Výsledky vyhledávání - "Hiroyuki FUJIKI"

Akademický článek

In vitro and in vivo pharmacological profile of OPC-61815, a water-soluble phosphate ester pro-drug of tolvaptan

Autor: Hiroyuki Fujiki, Masayuki Matsunaga, Masayuki Furukawa, Tatsuya Yamashita, Shigeki Nakamura, Toshiki Miyazaki, Hiroshi Mizuguchi, Yasuhiro Menjo, Takakuni Matsuda, Yoshihisa Yamada

Publikováno v: Journal of Pharmacological Sciences, Vol 150, Iss 3, Pp 163-172 (2022)

Tolvaptan is an orally active vasopressin V2 receptor antagonist and used for the treatment of volume overload in some disease as an aquaretic. Tolvaptan sodium phosphate (OPC-61815) is a pro-drug of tolvaptan that was designed to improve water solub

Externí odkaz: https://doaj.org/article/c82130652ee54de69dd482bcfc9245ac

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Akademický článek

Reverse heat flow with Peltier-induced thermoinductive effect

Autor: Kenjiro Okawa, Yasutaka Amagai, Hiroyuki Fujiki, Nobu-Hisa Kaneko

Publikováno v: Communications Physics, Vol 4, Iss 1, Pp 1-8 (2021)

Most electrical components have an equivalent thermal-based counterpart however some devices, such as an inductor, can be more difficult to realise than others. Here, the authors demonstrate a Peltier-induced thermoinductive effect theoretically and

Externí odkaz: https://doaj.org/article/733e86e86f4a40859bef58761e4b4da0

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Akademický článek

Tolvaptan Attenuates Left Ventricular Fibrosis After Acute Myocardial Infarction in Rats

Autor: Takanori Yamazaki, Yasuhiro Nakamura, Masayuki Shiota, Mayuko Osada-Oka, Hiroyuki Fujiki, Akihisa Hanatani, Kenei Shimada, Katsuyuki Miura, Minoru Yoshiyama, Hiroshi Iwao, Yasukatsu Izumi

Publikováno v: Journal of Pharmacological Sciences, Vol 123, Iss 1, Pp 58-66 (2013)

Tolvaptan, a non-peptide V2-receptor antagonist, is a newly developed diuretic agent. Recently, we reported that tolvaptan has diuretic as well as anti-inflammatory and anti-fibrotic actions in chronic heart failure. In this study, we investigated wh

Externí odkaz: https://doaj.org/article/07dd875e90c2448fb96a0e0634fb5c2e

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Relationship between internal pressure strength of flexible metal tubes and bellows shapes

Autor: Katsuya Fujimoto, Hiroyuki Fujiki, Masashi Daimaruya, Hiroyuki Yamada

Publikováno v: Strength, Fracture and Complexity. :1-19

BACKGROUND: This study is concerned with the development of the hydrogen gas dispenser used in hydrogen stations for fuel cell vehicles (FCV). Most of the current flexible hoses suppling the high-pressure hydrogen gas to FCV are made of rubber and re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a7466b3d1cd7cf7bdf9bf1c7cab2627
https://doi.org/10.3233/sfc-232000

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