Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hiroyuki, Suetsugu"'
Autor:
Shuji Ito, Hiroshi Takuwa, Saori Kakehi, Yuki Someya, Hideyoshi Kaga, Nobuyuki Kumahashi, Suguru Kuwata, Takuya Wakatsuki, Masaru Kadowaki, Soichiro Yamamoto, Takafumi Abe, Miwako Takeda, Yuki Ishikawa, Xiaoxi Liu, Nao Otomo, Hiroyuki Suetsugu, Yoshinao Koike, Keiko Hikino, Kohei Tomizuka, Yukihide Momozawa, Kouichi Ozaki, Minoru Isomura, Toru Nabika, Haruka Kaneko, Muneaki Ishijima, Ryuzo Kawamori, Hirotaka Watada, Yoshifumi Tamura, Yuji Uchio, Shiro Ikegawa, Chikashi Terao
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract Sarcopenia is a common skeletal muscle disease in older people. Lower limb muscle strength is a good predictive value for sarcopenia; however, little is known about its genetic components. Here, we conducted a genome-wide association study (
Externí odkaz:
https://doaj.org/article/cd023cc995e649fbbe15c12e3ca897d0
Autor:
Yuki Ishikawa, Nao Tanaka, Yoshihide Asano, Masanari Kodera, Yuichiro Shirai, Mitsuteru Akahoshi, Minoru Hasegawa, Takashi Matsushita, Kazuyoshi Saito, Sei-ichiro Motegi, Hajime Yoshifuji, Ayumi Yoshizaki, Tomohiro Kohmoto, Kae Takagi, Akira Oka, Miho Kanda, Yoshihito Tanaka, Yumi Ito, Kazuhisa Nakano, Hiroshi Kasamatsu, Akira Utsunomiya, Akiko Sekiguchi, Hiroaki Niiro, Masatoshi Jinnin, Katsunari Makino, Takamitsu Makino, Hironobu Ihn, Motohisa Yamamoto, Chisako Suzuki, Hiroki Takahashi, Emi Nishida, Akimichi Morita, Toshiyuki Yamamoto, Manabu Fujimoto, Yuya Kondo, Daisuke Goto, Takayuki Sumida, Naho Ayuzawa, Hidetoshi Yanagida, Tetsuya Horita, Tatsuya Atsumi, Hirahito Endo, Yoshihito Shima, Atsushi Kumanogoh, Jun Hirata, Nao Otomo, Hiroyuki Suetsugu, Yoshinao Koike, Kohei Tomizuka, Soichiro Yoshino, Xiaoxi Liu, Shuji Ito, Keiko Hikino, Akari Suzuki, Yukihide Momozawa, Shiro Ikegawa, Yoshiya Tanaka, Osamu Ishikawa, Kazuhiko Takehara, Takeshi Torii, Shinichi Sato, Yukinori Okada, Tsuneyo Mimori, Fumihiko Matsuda, Koichi Matsuda, Tiffany Amariuta, Issei Imoto, Keitaro Matsuo, Masataka Kuwana, Yasushi Kawaguchi, Koichiro Ohmura, Chikashi Terao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Here we report the largest Asian genome-wide association study (GWAS) for systemic sclerosis performed to date, based on data from Japanese subjects and comprising of 1428 cases and 112,599 controls. The lead SNP is in the FCGR/FCRL region,
Externí odkaz:
https://doaj.org/article/2821292baef747248e9e487cef06ad07
Autor:
Shuji Ito, Xiaoxi Liu, Yuki Ishikawa, David D. Conti, Nao Otomo, Zsofia Kote-Jarai, Hiroyuki Suetsugu, Rosalind A. Eeles, Yoshinao Koike, Keiko Hikino, Soichiro Yoshino, Kohei Tomizuka, Momoko Horikoshi, Kaoru Ito, Yuji Uchio, Yukihide Momozawa, Michiaki Kubo, The BioBank Japan Project, Yoichiro Kamatani, Koichi Matsuda, Christopher A. Haiman, Shiro Ikegawa, Hidewaki Nakagawa, Chikashi Terao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Prostate cancer (PrCa) is the second most common cancer worldwide in males. While strongly warranted, the prediction of mortality risk due to PrCa, especially before its development, is challenging. Here, we address this issue by maximizing
