Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Hiroyasu Tsukaguchi"'
Autor:
Hiroko Ueda, Quynh Thuy Huong Tran, Linh Nguyen Truc Tran, Koichiro Higasa, Yoshiki Ikeda, Naoyuki Kondo, Masaki Hashiyada, Chika Sato, Yoshinori Sato, Akira Ashida, Saori Nishio, Yasunori Iwata, Hiroyuki Iida, Daisuke Matsuoka, Yoshihiko Hidaka, Kenji Fukui, Suzu Itami, Norihito Kawashita, Keisuke Sugimoto, Kandai Nozu, Motoshi Hattori, Hiroyasu Tsukaguchi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-25 (2023)
Abstract Focal segmental glomerulosclerosis (FSGS) is a common glomerular injury leading to end-stage renal disease. Monogenic FSGS is primarily ascribed to decreased podocyte integrity. Variants between residues 184 and 245 of INF2, an actin assembl
Externí odkaz:
https://doaj.org/article/94c4d236e2f54f2e8871e16fe0cc36df
Autor:
Linh Tran Nguyen Truc, Satoshi Matsuda, Akiko Takenouchi, Quynh Tran Thuy Huong, Yui Kotani, Tatsuhiko Miyazaki, Hiroaki Kanda, Katsuhiko Yoshizawa, Hiroyasu Tsukaguchi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Polycystic kidney disease (PKD) is a common genetic disorder arising from developmental and postnatal processes. Defects in primary cilia and their signaling (eg, mTOR) underlie the pathogenesis. However, how mTOR regulates tubular integrity
Externí odkaz:
https://doaj.org/article/9f40ecc5fac241f3bd660204f929c27e
Autor:
Yoshinori Sato, Hiroyasu Tsukaguchi, Koichiro Higasa, Naoto Kawata, Kiyoko Inui, Tran Nguyen Truc Linh, Tran Thuy Huong Quynh, Inoue Yoshihiko, Fumihiko Koiwa, Ashio Yoshimura
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Although most IgAN cases are sporadic, few show a familial aggregation. However, the prevalence and prognosis of IgAN individuals with positive famili
Externí odkaz:
https://doaj.org/article/4d51439a482d4421a2539bb4365973b0
Autor:
Daisuke Matsuoka, Shunsuke Noda, Motoko Kamiya, Yoshihiko Hidaka, Hisashi Shimojo, Yasushi Yamada, Tsutomu Miyamoto, Kandai Nozu, Kazumoto Iijima, Hiroyasu Tsukaguchi
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Mutations in the Wilms tumor 1 gene cause a spectrum of podocytopathy ranging from diffuse mesangial sclerosis to focal segmental glomerulosclerosis. In a considerable fraction of patients with Wilms tumor 1 mutations, the distinc
Externí odkaz:
https://doaj.org/article/1920d97ae3b645d5b775b2a825d52d71
Autor:
Tomohito Saito, MD, PhD, Mistuaki Ishida, MD, PhD, Makiko Kusabe, MD, Takahiro Utsumi, MD, Natsumi Maru, MD, Hiroshi Matsui, MD, Yohei Taniguchi, MD, PhD, Takayasu Kurata, MD, PhD, Hiroaki Kurokawa, MD, PhD, Takanobu Imada, MD, PhD, Koji Tsuta, MD, PhD, Hiroyasu Tsukaguchi, MD, PhD, Tomohiro Murakawa, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 8, Pp 100204- (2021)
Hypercalcemia is a common electrolyte abnormality in malignancy and is largely caused by activation of parathyroid hormone (PTH) pathways. We report the case of a 76-year-old man with hypercalcemia primarily owing to 1,25-dihydroxyvitamin D3 overprod
Externí odkaz:
https://doaj.org/article/d745569c598847058fdb27c15b1b70b6
Autor:
Hye Sun Hyun, Seong Heon Kim, Eujin Park, Myung Hyun Cho, Hee Gyung Kang, Hyun Soon Lee, Noriko Miyake, Naomichi Matsumoto, Hiroyasu Tsukaguchi, Hae Il Cheong
