Výsledky vyhledávání - "Hirotsugu Ishizako"

New Class of Drug Modalities: Directed Evolution of a De Novo Designed Helix–Loop–Helix Peptide to Bind VEGF for Tumor Growth Inhibition

Autor: Masataka Michigami, Tharanga M. R. Ramanayake Mudiyanselage, Miho Suzuki, Hirotsugu Ishizako, Kunpei Notsu, Kikuya Sugiura, Ikuo Fujii

Publikováno v: ACS Chemical Biology. 17:647-653

As a small affinity molecule to serve as an alternative to antibodies, we have developed a conformationally constrained peptide with a de novo designed helix-loop-helix (HLH) scaffold. To evaluate its potential for biomedical applications, we perform

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a58d4bea81688f71fbb748df821344
https://doi.org/10.1021/acschembio.1c00940

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání