Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Hiroya KOBAYASHI"'
Autor:
Aiko Murai, Terufumi Kubo, Takayuki Ohkuri, Junko Yanagawa, Yuki Yajima, Akemi Kosaka, Dongliang Li, Toshihiro Nagato, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Takeshi Nagasaki, Yoshihiko Hirohashi, Hiroya Kobayashi, Toshihiko Torigoe
Publikováno v:
Immunological Medicine, Vol 47, Iss 2, Pp 93-99 (2024)
AbstractThe recognition by cytotoxic T cells (CTLs) is essential for the clearance of SARS-CoV-2 virus-infected cells. Several viral proteins have been described to be recognized by CTLs. Among them, the spike (S) protein is one of the immunogenic pr
Externí odkaz:
https://doaj.org/article/df5db71fc3a644528e48fd8244c2f187
Autor:
Emi Qian, Masahiro Uemura, Hiroya Kobayashi, Shiho Nakamura, Fumiko Ozawa, Sho Yoshimatsu, Mitsuru Ishikawa, Osamu Onodera, Satoru Morimoto, Hideyuki Okano
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-10 (2023)
Abstract Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is an inherited cerebral small vessel disease (CSVD) caused by biallelic mutations in the high-temperature requirement serine peptidase A1
Externí odkaz:
https://doaj.org/article/f2d5916618a74664bb6b7b4455d350a4
Autor:
Yuki Yajima, Akemi Kosaka, Takayuki Ohkuri, Yoshihiko Hirohashi, Dongliang Li, Takeshi Nagasaki, Toshihiro Nagato, Toshihiko Torigoe, Hiroya Kobayashi
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e20192- (2023)
The current coronavirus disease 2019 (COVID-19) pandemic that is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a significant threat to public health. Although vaccines based on the mRNA of the SARS-CoV-2 spike protein
Externí odkaz:
https://doaj.org/article/560abae92ccf4155996ccf9b1e1e8b8c
Publikováno v:
Fibers, Vol 11, Iss 12, p 107 (2023)
Easy maintenance and high durability are expected in structures made with fiber-reinforced cementitious composite (FRCC) reinforced with fiber-reinforced polymer (FRP) bars. In this study, we focused on the bond and cracking characteristics of polyvi
Externí odkaz:
https://doaj.org/article/8384650b25ae49e6a1758ff7f7be9bfe
Autor:
Yukari Sakurai, Naohisa Toriumi, Takeo Sarashina, Toru Ishioka, Marino Nagata, Hiroya Kobayashi, Hiroshi Azuma
Publikováno v:
Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-6 (2022)
Abstract Background Hereditary folate malabsorption—a rare disorder caused by impairment of the folate transporter—can develop into severe folate deficiency manifesting as megaloblastic anemia and occasionally thrombocytopenia. Reportedly, megalo
Externí odkaz:
https://doaj.org/article/3a86337c070644dd82a66d4eb4dfeee2
Autor:
Michihisa Kono, Hiroki Komatsuda, Hidekiyo Yamaki, Takumi Kumai, Ryusuke Hayashi, Risa Wakisaka, Toshihiro Nagato, Takayuki Ohkuri, Akemi Kosaka, Kenzo Ohara, Kan Kishibe, Miki Takahara, Akihiro Katada, Tatsuya Hayashi, Hiroya Kobayashi, Yasuaki Harabuchi
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Fibroblast growth factor receptor 1 (FGFR1) is overexpressed in multiple types of solid tumors, including head and neck squamous cell carcinoma (HNSCC). Being associated with poor prognosis, FGFR1 is a potential therapeutic target for aggressive tumo
Externí odkaz:
https://doaj.org/article/5129a649e75a4c4abc551cc79d5a4892
Autor:
Shiho Kaneko, Kana Matsuda, Yasuko Mizuta, Shoya Shiratori, Kazuma Kishi, Akihisa Nakamura, Masataka Yagisawa, Nobuyuki Ehira, Minoru Uebayashi, Hiroya Kobayashi
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-6 (2021)
Abstract Background Olmesartan, which is an angiotensin II receptor blocker, reportedly causes spruelike enteropathy, with intestinal villous atrophy as its typical histopathological finding. Interestingly, collagenous and/or lymphocytic gastritis an
Externí odkaz:
https://doaj.org/article/39584405db714a4f8cd357966d1817ce
Autor:
Hidefumi Sako, Kazuhiro Omori, Masaaki Nakayama, Hiroki Mandai, Hidetaka Ideguchi, Saki Yoshimura-Nakagawa, Kyosuke Sakaida, Chiaki Nagata-Kamei, Hiroya Kobayashi, Satoki Ishii, Mitsuaki Ono, Soichiro Ibaragi, Tadashi Yamamoto, Seiji Suga, Shogo Takashiba
Publikováno v:
Journal of Fungi, Vol 9, Iss 3, p 314 (2023)
Current periodontal treatment focuses on the mechanical removal of the source of infection, such as bacteria and their products, and there is no approach to control the host inflammatory response that leads to tissue destruction. In order to control
Externí odkaz:
https://doaj.org/article/4672e58e5ea34167a1c5663db5e9d277
Autor:
Kyosuke Sakaida, Kazuhiro Omori, Masaaki Nakayama, Hiroki Mandai, Saki Nakagawa, Hidefumi Sako, Chiaki Kamei, Satoshi Yamamoto, Hiroya Kobayashi, Satoki Ishii, Mitsuaki Ono, Soichiro Ibaragi, Keisuke Yamashiro, Tadashi Yamamoto, Seiji Suga, Shogo Takashiba
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Osteoporosis is a common disease characterized by a systemic impairment of bone mass and microarchitecture that results in fragility fractures. Severe bone loss due to osteoporosis triggers pathological fractures and consequently decreases the daily
Externí odkaz:
https://doaj.org/article/f24d66909031438e86501ee1721d6767
Autor:
Yui Hirata-Nozaki, Takayuki Ohkuri, Kenzo Ohara, Takumi Kumai, Marino Nagata, Shohei Harabuchi, Akemi Kosaka, Toshihiro Nagato, Kei Ishibashi, Kensuke Oikawa, Naoko Aoki, Mizuho Ohara, Yasuaki Harabuchi, Yuji Uno, Hidehiro Takei, Esteban Celis, Hiroya Kobayashi
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) originates from squamous epithelium of the upper aerodigestive tract and is the most common malignancy in the head and neck region. Among HNSCCs, oropharynx squamous cell carcinoma (OS
Externí odkaz:
https://doaj.org/article/3c9e9e4d83c24aa29d3cb2439f369956