Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hiroya Kitsunai"'
Autor:
Takao Takiyama, Toshihiro Sera, Masanori Nakamura, Masato Hoshino, Kentaro Uesugi, Shin-ichi Horike, Makiko Meguro-Horike, Ryoichi Bessho, Yuri Takiyama, Hiroya Kitsunai, Yasutaka Takeda, Kazuki Sawamoto, Naoto Yagi, Yuji Nishikawa, Yumi Takiyama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-24 (2022)
Abstract Maternal overnutrition affects offspring susceptibility to nonalcoholic steatohepatitis (NASH). Male offspring from high-fat diet (HFD)-fed dams developed a severe form of NASH, leading to highly vascular tumor formation. The cancer/testis a
Externí odkaz:
https://doaj.org/article/238916917a03478ca7f283a0edbc44a6
Autor:
Tomoe Abe, Yasutaka Takeda, Takao Takiyama, Ayaka Sasaki, Ryoichi Bessho, Mao Sato, Hiroya Kitsunai, Hidemitsu Sakagami, Atsuko Abiko, Koji Imai, Sayaka Yuzawa, Mishie Tanino, Yumi Takiyama
Publikováno v:
Clinical Case Reports, Vol 9, Iss 4, Pp 1991-1998 (2021)
Abstract The diagnosis of insulinoma in perinatal women can be difficult, as hypoglycemic symptoms may be masked by pregnancy‐associated insulin resistance. In addition, when multiple insulinomas are observed, it is necessary to consider the possib
Externí odkaz:
https://doaj.org/article/3289f77211144946b343394dbe2a9448
Autor:
Yumi Takiyama, Toshihiro Sera, Masanori Nakamura, Kanaki Ishizeki, Yasuaki Saijo, Tsuyoshi Yanagimachi, Manami Maeda, Ryoichi Bessho, Takao Takiyama, Hiroya Kitsunai, Hidemitsu Sakagami, Daisuke Fujishiro, Yukihiro Fujita, Yuichi Makino, Atsuko Abiko, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, Tsuguhito Ota, Masakazu Haneda
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 329-346 (2018)
Background: Recent large-scale clinical studies demonstrate that sodium-glucose cotransporter 2 (SGLT2) inhibitors protect the diabetic kidney. However, clinical and animal studies have not shown the changes of the total glomeruli in the whole kidney
Externí odkaz:
https://doaj.org/article/e0c854294846408e9992931b31f45d40
Autor:
Tsuyoshi Yanagimachi, Yukihiro Fujita, Yasutaka Takeda, Jun Honjo, Hidemitsu Sakagami, Hiroya Kitsunai, Yumi Takiyama, Atsuko Abiko, Yuichi Makino, Timothy J. Kieffer, Masakazu Haneda
Publikováno v:
Molecular Metabolism, Vol 6, Iss 2, Pp 226-231 (2017)
Objective: Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) possess multiple bioactive isoforms that are rendered non-insulinotropic by the enzyme dipeptidyl peptidase-4 (DPP-4). Recently, some ELISA kits have be
Externí odkaz:
https://doaj.org/article/4cfa0b178d4546af941392b8be0dd0fc
Autor:
Ayaka Sasaki, Tomoe Abe, Atsuko Abiko, Mishie Tanino, Yumi Takiyama, Hiroya Kitsunai, Mao Sato, Ryoichi Bessho, Koji Imai, Yasutaka Takeda, Hidemitsu Sakagami, Takao Takiyama, Sayaka Yuzawa
Publikováno v:
Clinical Case Reports
Clinical Case Reports, Vol 9, Iss 4, Pp 1991-1998 (2021)
Clinical Case Reports, Vol 9, Iss 4, Pp 1991-1998 (2021)
The diagnosis of insulinoma in perinatal women can be difficult, as hypoglycemic symptoms may be masked by pregnancy‐associated insulin resistance. In addition, when multiple insulinomas are observed, it is necessary to consider the possibility not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa59fdb2cc56b0c46461974259e0270
http://europepmc.org/articles/PMC8077346
http://europepmc.org/articles/PMC8077346
Autor:
Tomoe Abe, Yasutaka Takeda, Ichiro Sakuma, Mizuho Okada, Ayaka Sasaki, Ryoichi Bessho, Mao Sato, Hiroya Kitsunai, Yumi Takiyama, Masaru Sakurai
Background: This study was aimed to compare the efficacy of two combination tablets of DPP-4 inhibitors and metformin with different dosages, alogliptin/metformin (AM) and vildagliptin/metformin (VM), on glycemic control in patients with type 2 diabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6928912f91ba619bb50f80662a17054
https://doi.org/10.21203/rs.3.rs-1692675/v1
https://doi.org/10.21203/rs.3.rs-1692675/v1
Autor:
Shin-Ichi Horike, Ryoichi Bessho, Yumi Takiyama, Masanori Nakamura, Takao Takiyama, Toshihiro Sera, Yuji Nishikawa, Hiroya Kitsunai, Hidemitsu Sakagami, Yasutaka Takeda
Publikováno v:
Diabetes. 70
We investigated whether overnutrition during pregnancy were associated with the changes in gene expressions, oxygen metabolism, and vascular and hepatic parenchymal remodeling in fetal livers at mid gestational days E14.5 of dams fed a control diet (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::801e9abe6ae8a2315aadbbd6e82ce4c8
https://doi.org/10.2337/db21-1171-p
https://doi.org/10.2337/db21-1171-p
Autor:
Suratsawadee Promsuwan, Ryoichi Bessho, Takao Takiyama, Yumi Takiyama, Hiroya Kitsunai, Kazuki Sawamoto, Yasutaka Takeda
Publikováno v:
Diabetes. 70
Recent study has demonstrated the Nrf2 (NF-E2-related factor 2) activator bardoxolone methyl improved renal function in diabetic kidney disease (DKD). On the other hand, mitochondrial transcription factor A (TFAM) activation inhibits mitochondrial DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3593b798cb46326f9b214e2ca4ce6c25
https://doi.org/10.2337/db21-391-p
https://doi.org/10.2337/db21-391-p
Autor:
Hiroya Kitsunai, Naoki Nakagawa, Naoyuki Hasebe, Atsutaka Okizaki, Masakazu Haneda, Yumi Takiyama
Publikováno v:
Diabetes. 70
Renal damage in diabetic nephropathy (DN) is evaluated by biochemical tests such as urine albumin-to-creatinine ratio (UACR) and serum estimated glomerular filtration rate (eGFR). On the other hand, renal biopsy, which is rich in definitive informati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94455d739ff110808fb61cd71a60e8e2
https://doi.org/10.2337/db21-414-p
https://doi.org/10.2337/db21-414-p
Autor:
Yasutaka Takeda, Yukihiro Fujita, Atsuko Abiko, Timothy J. Kieffer, Hiroya Kitsunai, Yumi Takiyama, Tsuyoshi Yanagimachi, Masakazu Haneda, Jun Honjo, Hidemitsu Sakagami, Yuichi Makino
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 2, Pp 226-231 (2017)
Molecular Metabolism, Vol 6, Iss 2, Pp 226-231 (2017)
Objective Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) possess multiple bioactive isoforms that are rendered non-insulinotropic by the enzyme dipeptidyl peptidase-4 (DPP-4). Recently, some ELISA kits have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff59bc746af167d69b826a2bc030cf96
https://doi.org/10.1016/j.molmet.2016.12.009
https://doi.org/10.1016/j.molmet.2016.12.009