Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hiroyasu Nagahama"'
Autor:
Hideaki Naoe, Eisuke Kaku, Yumi Ido, Rika Gushima, Yoko Maki, Hirokazu Saito, Seiichiro Yokote, Ryosuke Gushima, Kouichi Nonaka, Yohmei Hoshida, Tetsuya Murao, Tetsu Ozaki, Kazunori Yokomine, Hideki Tanaka, Hiroyasu Nagahama, Kouichi Sakurai, Motohiko Tanaka, Ken-ichi Iyama, Hideo Baba, Yutaka Sasaki
Publikováno v:
Case Reports in Gastroenterology, Vol 5, Iss 3, Pp 583-589 (2011)
Metastasis of gastrointestinal stromal tumor (GIST) into the central nervous system is extremely rare. We report a patient with synchronous GIST and brain metastasis. At disease onset, there was left hemiplegia and ptosis of the right eyelids. Resect
Externí odkaz:
https://doaj.org/article/4bf9d78e7cec49d0bfed6d1ec4e5e36c
Autor:
Ken-ichi Iyama, Kazunori Yokomine, Hideaki Okajima, Fumio Tamura, Motohiko Tanaka, Kouichi Sakurai, Kimihiro Onoue, Yutaka Sasaki, Hideaki Naoe, Hideki Tanaka, Hiroyasu Nagahama, Yukihiro Inomata
Publikováno v:
Suizo. 27:69-79
症例は23歳，女性．膵体部に径40mmの造影効果のある腫瘍とびまん性に多発肝腫瘍を認め，肝腫瘍生検で非機能性高分化型膵内分泌癌と診断した．全身化学療法施行するも奏効が得られな
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d24feabc02260da6485c1a7b995f2ec
https://doi.org/10.2958/suizo.27.69
https://doi.org/10.2958/suizo.27.69
Autor:
Yutaka Sasaki, Hiroyasu Nagahama, Motohiko Tanaka, Yumi Ido, Ryosuke Gushima, Tetsu Ozaki, Rika Gushima, Kazunori Yokomine, Hideki Tanaka, Ken Ichi Iyama, Kouichi Sakurai, Tetsuya Murao, Yohmei Hoshida, Hideaki Naoe, Yoko Maki, Hideo Baba, Kouichi Nonaka, Eisuke Kaku, Hirokazu Saito, Seiichiro Yokote
Publikováno v:
Case Reports in Gastroenterology, Vol 5, Iss 3, Pp 583-589 (2011)
Case Reports in Gastroenterology
Case Reports in Gastroenterology
Metastasis of gastrointestinal stromal tumor (GIST) into the central nervous system is extremely rare. We report a patient with synchronous GIST and brain metastasis. At disease onset, there was left hemiplegia and ptosis of the right eyelids. Resect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efada18f7a89c7411d639cf5a829652e
http://www.karger.com/Article/FullText/333403
http://www.karger.com/Article/FullText/333403
Autor:
Motohiko Tanaka, Hiroshi Ashihara, Hiroyasu Nagahama, Yutaka Sasaki, Seishi Maeda, Masafumi Ikeda
Publikováno v:
Journal of Gastroenterology. 45:60-67
The aim of this study was to investigate the antitumor efficacy of treatment, identify prognostic factors, and construct a prognostic index in patients with hepatocellular carcinoma treated by transcatheter arterial infusion chemotherapy (TAI) using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e085cc9f7094a64655a07ffe57c711af
https://doi.org/10.1007/s00535-009-0109-8
https://doi.org/10.1007/s00535-009-0109-8
Autor:
Chikako Harada, Shinzo Nishi, Satoru Kase, Keiichi I. Nakayama, Hiromi Ikeda, Kazuhiko Yoshida, Shigeaki Ohno, Keiko Nakayama, Hiroyasu Nagahama, Kenji Shiratori, Junko Imaki, Kazuhiro Ohgami, Takayuki Harada
Publikováno v:
Anatomy and Embryology. 208:145-150
According to observations in various cell lines, elimination of the cyclin-dependent kinase inhibitor p27(KIP1) during the late G1 phase of the cell cycle is required for progression to the S phase. Eyes from C57BL/6 mice at embryonic days 13, 14, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944558401476ee18d4c164bd1d11ba93
https://doi.org/10.1007/s00429-004-0382-5