Externí odkaz:
https://doaj.org/article/ee30aa5cf88e456e9ab064b3dd8991f6
Autor:
Yoshinao Koike, Masahiko Takahata, Masahiro Nakajima, Nao Otomo, Hiroyuki Suetsugu, Xiaoxi Liu, Tsutomu Endo, Shiro Imagama, Kazuyoshi Kobayashi, Takashi Kaito, Satoshi Kato, Yoshiharu Kawaguchi, Masahiro Kanayama, Hiroaki Sakai, Takashi Tsuji, Takeshi Miyamoto, Hiroyuki Inose, Toshitaka Yoshii, Masafumi Kashii, Hiroaki Nakashima, Kei Ando, Yuki Taniguchi, Kazuhiro Takeuchi, Shuji Ito, Kohei Tomizuka, Keiko Hikino, Yusuke Iwasaki, Yoichiro Kamatani, Shingo Maeda, Hideaki Nakajima, Kanji Mori, Atsushi Seichi, Shunsuke Fujibayashi, Tsukasa Kanchiku, Kei Watanabe, Toshihiro Tanaka, Kazunobu Kida, Sho Kobayashi, Masahito Takahashi, Kei Yamada, Hiroshi Takuwa, Hsing-Fang Lu, Shumpei Niida, Kouichi Ozaki, Yukihide Momozawa, Genetic Study Group of Investigation Committee on Ossification of the Spinal Ligaments, Masashi Yamazaki, Atsushi Okawa, Morio Matsumoto, Norimasa Iwasaki, Chikashi Terao, Shiro Ikegawa
Publikováno v:
eLife, Vol 12 (2023)
Ossification of the posterior longitudinal ligament of the spine (OPLL) is an intractable disease leading to severe neurological deficits. Its etiology and pathogenesis are primarily unknown. The relationship between OPLL and comorbidities, especiall
Externí odkaz:
https://doaj.org/article/eda7d0627866429283f54547e72b72f0
Autor:
Yuki Ishikawa, Nao Tanaka, Yoshihide Asano, Masanari Kodera, Yuichiro Shirai, Mitsuteru Akahoshi, Minoru Hasegawa, Takashi Matsushita, Kazuyoshi Saito, Sei-ishiro Motegi, Hajime Yoshifuji, Ayumi Yoshizaki, Tomohiro Komoto, Kae Takagi, Akira Oka, Miho Kanda, Yoshihito Tanak, Yumi Ito, Kazuhisa Nakano, Hiroshi Kasamatsu, Akira Utsunomiya, Akiko Sekiguchi, Hiroaki Niro, Masatoshi Jinnin, Katsunari Makino, Takamitsu Makino, Hironobu Ihn, Motohisa Yamamoto, Chisako Suzuki, Hiroki Takahashi, Emi Nishida, Akimichi Morita, Toshiyuki Yamamoto, Manabu Fujimoto, Yuya Kondo, Daisuke Goto, Takayuki Sumida, Naho Ayuzawa, Hidetashi Yanagida, Tetsuya Horita, Tatsuya Atsumi, Hirahito Endo, Yoshihito Shima, Atsushi Kumanogoh, Jun Hirata, Nao Otomo, Hiroyuki Suetsugu, Yoshinao Koike, Kohei Tomizuka, Soichiro Yoshino, Xiaoxi Liu, Shuji Ito, Keiko Hikino, Akari Suzuki, Yukihide Momozawa, Shiro Ikegawa, Yoshiya Tanaka, Osamu Ishikawa, Kazuhiko Takehara, Takeshi Torii, Shinichi Sato, Yukinori Okada, Tsuneyo Mimori, Fumihiko Matsuda, Koichi Matsuda, Tiffany Amariuta, Issei Imoto, Keitaro Matsuo, Masataka Kuwana, Yasushi Kawaguchi, Koichiro Ohmura, Chikashi Terao
