Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Hiroyasu Kinemuchi"'
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 155:266-271
Two mammalian monoamine oxidases (MAO), MAO-A and MAO-B, are similar in primary structures but have unique substrate/inhibitor selectivities. Carp (Cyprinus carpio) contains a MAO enzyme (C-MAO) with properties different from MAO-A and MAO-B. To dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d20d414da5a2b91b01ec652b7f281605
https://doi.org/10.1016/j.cbpb.2009.11.010
https://doi.org/10.1016/j.cbpb.2009.11.010
Autor:
Lars Oreland, Izuru Kakuta, Haruyo Sugimoto, Kazuya Takahashi, Toshio Obata, Hiroyasu Kinemuchi
Publikováno v:
Life Sciences. 80:1094-1099
We have previously reported that carp (Cyprinus carpio) tissue mitochondria contain a novel form of monoamine oxidase (MAO), which belongs neither to MAO-A nor to MAO-B of the mammalian enzyme. This conclusion results from the findings that the carp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a90b361b11ac77c12e7943f96ceddf2
https://doi.org/10.1016/j.lfs.2006.11.050
https://doi.org/10.1016/j.lfs.2006.11.050
Publikováno v:
NeuroToxicology. 25:325-335
Semicarbazide-sensitive amine oxidase (SSAO, EC 1.4.3.6) is a group of enzymes highly sensitive to inhibition by semicarbazide. This high sensitivity distinguishes these enzymes from monoamine oxidase (MAO). Various mammalian tissues contain membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ec5ad0b15429bf32390a544f9cd57f
https://doi.org/10.1016/s0161-813x(03)00118-9
https://doi.org/10.1016/s0161-813x(03)00118-9
Publikováno v:
Biogenic Amines. 17:1-14
Free radical production might make a major contribution at certain stages in the progression of injury to the brain. Oxygen free radical formation has been implicated in lesions caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and iron.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61b7166389d53a8bbefe29516dcb77fa
https://doi.org/10.1163/15693910260519256
https://doi.org/10.1163/15693910260519256
Autor:
Hajime Yasuhara, Hiroyasu Kinemuchi, Osamu Nakagawasai, Ryoo Taniguchi, Yuichiro Arai, Takeshi Tadano, Koichi Tan-No, Soichi Hozumi, Fukie Niijima, Takahiro Asao, Kensuke Kisara
Publikováno v:
Life Sciences. 69:1155-1166
We produced thiamine deficiency by treating mice with a thiamine deficient (TD) diet, but not with pyrithiamine, a thiamine antagonist. Twenty days after TD feeding, a significant antinociceptive effect was observed in the formalin test. A single inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40bb20f7065b4f880dffb427fbc8d6e2
https://doi.org/10.1016/s0024-3205(01)01207-3
https://doi.org/10.1016/s0024-3205(01)01207-3
Autor:
Kaori Takayanagi, Kensuke Kisara, Hiroyasu Kinemuchi, Yuichiro Arai, Naoyuki Kobayashi, Takeshi Tadano, Kazuya Takahashi, Lars Oreland
Publikováno v:
Archives of Biochemistry and Biophysics. 385:154-161
Various mammalian tissues contain membrane-bound amine oxidase termed semicarbazide-sensitive amine oxidase (SSAO). A variety of compounds has been identified as relatively selective SSAO inhibitors, but those inhibitors currently available also inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089e7b4f5f8b0f3daa5079f088c464b1
https://doi.org/10.1006/abbi.2000.2137
https://doi.org/10.1006/abbi.2000.2137
Autor:
Yuji Abe, Kensuke Kisara, Shinobu Sakurada, Tomoki Aizawa, Takahiro Asao, Yuichiro Arai, Ryuichiro Ando, Hiroyasu Kinemuchi, Takeshi Tadano, Akihiko Yonezawa
Publikováno v:
Brain Research. 696:21-29
During 30 days of thiamine deficiency (TD) feeding, the rat antinociceptive effect (pain threshold) to noxious heat stimulation was significantly increased in proportion to the decrease substance P (SP) fluorescent intensity in the spinal cord. Only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1867cbd09a995f3e9556fda2632748
https://doi.org/10.1016/0006-8993(95)00718-6
https://doi.org/10.1016/0006-8993(95)00718-6
Autor:
Yoshiteru Oshima, Takeshi Tadano, Yuichiro Arai, Anas Subarnas, Norimichi Nakahata, Hiroyasu Kinemuchi, Yasushi Ohizumi, Kensuke Kisara
Publikováno v:
Life Sciences. 52:289-296
A mechanism of antidepressant activity of beta-amyrin palmitate was studied using the forced swimming method in mice. Beta-amyrin palmitate (10 mg/kg) reduced the increase in the duration of immobility induced by tetrabenazine (100 and 200 mg/kg), bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909bc6135c5670aca48bc209b8e531b1
https://doi.org/10.1016/0024-3205(93)90220-w
https://doi.org/10.1016/0024-3205(93)90220-w
Publikováno v:
Neurochemistry international. 11(4)
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) has been shown to produce a condition resembling idiopathic Parkinson's disease in primates, with evidence of selective destruction of the nigrostriatal dopaminergic system. It is, however, rather l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779f0c12ce7edf7791873a8f75c51896
https://pubmed.ncbi.nlm.nih.gov/20501182
https://pubmed.ncbi.nlm.nih.gov/20501182
Autor:
Takeshi Tadano, Yuichiro Arai, Lars Oreland, Hiroyasu Kinemuchi, Kensuke Kisara, Masato Jinbo, Yoshie Toyoshima, Atsushi Tabata
Publikováno v:
Japanese Journal of Pharmacology. 83:164-166
Various mammalian tissues contain plasma membrane-bound amine oxidase, termed semicarbazide-sensitive amine oxidase (SSAO). In the present study, 2-bromoethylamine has been studied with regard to inhibitory properties towards tissue-bound SSAO in rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650f8a7b837084314894723a8d087adc
https://doi.org/10.1016/s0021-5198(19)30614-6
https://doi.org/10.1016/s0021-5198(19)30614-6