Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hirotsugu Takano"'
Autor:
Tomoaki Inazumi, Naritoshi Shirata, Kazushi Morimoto, Hirotsugu Takano, Eri Segi-Nishida, Yukihiko Sugimoto
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 8, Pp 1500-1508 (2011)
The prostaglandin (PG) receptors EP4 and FP have the potential to exert negative effects on adipogenesis, but the exact contribution of endogenous PG-driven receptor signaling to this process is not fully understood. In this study, we employed an adi
Externí odkaz:
https://doaj.org/article/4575f152071848319364b86b4c9a04b5
Autor:
Ryota Hamasaki, Gary Kohanbash, Kazuhiko Takeda, Tohru Kotani, Hideho Okada, Hirotsugu Takano, Tomoko Yoshida
Publikováno v:
Cancer Research. 80:4443-4443
Prostaglandin E2 (PGE2) contributes to immunosuppression in the tumor microenvironment through one or more of its receptors (EP1-EP4), especially EP4 which is expressed at high levels on myeloid cells. ONO-4578/BMS-986310 is a novel EP4-selective ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17d406ce1f46787fa790a5e117712c86
https://doi.org/10.1158/1538-7445.am2020-4443
https://doi.org/10.1158/1538-7445.am2020-4443
Autor:
Satoshi Tanaka, Noriyasu Hirasawa, Kazuyuki Furuta, Yasushi Okuno, Mayuko Natsuhara, Kazuhisa Nakayama, Soken Tsuchiya, Hirotsugu Takano, Mariko Sakanaka, Yukihiko Sugimoto, Hiroshi Ohtsu, Shunsuke Nakazawa, Masahiro Nishibori, Robin L. Thurmond, Atsushi Ichikawa
Publikováno v:
European Journal of Immunology. 44:204-214
Mast cells are the major sources of histamine, which is released in response to immunological stimulations. The synthesis of histamine is catalyzed by histidine decarboxylase (HDC). Previous studies have shown that Hdc(-/-) mast cells exhibit aberran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76f82dbf2793ece97f5546163148859f
https://doi.org/10.1002/eji.201343838
https://doi.org/10.1002/eji.201343838
Autor:
Hirotsugu Takano, Masakazu Kobayashi, Takeaki Satoh, Masaaki Shimada, Makoto Nakamuta, Takashi Toyama, Hiroshi Yatsuhashi, Eiji Mita, Toshiki Komeda, Hajime Ohta, Hiromi Ishibashi, Yukio Watanabe, Michiyasu Yagura, Hisashi Ishida, Hiroshi Mano, Michio Kato, Taizo Hijioka
Publikováno v:
Hepatology Research. 42:1168-1174
Aim: Add-on adefovir dipivoxil (ADV) therapy has been a standard rescue treatment for patients with lamivudine (LAM)-resistant chronic hepatitis B, but the overall benefits of long-term add-on ADV therapy are still limited. The aim of this study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4020e8f6006f7c2752a0a038735110bf
https://doi.org/10.1111/j.1872-034x.2012.01038.x
https://doi.org/10.1111/j.1872-034x.2012.01038.x
Autor:
Naritoshi Shirata, Kazushi Morimoto, Eri Segi-Nishida, Hirotsugu Takano, Yukihiko Sugimoto, Tomoaki Inazumi
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 8, Pp 1500-1508 (2011)
The prostaglandin (PG) receptors EP4 and FP have the potential to exert negative effects on adipogenesis, but the exact contribution of endogenous PG-driven receptor signaling to this process is not fully understood. In this study, we employed an adi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2277c7eded5e9edbcce31bebca186a0
http://www.sciencedirect.com/science/article/pii/S002222752036925X
http://www.sciencedirect.com/science/article/pii/S002222752036925X
Autor:
Shunsuke, Nakazawa, Mariko, Sakanaka, Kazuyuki, Furuta, Mayuko, Natsuhara, Hirotsugu, Takano, Soken, Tsuchiya, Yasushi, Okuno, Hiroshi, Ohtsu, Masahiro, Nishibori, Robin L, Thurmond, Noriyasu, Hirasawa, Kazuhisa, Nakayama, Atsushi, Ichikawa, Yukihiko, Sugimoto, Satoshi, Tanaka
