Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hiroya Sakuma"'
Autor:
Honggang Ye, Maria M. Sutanto, Hiroya Sakuma, Kelly K. Ferguson, Matthew J. Brady, Ronald N. Cohen
Publikováno v:
Journal of Biological Chemistry. 285:18485-18495
The silencing mediator of retinoid and thyroid hormone receptors (SMRT) serves as a corepressor for nuclear receptors and other factors. Recent evidence suggests that SMRT is an important regulator of metabolism, but its role in adipocyte function in
Publikováno v:
Diabetes Research and Clinical Practice. 84:19-26
Hepatocyte nuclear factor (HNF)-1alpha is a homeodomain-containing transcription factor. Humans heterozygous for mutations in the HNF-1alpha gene develop maturity-onset diabetes of the young (MODY3), which is associated with reduced insulin secretion
Autor:
Yoshiyuki Natsume, Masayoshi Ishizawa, Yoritsuna Yamamoto, Yasunori Kawai, Keigo Yasuda, Atsushi Miura, Kazuo Kajita, Hiroya Sakuma, Tatsuo Ishizuka, Yoshinori Kanoh
Publikováno v:
Metabolism. 52:19-24
Ceramide has been confirmed to be a signal mediator of apoptosis that is induced by tumor necrosis factor-alpha (TNF-alpha). It has also been reported that ceramide may induce insulin resistance as well as TNF-alpha. We investigated the effect of cer
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 63
Publikováno v:
American journal of physiology. Cell physiology. 283(2)
Cardiovascular disease is a serious complication in diabetic patients. To elucidate the precise mechanisms of atherosclerosis in diabetic patients, the effects of high glucose concentration (25 mM) on apoptosis regulation and bcl-2 family protein exp
Autor:
Kazuo Kajita, Masayoshi Ishizawa, Yoshinori Kanoh, Hiroya Sakuma, Tatsuo Ishizuka, Atsushi Miura, Keigo Yasuda, Mika Kimura, Hiroyuki Morita, Takeshi Suzuki
Publikováno v:
Cellular signalling. 12(4)
It has been reported that pertussis toxin (PTX) suppresses the function of trimeric guanine nucleotide binding protein (G-protein). We examined the effect of PTX on insulin-induced glucose uptake, diacylglycerol (DG)-protein kinase C (PKC) signalling
Publikováno v:
The Proceedings of the Materials and processing conference. :422-1
Autor:
Toshio Katoh, Hiroya Sakuma, Takahiro Sawamura, Osami Daimaru, Takeo Nakakita, Arizumi Kikuchi, Shinichi Itoh, Yuko Wakayama
Publikováno v:
American Journal of Clinical Pathology. 138:A069-A069
Autor:
Shoichiro Yoshihara, Hiroya Sakuma
Publikováno v:
The Proceedings of the Materials and processing conference. :929-1
Autor:
Mayumi Yamamoto, Hiroya Sakuma, Mie Okumura, Denise R. Cooper, Keigo Yasuda, Toshihiro Kojima
Publikováno v:
Diabetes Research and Clinical Practice. 50:155