Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hiroyuki IKUTA"'
Autor:
Hiroyuki Ikuta, Hiroaki Shimada, Kenjiro Sakamoto, Rena Nakamura, Atsushi Kawase, Masahiro Iwaki
Publikováno v:
Xenobiotica. 52:653-660
Acyl glucuronides (AGs) are known as one of the causes of idiosyncratic drug toxicity (IDT). Although AGs can be enzymatically hydrolysed by β-glucuronidase and esterase, much information on their characteristics and species differences is lacking.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d340962d3c9f74d0f5f2cce160b9fc5
https://doi.org/10.1080/00498254.2022.2131484
https://doi.org/10.1080/00498254.2022.2131484
Autor:
Kotone MATSUYAMA, Yutaka SATO, Hiroaki SHIMASE, null Keiko MITA, Nobuyuki HANAMURA, Masanobu MINAMINO, Toshiyuki OKADA, Hiroyuki IKUTA, Keiichi INAIZUMI
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 53:67-73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d06b043e3c409fbe4db721d466eaed86
https://doi.org/10.3999/jscpt.53.3_67
https://doi.org/10.3999/jscpt.53.3_67
Autor:
Hiroaki, Shimada, Hiroyuki, Ikuta, Keisuke, Kumazawa, Manato, Nomi, Mayumi, Shiojiri, Atsushi, Kawase, Masahiro, Iwaki
Publikováno v:
European Journal of Pharmaceutical Sciences. 174:106193
Acyl glucuronides (AGs) are considered to cause idiosyncratic drug toxicity (IDT), and evaluating the chemical instability of AGs may be useful for predicting the IDT risk of novel drug candidates. However, AGs show variations in their chemical insta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adc69bf2d1a953ea2ef0a0584ed784ff
https://doi.org/10.1016/j.ejps.2022.106193
https://doi.org/10.1016/j.ejps.2022.106193
Autor:
Michihiro Natori, Hiroshi Yamakawa, Akihito Watanabe, Nobukatsu Okuizumi, Hiroyuki Ikuta, Shinya Hakata
Publikováno v:
3rd AIAA Spacecraft Structures Conference.
Stepwise deployments of a membrane structure with rolled-up booms have been investigated. The boom consists of two bi-convex tapes covered by a braid sleeve. The boom can be smoothly rolled up and unrolled by elastic deformation. In this paper, new l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::677dfea1458238550c04ead60a2d8554
https://doi.org/10.2514/6.2016-1471
https://doi.org/10.2514/6.2016-1471
Publikováno v:
Xenobiotica. 38:1410-1421
1. The effects of adjuvant-induced arthritis on the chiral inversion of 'profens', a type of non-steroidal anti-inflammatory drug, have hardly been investigated. The authors investigated the effects of adjuvant-induced arthritis on the chiral inversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de8d481c1320f77b3b8f49ac2368aad
https://doi.org/10.1080/00498250802483768
https://doi.org/10.1080/00498250802483768
Publikováno v:
TRANSACTIONS OF THE JAPAN FLUID POWER SYSTEM SOCIETY. 34:119-125
Quick response solenoid valves acting as simple on-off hydraulic control devices are inexpensive and easy to operate. There are several hydraulic cylinder control methods using the quick response solenoid valves, which control the flow rate by varyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::965f5419ce0fed4e78a1a757b3e3a424
https://doi.org/10.5739/jfps.34.119
https://doi.org/10.5739/jfps.34.119
Autor:
Nobukatsu Okuizumi, Hiroyuki Ikuta, Hiroshi Yamakawa, Masakazu Yamazaki, Michihiro Natori, Nobuhisa Katsumata, Yuki Ito, Hiroaki Kobayashi
Publikováno v:
Spacecraft Structures Conference.
In this paper, simple deployable structures are introduced, which consist of polygonal membranes and elastic booms deployed by only releasing the rolled-up booms in stepwise manners. The membranes are folded up with modified spiral folding patterns t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e08baf7fac9f9a7a563e3c37cfb06f3
https://doi.org/10.2514/6.2014-1039
https://doi.org/10.2514/6.2014-1039
Autor:
Hiroyuki Ikuta, Atsushi Kawase, Tomoaki Nagao, Naomi Akitsu, Kana Yamamoto, Satoshi Uno, Masahiro Iwaki
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 43(3)
Adjuvant-induced arthritis (AA) in the rat is used as a model for rheumatoid arthritis. In AA rats, the pharmacokinetics of various drugs is affected due to the alterations of plasma protein binding of drugs. We choose propranolol (PL) and flurbiprof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afcf6484299992fb382649e064d22a82
https://pubmed.ncbi.nlm.nih.gov/22867272
https://pubmed.ncbi.nlm.nih.gov/22867272
Publikováno v:
Volume 8: Seismic Engineering.
This paper deals with nonlinear vibration of a continuum system with gaps under random waves considered collision phenomena. In order to investigate this nonlinear vibration characteristic, experiments are made with an experimental apparatus consisti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71e9d01a2445106638b944408d555ea9
https://doi.org/10.1115/pvp2005-71429
https://doi.org/10.1115/pvp2005-71429
Publikováno v:
Volume 8: Seismic Engineering.
This paper deals with nonlinear vibration characteristics of a continuum system with collision phenomena under random waves with gaps. In order to investigate such a nonlinear vibration characteristic, an experimental apparatus consisting of a nonlin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caf454a97136b4ba9a69f97547a19ee7
https://doi.org/10.1115/pvp2005-71428
https://doi.org/10.1115/pvp2005-71428