Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hirotsugu Uehara"'
Autor:
Takashi Taida, Yuki Ohta, Jun Kato, Sadahisa Ogasawara, Yuhei Ohyama, Yukiyo Mamiya, Hayato Nakazawa, Ryosuke Horio, Chihiro Goto, Satsuki Takahashi, Akane Kurosugi, Michiko Sonoda, Wataru Shiratori, Tatsuya Kaneko, Yuya Yokoyama, Naoki Akizue, Yotaro Iino, Junichiro Kumagai, Hideaki Ishigami, Hirotaka Koseki, Kenichiro Okimoto, Keiko Saito, Masaya Saito, Tomoaki Matsumura, Tomoo Nakagawa, Shinichiro Okabe, Hirofumi Saito, Kazuki Kato, Hirotsugu Uehara, Hideaki Mizumoto, Yoshihiro Koma, Ryosaku Azemoto, Kenji Ito, Hidehiro Kamezaki, Yoshifumi Mandai, Yoshio Masuya, Yoshihiro Fukuda, Yoshio Kitsukawa, Haruhisa Shimura, Toshio Tsuyuguchi, Naoya Kato
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Many molecular targeted agents, including biologics, have emerged for inflammatory bowel diseases (IBD), but their high prices have prevented their widespread use. This study aimed to reveal the changes in patient characteristics and the the
Externí odkaz:
https://doaj.org/article/cb9d3bf198234cee83634445e2631f17
Autor:
Daisuke Fukushi, Keigo Murakami, Yuji Watanabe, Norihiko Sugimoto, Hirotsugu Uehara, Masafumi Seki
Publikováno v:
Infection and Drug Resistance. 15:1049-1054
Daisuke Fukushi,1 Keigo Murakami,2 Yuji Watanabe,3 Norihiko Sugimoto,4 Hirotsugu Uehara,4 Masafumi Seki5 1Division of Gastroenterology, Tohoku Medical and Pharmaceutical University Hospital, Sendai City, Miyagi, Japan; 2Division of Pathology, Tohoku
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21d2e6bbaf9d267ff86e55feba88da1
https://doi.org/10.2147/idr.s358112
https://doi.org/10.2147/idr.s358112
Publikováno v:
Kansenshogaku Zasshi. 91:752-758
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2399811de55600ad9a9a319e489c1077
https://doi.org/10.11150/kansenshogakuzasshi.91.752
https://doi.org/10.11150/kansenshogakuzasshi.91.752
Publikováno v:
Medicine
Multiple endocrine neoplasia type 1 (MEN1) is classically characterized by the development of functional or nonfunctional hyperplasia or tumors in endocrine tissues (parathyroid, pancreas, pituitary, adrenal). Because effective treatments have been d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f4cb000ccb0e147fca860bb1c3954b
https://doi.org/10.1097/md.0b013e3182954af1
https://doi.org/10.1097/md.0b013e3182954af1
Autor:
Nieves González, David H. Coy, Robert T. Jensen, Tomoo Nakagawa, Simon J. Hocart, Hirotsugu Uehara, Tatsuro Katsuno, Samuel A. Mantey
Publikováno v:
Biochemical Pharmacology. 84:936-948
There is increased interest in the Bn-receptor family because they are frequently over/ectopically expressed by tumors and thus useful as targets for imaging or receptor-targeted-cytotoxicity. The synthetic Bn-analog, [D-Tyr(6), β-Ala(11), Phe(13),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406c2eac05130707b2374097fad02ae7
https://doi.org/10.1016/j.bcp.2012.07.010
https://doi.org/10.1016/j.bcp.2012.07.010
Autor:
Veronica Sancho, Robert T. Jensen, Nieves González, Samuel A. Mantey, Hirotsugu Uehara, Tomoo Nakagawa, Tatsuro Katsuno
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 331:265-276
The mammalian bombesin (Bn) peptides, neuromedin B (NMB) and gastrin-releasing peptide (GRP), have widespread actions in many tissues, and their effects are mediated by two closely related G-protein-coupled receptors, the NMBR and GRPR. Little is kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1013f043b578ac669c9553e0fcd22605
https://doi.org/10.1124/jpet.109.154245
https://doi.org/10.1124/jpet.109.154245
Autor:
Hirotsugu Uehara, Shigeru Yamato, Takazumi Kimura, Kei Matsueda, Tsuyoshi Ishida, Hajime Ariga, Tomofumi Amano, Hisao Tajiri, Akira Torii
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 293:G903-G910
Corticotropin-releasing factor (CRF) and urocortin I (UcnI) have been shown to accelerate colonic transit after central nervous system (CNS) or peripheral administration, but the mechanism of their peripheral effect on colonic motor function has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5d5d7e1ec8d1249df14f9c45bce7aa
https://doi.org/10.1152/ajpgi.00066.2007
https://doi.org/10.1152/ajpgi.00066.2007
Autor:
Hajime Ariga, Ichiro Iizuka, Tomofumi Amano, Hirotsugu Uehara, Shigeru Yamato, Mamoru Hiraishi, Kei Matsueda
Publikováno v:
Progress of Digestive Endoscopy. 67:45-49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8e63501ce1881f44959bd6d473283bd
https://doi.org/10.11641/pde.67.2_45
https://doi.org/10.11641/pde.67.2_45
The role of pharmacotherapy in the management of patients with Zollinger-Ellison syndrome (ZES) is often equated with the medical management of acid hypersecretion. However, pharmacotherapy is also increasingly involved in the other management areas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3228302dc5e42dcf9199be0b533c3a1
https://europepmc.org/articles/PMC3580316/
https://europepmc.org/articles/PMC3580316/
Autor:
Hirotsugu Uehara, David H. Coy, Tapas K. Pradhan, Samuel A. Mantey, Robert T. Jensen, Bernardo Nuche-Berenguer, Veronica Sancho, Nieves González
The mammalian bombesin (Bn)-receptor family [gastrin-releasing peptide-receptor (GRPR-receptor), neuromedin B-receptor (NMB receptor)], their natural ligands, GRP/NMB, as well as the related orphan receptor, BRS-3, are widely distributed, and frequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba740c28939a1b8a51b7c9582af8d2d
http://hdl.handle.net/11568/882978
http://hdl.handle.net/11568/882978