We conducted a Japanese GWAS for systemic sclerosis (SSc) comprising 1,428 cases and 112,599 controls, the largest Asian GWAS for SSc ever, and identified three novel signals. The lead SNP in FCGR/FCRL region had a strong effect size (OR 2.05, P = 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c211a504e6abe4bb4b7e51e21895eaa5
https://doi.org/10.21203/rs.3.rs-2712663/v1
https://doi.org/10.21203/rs.3.rs-2712663/v1
Autor:
Xianyong, Yin, Kwangwoo, Kim, Hiroyuki, Suetsugu, So-Young, Bang, Leilei, Wen, Masaru, Koido, Eunji, Ha, Lu, Liu, Yuma, Sakamoto, Sungsin, Jo, Rui-Xue, Leng, Nao, Otomo, Young-Chang, Kwon, Yujun, Sheng, Nobuhiko, Sugano, Mi Yeong, Hwang, Weiran, Li, Masaya, Mukai, Kyungheon, Yoon, Minglong, Cai, Kazuyoshi, Ishigaki, Won Tae, Chung, He, Huang, Daisuke, Takahashi, Shin-Seok, Lee, Mengwei, Wang, Kohei, Karino, Seung-Cheol, Shim, Xiaodong, Zheng, Tomoya, Miyamura, Young Mo, Kang, Dongqing, Ye, Junichi, Nakamura, Chang-Hee, Suh, Yuanjia, Tang, Goro, Motomura, Yong-Beom, Park, Huihua, Ding, Takeshi, Kuroda, Jung-Yoon, Choe, Chengxu, Li, Hiroaki, Niiro, Youngho, Park, Changbing, Shen, Takeshi, Miyamoto, Ga-Young, Ahn, Wenmin, Fei, Tsutomu, Takeuchi, Jung-Min, Shin, Keke, Li, Yasushi, Kawaguchi, Yeon-Kyung, Lee, Yong-Fei, Wang, Koichi, Amano, Dae Jin, Park, Wanling, Yang, Yoshifumi, Tada, Yu Lung, Lau, Ken, Yamaji, Zhengwei, Zhu, Masato, Shimizu, Takashi, Atsumi, Akari, Suzuki, Takayuki, Sumida, Yukinori, Okada, Koichi, Matsuda, Keitaro, Matsuo, Yuta, Kochi, Kazuhiko, Yamamoto, Koichiro, Ohmura, Tae-Hwan, Kim, Sen, Yang, Takuaki, Yamamoto, Bong-Jo, Kim, Nan, Shen, Shiro, Ikegawa, Hye-Soon, Lee, Xuejun, Zhang, Chikashi, Terao, Yong, Cui, Sang-Cheol, Bae
Publikováno v:
Annals of the Rheumatic Diseases. 81:1273-1280
ObjectiveGenome-wide association studies (GWAS) have identified >100 risk loci for systemic lupus erythematosus (SLE), but the disease genes at most loci remain unclear, hampering translation of these genetic discoveries. We aimed to prioritise genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc23aefa6fc3463b28c74e1115214ed
https://doi.org/10.1136/annrheumdis-2022-222345
https://doi.org/10.1136/annrheumdis-2022-222345
Autor:
Hiroyuki Suetsugu, Yukihide Momozawa, Masaru Koido, Akari Suzuki, Nao Otomo, Nao Tanaka, Yuta Kochi, Kouhei Tomizuka, Chikashi Terao, Yoichiro Kamatani, Shiro Ikegawa, Kazuhiko Yamamoto
Publikováno v:
Journal of Allergy and Clinical Immunology. 148:1293-1306
Background Atopic dermatitis (AD) is the most common allergic disease in the world. While genetic components play critical roles in its pathophysiology, a large proportion of its genetic background is still unexplored. Objectives This study sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e425ef34009d7016cd9fc8df339ca9
https://doi.org/10.1016/j.jaci.2021.04.019
https://doi.org/10.1016/j.jaci.2021.04.019
Publikováno v:
Asian Spine Journal, Vol 9, Iss 3, Pp 461-464 (2015)
