gene
Externí odkaz:
https://doaj.org/article/8ac8c051d69c4f5d973e1b6cc6d5714f
Autor:
Daiki Hira, Asami Suzuki, Yusuke Kono, Kosuke Shimokawa, Serika Matsuoka, Ken-yuh Hasumoto, Hiroyuki Kawahara, Masahide Onoue, Takuya Fujita, Tomonobu Okano, Mikio Kakumoto
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 4, Iss 1, Pp 1-6 (2018)
Abstract Background Colloidal saccharated iron oxide injection is used for the treatment of iron deficiency anemia in patients with a poor oral intake. Because of the poor stability of the colloid particle, there have been concerns regarding its comp
Externí odkaz:
https://doaj.org/article/9fd35ccf632f48b9b779e6084c222e26
Publikováno v:
Biology Open, Vol 7, Iss 3 (2018)
ZFP36L2 promotes the destruction of AU-rich element-containing transcripts, while its regulation and functional significance in cell cycle control are scarcely identified. We show that ZFP36L2 is a cell cycle-regulated CCCH protein, the abundance of
Externí odkaz:
https://doaj.org/article/74238ab4320943cbbfe13315a55cf415
Autor:
Hiroki Kagawa, Yuka Shino, Daigo Kobayashi, Syunsuke Demizu, Masumi Shimada, Hiroyoshi Ariga, Hiroyuki Kawahara
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18638 (2011)
Patched 1 (Ptc1) is a polytopic receptor protein that is essential for growth and differentiation. Its extracellular domains accept its ligand, Sonic Hedgehog, while the function of its C-terminal intracellular domain is largely obscure.In this study
Externí odkaz:
https://doaj.org/article/ece31e0a8a474ff6942005308a2d7742
Autor:
Hiroyuki Kawahara, Ichiro Mizushima, Shunsuke Tsuge, Seung Shin, Takahiro Yoshinobu, Ryohei Hoshiba,, Ryo Nishioka, Takeshi Zoshima, Satoshi Hara, Kiyoaki Ito, Mitsuhiro Kawano
Publikováno v:
Modern Rheumatology; Nov2023, Vol. 33 Issue 6, p1154-1161, 8p
Publikováno v:
Biochemical Journal; Oct2023, Vol. 480 Issue 19, p1583-1598, 16p