Publikováno v:
European journal of immunology. 44(1)
Mast cells are the major sources of histamine, which is released in response to immunological stimulations. The synthesis of histamine is catalyzed by histidine decarboxylase (HDC). Previous studies have shown that Hdc(-/-) mast cells exhibit aberran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24b44b10ca6e03fa795d8b41d7972264
https://pubmed.ncbi.nlm.nih.gov/24319003
https://pubmed.ncbi.nlm.nih.gov/24319003
Autor:
Takashi, Toyama, Hisashi, Ishida, Hiromi, Ishibashi, Hiroshi, Yatsuhashi, Makoto, Nakamuta, Masaaki, Shimada, Hajime, Ohta, Takeaki, Satoh, Michio, Kato, Taizo, Hijioka, Hirotsugu, Takano, Toshiki, Komeda, Michiyasu, Yagura, Hiroshi, Mano, Yukio, Watanabe, Masakazu, Kobayashi, Eiji, Mita
Publikováno v:
Hepatology research : the official journal of the Japan Society of Hepatology. 42(12)
Add-on adefovir dipivoxil (ADV) therapy has been a standard rescue treatment for patients with lamivudine (LAM)-resistant chronic hepatitis B, but the overall benefits of long-term add-on ADV therapy are still limited. The aim of this study was to ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2883793aa40b5f8de49f95ea99d8ea0
https://pubmed.ncbi.nlm.nih.gov/22594879
https://pubmed.ncbi.nlm.nih.gov/22594879
Autor:
Kazuyuki Furuta, Atsushi Irie, Hirotsugu Takano, Yukihiko Sugimoto, Naritoshi Shirata, Sohken Tsuchiya, Satoshi Tanaka, Shigero Tamba, Naoki Itano, Koji Kimata, Shunsuke Nakazawa, Atsushi Ichikawa, Kazushi Morimoto, Kazuhisa Nakayama
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 89(4)
By using the recently established culture system that reproduces the terminal differentiation process of connective tissue-type mast cells, we found significant transcriptional induction of CD44. As CD44 is a primary receptor for hyaluronan (HA), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a4e71b366ffc64e913b8667a2412b1
https://pubmed.ncbi.nlm.nih.gov/19204665
https://pubmed.ncbi.nlm.nih.gov/19204665
Autor:
Yoshitaka Taketomi, Seigoh Takamatsu, Ichiro Kudo, Atsushi Ichikawa, Makoto Murakami, Takayuki Kainoh, Kazuyuki Furuta, Hirotsugu Takano, Naritoshi Shirata, Yukihiko Sugimoto, Kazuhisa Nakayama, Gozoh Tsujimoto, Yasunori Kozutsumi, Yuko Naito, Hiromu Takematsu, Sohken Tsuchiya, Satoshi Tanaka, Shunsuke Nakazawa, Yasushi Okuno
Publikováno v:
FEBS letters. 582(10)
To understand physiological roles of tissue mast cells, we established a culture system where bone marrow-derived immature mast cells differentiate into the connective tissue-type mast cell (CTMC)-like cells through modifying the previous co-culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253f73d151161a109d12c634d56bb66d
https://pubmed.ncbi.nlm.nih.gov/18381075
https://pubmed.ncbi.nlm.nih.gov/18381075
Autor:
Yukihiko Sugimoto, Kazuyuki Furuta, Mariko Sakanaka, Satoshi Tanaka, Kazuhisa Nakayama, Atsushi Ichikawa, Eiichi Gohda, Kazuhito Yamashita, Hirotsugu Takano, Naoki Itano, Koji Kimata
Publikováno v:
ResearcherID
Appropriate culture models for tissue mast cells are required to determine how they are involved in regulation of local immune responses. We previously established a culture model for cutaneous mast cells, in which bone marrow-derived immature mast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f6ebb39258c4d1411d588c7dac18d3
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000300925200019&KeyUID=WOS:000300925200019
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000300925200019&KeyUID=WOS:000300925200019
