Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hiroyasu Toriyama-Baba"'
Autor:
Hiroyuki Tsuda, Hiroyasu Toriyama-Baba, Akane Suzuki, Hiroshi Nomoto, Akihiro Naito, Shinobu Ueda, Makoto Asamoto
Publikováno v:
Cancer Science. 95:399-403
In order to clarify the susceptibility of the Hras128 rat harboring copies of the human c-Ha-ras proto-oncogene to 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), Hras128 rats were intragastically treated with 100 mg/kg PhIP 8 times (females)
Autor:
Tetsuya Hamaguchi, Yoichiro Matsuoka, Hiroki Yoshida, Katsumi Fukamachi, Hiroyuki Tsuda, Hiroaki Kawaguchi, Masato Kusunoki, Hiroyasu Toriyama-Baba
Publikováno v:
Toxicologic Pathology. 31:632-637
For comparison of mammary gland whole mounts with examination of 2 histologic sections of mammary gland, 56 Hras128 rats were intravenously injected with 50 mg/kg body weight of N-methyl- N-nitrosourea at 50 days of age and then sacrificed at days 5,
Autor:
Teruaki Iwamoto, Kotaro Hirai, Masaaki Terada, Yasushi Takahama, Hideo Sasaki, Hiromi Sakamoto, Tadao Kakizoe, Hiroyasu Toriyama-Baba, Takahiro Ochiya, Shoujiro Tamamushi, Hanako Yamamoto, Izumu Saito
Publikováno v:
Oncogene. 21:899-908
We previously demonstrated expression of the HST-1/FGF-4 gene in the testis of normal adult animals, which suggests its possible role in spermatogenesis. For an understanding of its functional significance in the testis, conditional transgene express
Autor:
Takahiro Ochiya, Hiroyasu Toriyama-Baba, Hiroyuki Tsuda, Tomonori Ota, Akihiro Naito, Takamasa Ohnishi, Makoto Asamoto, Akira Ando
Publikováno v:
Japanese Journal of Cancer Research : Gann
A transgenic rat line carrying three copies of the human c-Ha-ras proto-oncogene, including its own promoter region, has been established in our laboratory (Hras128 rats), and shown to be highly susceptible to induction of mammary and urinary bladder
Autor:
Takao Sekiya, Takahiro Ochiya, Masaaki Terada, Tomonori Ota, Hiroyasu Toriyama-Baba, Makoto Asamoto, Fumi Yamamoto, Hideyuki Akaza, Hiroyuki Tsuda, Yoichiro Matsuoka
Publikováno v:
Carcinogenesis. 21:1391-1396
greater in Hras128 rats than in their wild-type counterreported in 5–18% of human bladder cancer cases (18–20), parts. The numbers of carcinomas per rat were also significantly greater in Hras128 rats. Two cases of TCC while overexpression withou
Autor:
Hiroyuki Tsuda, Vladimir Krutovskikh, Samuel M. Cohen, Makoto Asamoto, Hiroyasu Toriyama-Baba
Publikováno v:
Japanese Journal of Cancer Research : Gann
We previously demonstrated a clear tendency for actively communicating rat bladder carcinoma cell lines with elevated expression of connexin 43 mRNA to possess strong tumorigenicity. In the present study, immunohistochemical analysis established that
Autor:
Hiroyasu Toriyama-Baba, Nobuo Takasuka, Hiroyuki Tsuda, Mitsuaki Maeda, Yoshio Iwahori, Makoto Asamoto, Vladimir Krutovskikh, Takaaki Hori
Publikováno v:
Japanese Journal of Cancer Research : Gann
We report here novel candidate chemopreventive agents active against experimental hepatocarcino‐genesis. The triazine derivatives 6‐(2‐chlorophenyl)‐2,4‐diamino‐l,3,5‐triazine (2CPDAT), 6‐(3‐chlorophenyl)‐2,4‐diamino‐l,3,5‐t
Autor:
Hanako, Yamamoto, Takahiro, Ochiya, Fumitaka, Takeshita, Hiroyasu, Toriyama-Baba, Kotaro, Hirai, Hideo, Sasaki, Hiroki, Sasaki, Hiromi, Sakamoto, Teruhiko, Yoshida, Izumu, Saito, Masaaki, Terada
Publikováno v:
Cancer research. 62(6)
Cyclin D1 is a critical gene involved in the regulation of progression through the G(1) phase of the cell cycle, thereby contributing to cell proliferation. Gene amplification and abnormal expression of Cyclin D1 have been described in several human
Autor:
Hiroyuki Tsuda, Hiroyasu Toriyama-Baba, Akihiro Naito, Tomonori Ota, Naomi Hokaiwado, Makoto Asamoto
Publikováno v:
Japanese Journal of Cancer Research : Gann
We have previously shown that transgenic rats carrying three copies of the human c-Ha-ras proto-oncogene (Hras128) are highly susceptible to N-methyl-N-nitrosourea (MNU) mammary carcinogenesis. All transgenic rats treated with 50 mg / kg MNU, i.v. at
Autor:
Hiroyuki Tsuda, Chikako Ishikawa, Tadao Kakizoe, Nobuo Takasuka, Makoto Asamoto, Eiji Araki, Kazunaga Yazawa, Masaaki Ligo, Hiroyasu Toriyama-Baba, Beom Seok Han, Yoshio Iwahori, Cheol Beom Park
Publikováno v:
Japanese Journal of Cancer Research : Gann
Organotropic chemopreventive effects of n–3 unsaturated fatty acids were studied using a multiorgan carcinogenesis model in male rats. Rats were treated with diethylnitrosamine (DEN), Nmethyl-N-nitrosourea (MNU), N-butyl-N-4-hydroxybutylnitrosamine