https://doi.org/10.1007/s00429-004-0382-5
Autor:
Satoshi Miyake, Shun-ichiro Iemura, Shigetsugu Hatakeyama, Noriko Ishida, Hiroyasu Nagahama, Keiichi I. Nakayama, Yohji A. Minamishima, Keiko Nakayama, Tohru Natsume, Masatoshi Kitagawa
Publikováno v:
Developmental Cell. 6:661-672
Although Skp2 has been thought to mediate the degradation of p27 at the G 1 -S transition, Skp2 −/− cells exhibit accumulation of p27 in S-G 2 phase with overreplication. We demonstrate that Skp2 −/− p27 −/− mice do not exhibit the overre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58488201a94b79c7e853b7460c1a6393
https://doi.org/10.1016/s1534-5807(04)00131-5
https://doi.org/10.1016/s1534-5807(04)00131-5
Autor:
Tadasuke Tsukiyama, Shigetsugu Hatakeyama, Akitomo Miyamoto, Sachiko Hirose, Hiroyuki Imaki, Yi Jiang, Keiko Nakayama, Masaaki Abe, Keiichi I. Nakayama, Hiroyasu Nagahama, Shigeo Ohno
Publikováno v:
Nature. 416:865-869
Protein kinase C (PKC), which comprises 11 closely related isoforms, has been implicated in a wide variety of cellular processes, such as growth, differentiation, secretion, apoptosis and tumour development. Among the PKC isotypes, PKC-delta is uniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b43490e42a78793ba42f6238deb4ef26
https://doi.org/10.1038/416865a
https://doi.org/10.1038/416865a
Autor:
Takashi Kanematsu, Norio Akaike, Keiko Nakayama, Miho Matsuda, Kiyoshi Hidaka, Kenji Yoshimura, Yoshio Misumi, Keiichi I. Nakayama, Tsuneyuki Yamamoto, Il Sung Jang, Hiroshi Takeuchi, Hiroyasu Nagahama, Taku Yamaguchi, Masato Hirata
Publikováno v:
The EMBO Journal. 21:1004-1011
The protein p130 was isolated from rat brain as an inositol 1,4,5-trisphosphate-binding protein with a domain organization similar to that of phospholipase C-delta1 but lacking PLC activity. We show that p130 plays an important role in signaling by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69517dc5a07cfb6b1d1d769dcd896dff
https://doi.org/10.1093/emboj/21.5.1004
https://doi.org/10.1093/emboj/21.5.1004
Autor:
Keiko Nakayama, Makoto Nakanishi, Kaoru Tominaga, Kyoji Ikeda, Hiroyuki Takai, Noboru Motoyama, Keiichi I. Nakayama, Hiroyasu Nagahama, Yohji A. Minamishima, Tadasuke Tsukiyama
Publikováno v:
Genes & Development. 14:1439-1447
The recent discovery of checkpoint kinases has suggested the conservation of checkpoint mechanisms between yeast and mammals. In yeast, the protein kinase Chk1 is thought to mediate signaling associated with the DNA damage checkpoint of the cell cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abc4a3582a3d82383b1f0c5820ffd5e1
https://doi.org/10.1101/gad.14.12.1439
https://doi.org/10.1101/gad.14.12.1439
Autor:
Noriko Ishida, Keiko Nakayama, Yohji A. Minamishima, Masaki Matsumoto, Hiroyasu Nagahama, Michiko Shirane, Masatoshi Kitagawa, Keiichi I. Nakayama, Ikuo Nakamichi, Tadasuke Tsukiyama, Shigetsugu Hatakeyama, Ryosuke Tsunematsu, Kyoko Kitagawa
Publikováno v:
Scopus-Elsevier
The ubiquitin-proteasome pathway plays an important role in control of the abundance of cell cycle regulators. Mice lacking Skp2, an F-box protein and substrate recognition component of an Skp1-Cullin-F-box protein (SCF) ubiquitin ligase, were genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9d9a1ef012d33d9b261de6c528c582
https://doi.org/10.1093/emboj/19.9.2069
https://doi.org/10.1093/emboj/19.9.2069