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-6 (2018)
Abstract Background Galloway–Mowat syndrome (GAMOS) is a rare hereditary renal–neurological disease characterized by early-onset steroid-resistant nephrotic syndrome in combination with microcephaly and brain anomalies. Recently, novel causative
Externí odkaz:
https://doaj.org/article/3cac33e472714d7697b7d04e6988ffcd
Autor:
Shazia Ashraf, Hiroki Kudo, Jia Rao, Atsuo Kikuchi, Eugen Widmeier, Jennifer A. Lawson, Weizhen Tan, Tobias Hermle, Jillian K. Warejko, Shirlee Shril, Merlin Airik, Tilman Jobst-Schwan, Svjetlana Lovric, Daniela A. Braun, Heon Yung Gee, David Schapiro, Amar J. Majmundar, Carolin E. Sadowski, Werner L. Pabst, Ankana Daga, Amelie T. van der Ven, Johanna M. Schmidt, Boon Chuan Low, Anjali Bansal Gupta, Brajendra K. Tripathi, Jenny Wong, Kirk Campbell, Kay Metcalfe, Denny Schanze, Tetsuya Niihori, Hiroshi Kaito, Kandai Nozu, Hiroyasu Tsukaguchi, Ryojiro Tanaka, Kiyoshi Hamahira, Yasuko Kobayashi, Takumi Takizawa, Ryo Funayama, Keiko Nakayama, Yoko Aoki, Naonori Kumagai, Kazumoto Iijima, Henry Fehrenbach, Jameela A. Kari, Sherif El Desoky, Sawsan Jalalah, Radovan Bogdanovic, Nataša Stajić, Hildegard Zappel, Assel Rakhmetova, Sharon-Rose Wassmer, Therese Jungraithmayr, Juergen Strehlau, Aravind Selvin Kumar, Arvind Bagga, Neveen A. Soliman, Shrikant M. Mane, Lewis Kaufman, Douglas R. Lowy, Mohamad A. Jairajpuri, Richard P. Lifton, York Pei, Martin Zenker, Shigeo Kure, Friedhelm Hildebrandt
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nephrotic syndrome is the second most common chronic kidney disease but there are no targeted treatment strategies available. Here the authors identify mutations of six genes codifying for proteins involved in cytoskeleton remodelling and modulation
Externí odkaz:
https://doaj.org/article/5fa7365ce28f4895a98f2773a190db3e
Autor:
Jiro Kino, Hiroyasu Tsukaguchi, Takahisa Kimata, Huan Thanh Nguyen, Yorika Nakano, Noriko Miyake, Naomichi Matsumoto, Kazunari Kaneko
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-7 (2017)
Abstract Background Congenital nephrotic syndrome (CNS) is a rare disorder caused by various structural and developmental defects of glomeruli. It occurs typically as an isolated kidney disorder but associates sometimes with other systemic, extrarena
Externí odkaz:
https://doaj.org/article/31642c12ed9e4e9881328e01a04a75b5
Autor:
Kazuma Sugie, Hirofumi Komaki, Nobuyuki Eura, Tomo Shiota, Kenji Onoue, Hiroyasu Tsukaguchi, Narihiro Minami, Megumu Ogawa, Takao Kiriyama, Hiroshi Kataoka, Yoshihiko Saito, Ikuya Nonaka, Ichizo Nishino
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3507 (2018)
Danon disease, an X-linked dominant cardioskeletal myopathy, is caused by primary deficiency of lysosome-associated membrane protein-2 (LAMP-2). To clarify the clinicopathological features and management, we performed the first nationwide, questionna
Externí odkaz:
https://doaj.org/article/742fb0dcd0274ccc803e63edd9982cb5
Autor:
Jiro Kin, Hiroyasu Tsukaguchi, Takahisa Kimata, Huan Thanh Nguyen, Yorika Nakano, Noriko Miyake, Naomichi Matsumoto, Kazunari Kaneko
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-2 (2017)
Externí odkaz:
https://doaj.org/article/19cc5f64e1f54de1a953442255419cac