Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Hirotsugu Yanai"'
Autor:
Katsuhiro Yoshikawa, Mitsuaki Ishida, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Cancer-associated fibroblasts (CAFs) are some of the most abundant components of the tumour microenvironment. A recent study suggested that in some cancers, CAFs express programmed death ligand 1 (PD-L1), which can act as a progno
Externí odkaz:
https://doaj.org/article/bf387e4ac97042ff936efbd811da52c0
Autor:
Katsuhiro Yoshikawa, Mitsuaki Ishida, Naoki Kan, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie
Publikováno v:
World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-8 (2020)
Abstract Background We aimed to investigate the usefulness of magnetic resonance imaging (MRI) and histopathological shrinkage patterns to formulate a predictive equation for estimating residual tumor size after neoadjuvant chemotherapy (NAC) in trip
Externí odkaz:
https://doaj.org/article/a99c71851ffb497c8015fff9636c9fe5
Autor:
Hirotsugu Yanai, Katsuhiro Yoshikawa, Mitsuaki Ishida, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0245725 (2021)
BackgroundStromal reaction is an important prognostic factor in several cancers, and the presence of myxoid change was assessed as a poor prognostic factor in colorectal cancer. However, the prognostic significance of myxoid change in triple-negative
Externí odkaz:
https://doaj.org/article/37ba1099303a4dfb8bf4fee68029e672
Autor:
Katsuhiro Yoshikawa, Mitsuaki Ishida, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253176 (2021)
IntroductionCD155 is an immune checkpoint protein. Its overexpression is an indicator of poor prognosis in some types of cancer. However, the significance of CD155 expression in patients with triple-negative breast cancer, and the relationship betwee
Externí odkaz:
https://doaj.org/article/e1b61ea326794a06b2b5eb3adb0bcee7
Autor:
Katsuhiro Yoshikawa, Mitsuaki Ishida, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257860 (2021)
BackgroundTriple-negative breast cancer (TNBC) is the most aggressive type of breast cancer. A recent study demonstrated the efficacy of anti-PD-L1 (anti-programmed death ligand-1) immunotherapy in patients with TNBC. However, the identification of T
Externí odkaz:
https://doaj.org/article/0312115e02ca406ba35c64337ec308fd
Autor:
Katsuhiro Yoshikawa, Mitsuaki Ishida, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242563 (2020)
Adipophilin is a lipid droplet-associated protein whose expression can act as a prognostic marker for specific cancers. Using immunohistochemical staining and tissue microarrays, we assayed the expression of adipophilin in 61 patients with triple-neg
Externí odkaz:
https://doaj.org/article/9db594db0f5049cd915d2f66ae256ea3
Autor:
Tatsuma Sakaguchi, Yoshinori Hamada, Yusuke Nakamura, Hiroshi Hamada, Takeshi Shirai, Hirotsugu Yanai, Masanori Kon
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 8, Iss C, Pp 22-26 (2016)
Congenital prepubic sinus (CPS) is an extremely rare anomaly, which is often associated with purulent discharge from a midline opening overlying the pubis. CPS was first described by Campbell et al. in 1987 and they suggested that it might represent
Externí odkaz:
https://doaj.org/article/3f7916352e7c4b1595bd5f56e9ecc486
Autor:
Katsuhiro Yoshikawa, Mitsuaki Ishida, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto, Tomoharu Sugie
Publikováno v:
Oncology letters. 23(4)
Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer. The present authors recently demonstrated that expression of the lipid-related protein adipophilin (ADP) in operative specimens is a significant poor prognostic factor
Autor:
Mitsugu Sekimoto, Tomoharu Sugie, Hirotsugu Yanai, Katsuhiro Yoshikawa, Koji Tsuta, Mitsuaki Ishida
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Cancer
BMC Cancer
Background Cancer-associated fibroblasts (CAFs) are some of the most abundant components of the tumour microenvironment. A recent study suggested that in some cancers, CAFs express programmed death ligand 1 (PD-L1), which can act as a prognostic mark
Autor:
Katsuhiro, Yoshikawa, Mitsuaki, Ishida, Hirotsugu, Yanai, Koji, Tsuta, Mitsugu, Sekimoto, Tomoharu, Sugie
Publikováno v:
Oncology Letters. 23
T-cell immunoglobulin mucin-3 (TIM-3) expressed at the T-cell surface acts as an immune checkpoint when bound by its ligand galectin-9. Blockade of immunosuppression by the TIM3/galectin-9 signalling pathway may offer novel therapeutic approaches for