Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hiroyasu, Okazaki"'
Autor:
Seidai Sato, Shintaro Shinohara, Shinya Hayashi, Shun Morizumi, Shuichi Abe, Hiroyasu Okazaki, Yanjuan Chen, Hisatsugu Goto, Yoshinori Aono, Hirohisa Ogawa, Kazuya Koyama, Haruka Nishimura, Hiroshi Kawano, Yuko Toyoda, Hisanori Uehara, Yasuhiko Nishioka
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Nintedanib, a tyrosine kinase inhibitor that is specific for platelet-derived growth factor receptors (PDGFR), fibroblast growth factor receptors (FGFR), and vascular endothelial growth factor receptors (VEGFR), has recently been
Externí odkaz:
https://doaj.org/article/a844590c917a47219ecc7e5a1ef46e98
Autor:
Masami Kishi, Yoshinori Aono, Seidai Sato, Kazuya Koyama, Momoyo Azuma, Shuichi Abe, Hiroshi Kawano, Jun Kishi, Yuko Toyoda, Hiroyasu Okazaki, Hirohisa Ogawa, Hisanori Uehara, Yasuhiko Nishioka
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209786 (2018)
Platelet-derived growth factor (PDGF) has been implicated in the pathogenesis of pulmonary fibrosis. Nintedanib, a multi-kinase inhibitor that targets several tyrosine kinases, including PDGF receptor (PDGFR), was recently approved as an anti-fibroti
Externí odkaz:
https://doaj.org/article/cfb30fa817674314b43b83bf6305ec11
Autor:
Yoshio, Okano, Takashi, Yamasaki, Ryuichiro, Imai, Hiroyasu, Okazaki, Yuji, Higuchi, Tsutomu, Shinohara
Publikováno v:
Journal of Rural Medicine. 17:181-183
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3f7837873911d0b4782d0254263fce
https://doi.org/10.2185/jrm.2022-008
https://doi.org/10.2185/jrm.2022-008
Autor:
Seidai Sato, Hisanori Uehara, Shun Morizumi, Kazuya Koyama, Kozo Kagawa, Yuko Toyoda, Hirohisa Ogawa, Hiroyasu Okazaki, Yasuhiko Nishioka, Hiroshi Kawano, Haruka Nishimura, Hisatsugu Goto, Yajuan Chen
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 63:317-326
FGFs (fibroblast growth factors) are major factors associated with the pathogenesis of pulmonary fibrosis. On the one hand, nintedanib, a tyrosine kinase inhibitor targeting several growth factor r...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc5202b36d24c090828a996300e328e2
https://doi.org/10.1165/rcmb.2019-0090oc
https://doi.org/10.1165/rcmb.2019-0090oc
Autor:
Kazuya Koyama, Kozo Kagawa, Seidai Sato, Haruka Nishimura, Hiroshi Kawano, Hiroyasu Okazaki, Yuko Toyoda, Yasuhiko Nishioka, Hirohisa Ogawa, Shuichi Abe, Yajuan Chen, Momoyo Azuma, Shun Morizumi, Hisatsugu Goto, Hisanori Uehara, Yoshinori Aono, Hiroyuki Kouji
Publikováno v:
Experimental lung research. 45(7)
Purpose/Aim of the Study: Wnt/β-catenin signaling was reported to be activated in pulmonary fibrosis, and was focused on as a target for antifibrotic therapy. However, the mechanism how the inhibition of Wnt/β-catenin signaling ameliorate pulmonary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16e87b4a525a0ae4a75e1ecda910689
https://pubmed.ncbi.nlm.nih.gov/31298961
https://pubmed.ncbi.nlm.nih.gov/31298961
Autor:
Kazuya Koyama, Hisanori Uehara, Yoshinori Aono, Shuichi Abe, Hiroyasu Okazaki, Jun Kishi, Masami Kishi, Yuko Toyoda, Yasuhiko Nishioka, Hiroshi Kawano, Hirohisa Ogawa, Momoyo Azuma, Seidai Sato
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209786 (2018)
PLoS ONE
PLoS ONE
Platelet-derived growth factor (PDGF) has been implicated in the pathogenesis of pulmonary fibrosis. Nintedanib, a multi-kinase inhibitor that targets several tyrosine kinases, including PDGF receptor (PDGFR), was recently approved as an anti-fibroti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81fa57b2a4c369eebf6127cf0eea31a
https://doaj.org/article/cfb30fa817674314b43b83bf6305ec11
https://doaj.org/article/cfb30fa817674314b43b83bf6305ec11
Publikováno v:
Diffuse Parenchymal Lung Disease.
Background: IκB Kinase-β is a critical regulator in the activation of NF-κB, a transcription factor related to the expression and regulation of proinflammatory cytokines. Objective: To investigate whether inhibition IκB Kinase-β could ameliorate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad8f537f3585fd39a36f2bf22c0813ae
https://doi.org/10.1183/1393003.congress-2017.pa902
https://doi.org/10.1183/1393003.congress-2017.pa902
Autor:
Shuichi Abe, Yasuhiko Nishioka, Hisanori Uehara, Hiroyasu Okazaki, Yoshinori Aono, Hiroshi Kawano, Hirohisa Ogawa, Shinya Hayashi, Kazuya Koyama, Hisatsugu Goto, Shun Morizumi, Yanjuan Chen, Yuko Toyoda, Seidai Sato, Haruka Nishimura, Shintaro Shinohara
Publikováno v:
Respiratory Research
Respiratory Research, Vol 18, Iss 1, Pp 1-11 (2017)
Respiratory Research, Vol 18, Iss 1, Pp 1-11 (2017)
Background Nintedanib, a tyrosine kinase inhibitor that is specific for platelet-derived growth factor receptors (PDGFR), fibroblast growth factor receptors (FGFR), and vascular endothelial growth factor receptors (VEGFR), has recently been approved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c26667f7d37176e2aea7a70f0b274d
http://europepmc.org/articles/PMC5603061
http://europepmc.org/articles/PMC5603061
Autor:
Shun Morizumi, Seidai Sato, Kazuya Koyama, Hiroyasu Okazaki, Yajuan Chen, Hisatsugu Goto, Kozo Kagawa, Hirohisa Ogawa, Haruka Nishimura, Hiroshi Kawano, Yuko Toyoda, Hisanori Uehara, Yasuhiko Nishioka
Publikováno v:
American Journal of Respiratory Cell & Molecular Biology; Sep2020, Vol. 63 Issue 3, p317-326, 10p
Autor:
Hisatsugu Goto, Shuichi Abe, Hirohisa Ogawa, Yasuhiko Nishioka, Hisanori Uehara, Hiroyasu Okazaki, Yanjuan Chen, Yoshinori Aono, Masaki Hanibuchi, Shun Morizumi, Seidai Sato
Publikováno v:
1.5 Diffuse Parenchymal Lung Disease.
[Introduction] Nintedanib is a tyrosine kinase inhibitor specific for fibroblast growth factor (FGF) receptor, platelet-derived growth factor (PDGF) receptor, and vascular endothelial growth factor receptor. Recently, one-year treatment with nintedan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1806588613d2f96f239e63a1878a6d4
https://doi.org/10.1183/13993003.congress-2016.pa778
https://doi.org/10.1183/13993003.congress-2016.pa778