The breakage of an epidural catheter is an extremely rare complication. We describe a unique case where a retained epidural catheter fragment after epidural anesthesia was treated by surgery. The epidural catheter broke during its removal, requiring
Externí odkaz:
https://doaj.org/article/b3ac5dea577e495b843f188aa5f3dd4f
Autor:
Yeon-Kyung Lee, Kohei Karino, Dae Jin Park, Xiaoting Chen, Xiaodong Zheng, Dong-Qing Ye, So-Young Bang, Leilei Wen, Tae-Hwan Kim, Takuaki Yamamoto, Yukinori Okada, Young Mo Kang, Sreeja Parameswaran, Xuejun Zhang, Cheng-Xu Li, Eunji Ha, Sang Cheol Bae, Hiroyuki Suetsugu, Koichi Amano, Tsutomu Takeuchi, Takayuki Sumida, Ken Yamaji, Hye-Soon Lee, Yuanjia Tang, Seung-Cheol Shim, Viktoryia Laurynenka, Sen Yang, Wanling Yang, Yujun Sheng, Xianyong Yin, Koichi Matsuda, Keitaro Matsuo, Akari Suzuki, Chang-Hee Suh, Weiran Li, Kwangwoo Kim, Lu Liu, Kyungheon Yoon, Bong-Jo Kim, Mi Yeong Hwang, Takeshi Kuroda, Shruti Eswar, Koichiro Ohmura, Keke Li, Tomoya Miyamura, Shiro Ikegawa, Hanan Salim, Yuta Kochi, Chikashi Terao, Won Tae Chung, Sungsin Jo, Changbing Shen, Kazuhiko Yamamoto, Daisuke Takahashi, Mengwei Wang, Masaya Mukai, Minglong Cai, Matthew T. Weirauch, Nao Otomo, Kazuyoshi Ishigaki, Yuma Sakamoto, Nan Shen, Hiroaki Niiro, Takashi Atsumi, Yong-Fei Wang, Junichi Nakamura, Young-Chang Kwon, Leah C. Kottyan, Yong Cui, John B. Harley, Goro Motomura, Masato Shimizu, Yasushi Kawaguchi, Nobuhiko Sugano, Rui-Xue Leng, Jung-Yoon Choe, Takeshi Miyamoto, Yong Beom Park, Jung-Min Shin, Masaru Koido, G.Y. Ahn, Huihua Ding, Wen-Min Fei, Shin-Seok Lee, Young-Ho Park, He Huang, Yoshifumi Tada
Publikováno v:
Annals of the Rheumatic Diseases
ObjectiveSystemic lupus erythematosus (SLE), an autoimmune disorder, has been associated with nearly 100 susceptibility loci. Nevertheless, these loci only partially explain SLE heritability and their putative causal variants are rarely prioritised,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1df8536416d1f595b9d0eb715661c09
https://doi.org/10.1136/annrheumdis-2020-219209
https://doi.org/10.1136/annrheumdis-2020-219209
Autor:
Masahiro Nakano, Mineto Ota, Yusuke Takeshima, Yukiko Iwasaki, Hiroaki Hatano, Yasuo Nagafuchi, Takahiro Itamiya, Junko Maeda, Ryochi Yoshida, Saeko Yamada, Aya Nishiwaki, Haruka Takahashi, Hideyuki Takahashi, Yuko Akutsu, Takeshi Kusuda, Hiroyuki Suetsugu, Lu Liu, Kwangwoo Kim, Xianyong Yin, So-Young Bang, Yong Cui, Hye-Soon Lee, Hirofumi Shoda, Xuejun Zhang, Sang-Cheol Bae, Chikashi Terao, Kazuhiko Yamamoto, Tomohisa Okamura, Kazuyoshi Ishigaki, Keishi Fujio
Systemic lupus erythematosus (SLE) is a complex and heterogeneous autoimmune disease involving multiple immune cells. A major hurdle to the elucidation of SLE pathogenesis is our limited understanding of dysregulated gene expression linked to various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2d9e6b22bb04952b367cfd89b3211b0
https://doi.org/10.1101/2022.01.12.22269137
https://doi.org/10.1101/2022.01.12.22269137