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pro vyhledávání: '"Hirotsune Sasaki"'
Autor:
Eiko Tada, Kaori Toyomura, Hiroyuki Nakamura, Hirotsune Sasaki, Takeshi Saito, Masayuki Kaneko, Yasunobu Okuma, Toshihiko Murayama
Publikováno v:
Journal of Pharmacological Sciences, Vol 114, Iss 4, Pp 420-432 (2010)
Abstract.: Ceramide, a key molecule in the metabolism of sphingolipids, is converted by ceramidase to sphingosine, and phosphorylated by ceramide kinase to form ceramide-1-phosphate (C1P). In this study, we improved on a method of thin-layer chromato
Externí odkaz:
https://doaj.org/article/1750bccab989434593a4ff4bd6cc1f3e
Autor:
Kaori Toyomura, Hiroyuki Nakamura, Wataru Matsuzaki, Naoto Yamaguchi, Hirotsune Sasaki, Toshihiko Murayama, Aya Okamoto
Publikováno v:
Archives of biochemistry and biophysics.
Ceramidase hydrolyzes ceramide to fatty acids and sphingosine, and sphingosine is then converted to sphingosine-1-phosphate. Ceramide and sphingosine-1-phosphate act as signaling molecules. Although stimuli coupling to protein kinases-dependent syste
Autor:
Takeshi Saito, Kaori Toyomura, Masayuki Kaneko, Eiko Tada, Toshihiko Murayama, Yasunobu Okuma, Hiroyuki Nakamura, Hirotsune Sasaki
Publikováno v:
Journal of Pharmacological Sciences, Vol 114, Iss 4, Pp 420-432 (2010)
Ceramide, a key molecule in the metabolism of sphingolipids, is converted by ceramidase to sphingosine, and phosphorylated by ceramide kinase to form ceramide-1-phosphate (C1P). In this study, we improved on a method of thin-layer chromatography usin