Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Hiroyoshi Miyakawa"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122263 (2015)
Neurons might interact via electric fields and this notion has been referred to as ephaptic interaction. It has been shown that various types of ion channels are distributed along the dendrites and are capable of supporting generation of dendritic sp
Externí odkaz:
https://doaj.org/article/3bf5d95c8a174c9cbba9535f5febe3c2
Effects of Bifemelane on the Calcium Level and ATP Release of the Human Origin Astrocyte Clonal Cell
Autor:
Yoshitoku Yoshida, Haruno Kumagai, Yoshiumi Ohkubo, Remi Tsuchiya, Mitsuhiro Morita, Hiroyoshi Miyakawa, Yoshihisa Kudo
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 1, Pp 121-128 (2006)
The effect of bifemelane hydrochloride (bifemelane) was examined on human origin astrocyte clonal cells (Kings-1). Bifemelane (125 – 1000 µM) induced a dose-dependent increase in the intracellular calcium concentration ([Ca2+]i). In the highest co
Externí odkaz:
https://doaj.org/article/9d18c84398854cacaeac42d77ca144f2
Autor:
Yoshitoku Yoshida, Remi Tsuchiya, Nagisa Matsumoto, Mitsuhiro Morita, Hiroyoshi Miyakawa, Yoshihisa Kudo
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 2, Pp 212-218 (2005)
We have investigated whether the intracellular calcium concentration ([Ca2+]i) oscillations induced in astrocytes using the metabotropic glutamate-receptor agonist, (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) are Ca2+-dependent, using
Externí odkaz:
https://doaj.org/article/64ff933dcfc94375b214b00106d340a5
Publikováno v:
Journal of Pharmacological Sciences, Vol 95, Iss 3, Pp 341-348 (2004)
Although mannitol has been used as an osmotherapeutic drug on brain injury, the clinical efficiency of the drug are still controversial. In the present study, we examined the effects of mannitol on the edema in a hippocampal slice due to brief ischem
Externí odkaz:
https://doaj.org/article/049fc1e56d3445c0a752d2e5dc916ba3
Autor:
Yoshitoku Yoshida, Nagisa Matsumoto, Remi Tsuchiya, Mitsuhiro Morita, Hiroyoshi Miyakawa, Yoshihisa Kudo
Publikováno v:
Journal of Pharmacological Sciences, Vol 92, Iss 3, Pp 245-251 (2003)
The distribution of group I metabotropic glutamate receptors in rat hippocampal cells in culture was examined by calcium imaging and immunocytochemistry. To distinguish different cell types in the culture, the effects of t-ACPD ((1S,3R)-1-aminocyclop
Externí odkaz:
https://doaj.org/article/c310883b35e4439bb8c239e457ff84d1
Publikováno v:
Journal of Pharmacological Sciences, Vol 93, Iss 3, Pp 234-241 (2003)
ABSTRACT: Since voltage-sensitive dyes (VSDs) change their optical properties in response to membrane potential changes, non-invasive optical measurements of membrane excitation using VSDs have been applied to various types of excitable tissue. This
Externí odkaz:
https://doaj.org/article/796dfba58f6a4dbc9af9078ab003fce0
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85790 (2014)
How is binocular motion information integrated in the bilateral network of wide-field motion-sensitive neurons, called lobula plate tangential cells (LPTCs), in the visual system of flies? It is possible to construct an accurate model of this network
Externí odkaz:
https://doaj.org/article/645fb9d9432640c98706a1c62ac91ff4
Autor:
Jeonghyeon Yoon, Eriko Matsuo, Daichi Yamada, Hiroshi Mizuno, Takako Morimoto, Hiroyoshi Miyakawa, Setsuo Kinoshita, Hiroshi Ishimoto, Azusa Kamikouchi
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74289 (2013)
During courtship, many animals, including insects, birds, fish, and mammals, utilize acoustic signals to transmit information about species identity. Although auditory communication is crucial across phyla, the neuronal and physiologic processes are
Externí odkaz:
https://doaj.org/article/e318d33deda3430a867c4e5f965d6fdf
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50232 (2012)
For the purpose of elucidating the neural coding process based on the neural excitability mechanism, researchers have recently investigated the relationship between neural dynamics and the spike triggered stimulus ensemble (STE). Ermentrout et al. an
Externí odkaz:
https://doaj.org/article/84f0d6cd48444cd0bde698e59bb9b8c4
Autor:
Toru Aonishi, Ryoichi Maruyama, Tsubasa Ito, Hiroyoshi Miyakawa, Masanori Murayama, Keisuke Ota
Publikováno v:
Neuroscience research.
The rapid progress of imaging devices such as two-photon microscopes has made it possible to measure the activity of thousands to tens of thousands of cells at single-cell resolution in a wide field of view (FOV) data. However, it is not possible to