Zobrazeno 1 - 10 of 38 pro vyhledávání: '"Hiroyoshi Sawada"'
1
Ceramide-induced Translocation of Protein Kinase C-δ and -ϵ to the Cytosol
Autor: Hisanori Umehara, Shuji Kishi, Toshiro Okazaki, Masaro Tashima, Yasushi Takeda, Naochika Domae, Hirofumi Sawai, Hiroyoshi Sawada, Minoru Okuma
Publikováno v: Journal of Biological Chemistry. 272:2452-2458
Ceramide is now recognized as an intracellular lipid signal mediator, which induces various kinds of cell functions including apoptosis. Ceramide-induced apoptosis was reported to be blocked by 12-O-tetradecanoylphorbol 13-acetate, a protein kinase C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::360c0d39ee8dd9c317a2239c268478b8
https://doi.org/10.1074/jbc.272.4.2452
Zobrazit plný text záznamu
2
Low Levels of Free Endotoxin Result from Carbapenem Treatment of Gram-Negative Bacteria
Autor: Hiroyoshi Sawada, Masaro Tashima, Tomoko Toi-Matsuda, Yasushi Takeda, Hirobumi Sawai, Minoru Okuma
Publikováno v: Journal of Infection and Chemotherapy. 3:27-32
We investigated the effects of imipenam (IPM), 3 new carbapenems (PAPM, BIPM, MEPM) and 2 cephems (CZX, CAZ) on the release of free endotoxin from 2 clinically isolated gram-negative bacteria (Escherichia coli andPseudomonas aeruginosa). On the growt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d24ce3fd2bdb5bb570b66005923a3aef
https://doi.org/10.1007/bf02489181
Zobrazit plný text záznamu
3
Requirement of AP-1 for Ceramide-induced Apoptosis in Human Leukemia HL-60 Cells
Autor: Minoru Okuma, Yasushi Takeda, Hirofumi Sawai, Hiroyoshi Sawada, Masaro Tashima, Hirotaka Yamamoto, Naochika Domae, Hisanori Umehara, Toshiro Okazaki, Hiroto Ishikura, Hakuro Okano
Publikováno v: Journal of Biological Chemistry. 270:27326-27331
Ceramide has emerged as a novel lipid mediator in cell proliferation, differentiation, and apoptosis. In this work, we demonstrate that the levels of c-jun mRNA, c-Jun protein, and DNA binding activity of a nuclear transcription factor AP-1 to 12-o-t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63897f8fb3ba1146900d8fb3a4ef762
https://doi.org/10.1074/jbc.270.45.27326
Zobrazit plný text záznamu
4
Erythroid differentiation and growth inhibition of K562 cells by 2′,5′-dideoxyadenosine: Synergism with interferon-α
Autor: Minoru Okuma, Yasushi Takeda, Tomoko Toi, Kazuei Ogawa, Masaro Tashima, Hirofumi Sawai, Hiroyoshi Sawada, Yukio Maruyama
Publikováno v: Leukemia Research. 19:749-755
We found that 2',5'-dideoxyadenosine (DDA), a P-site specific adenylate cyclase inhibitor, inhibited the growth of K562 cells and caused them to become benzidine positive. The continuous exposure of cells to DDA was needed to recruit cells for growth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4154c629e2beb443d9da215fe1ebce0e
https://doi.org/10.1016/0145-2126(95)00053-q
Zobrazit plný text záznamu
5
High expression of c-kit in K562YO cells due to the prolonged half-life of its mRNA: the effects of modification with serine/threonine kinase signals
Autor: Tomoko Toi, Yasushi Takeda, Kazuei Ogawa, Toshiro Okazaki, Masaro Tashima, Hirofumi Sawai, Hiroyoshi Sawada, Minoru Okuma, Yukio Maruyama
Publikováno v: Blood. 85:1496-1503
We previously reported that the K562 cell line K562YO expressed a high level of the c-kit gene. In this study, we analyzed the mechanism of this expression and investigated the effects of the serine/threonine kinases such as protein kinase C (PKC) an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458a02e66fcd65312761cea6421a54bf
https://doi.org/10.1182/blood.v85.6.1496.bloodjournal8561496
Zobrazit plný text záznamu
6
Molecular Basis of β-Thalassemia in Japan: Heterogeneity and Origins of Mutations
Autor: Jun Ichi Manabe, Naokuni Uike, Shouichi Ohga, Mitsuo Kozuru, Yuji Moriwaki, Michihisa Nomiyama, Hideyuki Nukina, Junji Nishimura, Mari Mineta, Satoshi Shirahata, Nagatomo Ohi, Motoshi Ichinose, Chieko Wakamatsu, Takumi Harada, Hiroyoshi Sawada, Yasuyuki Fukumaki, Supan Fucharoen
Publikováno v: Acta Haematologica. 91:136-143
Characterization of beta-thalassemia mutations was attempted for 13 unrelated Japanese patients heterozygous for beta-thalassemia. We have systematically analyzed beta-thalassemia genes using polymerase-chain-reaction-related techniques; dot blot hyb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ba8ff241bfc7faebf14ad421b5bd67
https://doi.org/10.1159/000204319
Zobrazit plný text záznamu
7
Locomotion transition scheme with instability evaluation using Bayesian Network
Autor: Yasuhisa Hasegawa, Toshio Fukuda, Tadayoshi Aoyama, Hiroyoshi Sawada, Kosuke Sekiyama
Publikováno v: IROS
The applicative field of activities of robots which have only one locomotion strategy is limited. As a mean of enhancing the mobile range, it is necessary to have various locomotion modes. Therefore, we focus on dynamic transitions between several ki
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f176e68a3837e830961255f9db0153ce
https://doi.org/10.1109/iros.2010.5650086
Zobrazit plný text záznamu
8
Dephosphorylation of specific proteins in HL-60 cells by 1α, 25-dihydroxyvitamin D3: Possible involvement of cAMP-dependent protein kinase
Autor: Kato Y, Takeo Ueda, Tetsuya Okuda, Hiroyoshi Sawada, Kazuei Ogawa, Minoru Okuma, Masaro Tashima, Yoshikazu Yumoto, Yataro Yoshida
Publikováno v: Leukemia Research. 15:927-934
Changes of phosphoprotein patterns in HL-60 cells were studied during short exposures to 1α, 25-dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ]. One hundred nanometers 1,25(OH) 2 D 3 dephosphorylated at least three proteins in 6 h: phosphoproteins with molec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c5cb5afbfd879ef392dcc2b7c7504c
https://doi.org/10.1016/0145-2126(91)90169-t
Zobrazit plný text záznamu
10
Use of Ofloxacin in Prevention and Treatment of Secondary Infections in Hematological Malignancies
Autor: Hiroyoshi Sawada, Minoru Okuma, Masaro Tashima
Publikováno v: Chemotherapy. 37:25-32
We evaluated the effectiveness of ofloxacin (OFX) administered for prophylactic purposes during 77 episodes of neutropenia (less than 500/mm3) in 54 patients with hematological malignancies and to combat infection in 17 patients with both hematologic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574c6e8e8143d4b65983901e46deb438
https://doi.org/10.1159/000238903
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje