Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hirotoshi Unno"'
Autor:
Hideaki Morita, Ken Arae, Hirotoshi Unno, Sumika Toyama, Kenichiro Motomura, Akio Matsuda, Hajime Suto, Ko Okumura, Katsuko Sudo, Takao Takahashi, Hirohisa Saito, Kenji Matsumoto, Susumu Nakae
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134226 (2015)
IL-25, IL-33 and TSLP are produced predominantly by epithelial cells and are known to induce Th2-type cytokines. Th2-type cytokines are involved not only in host defense against nematodes, but also in the development of Th2-type allergic diseases. TS
Externí odkaz:
https://doaj.org/article/2a9b17100f2d485dab465686154d5b83
Autor:
Yu Okada, Noriyuki Yanagida, Sakura Sato, Ayako Ogawa, Kanako Ogura, Kenichi Nagakura, Shigehito Emura, Tomoyuki Asaumi, Hirotoshi Unno, Tetsuharu Manabe, Kiyotake Ogura, Katsuhito Iikura, Motohiro Ebisawa
Publikováno v:
Allergology International, Vol 64, Iss 2, Pp 192-193 (2015)
Externí odkaz:
https://doaj.org/article/640a9404c73f468c927e91891c33a523
Autor:
Hajime Suto, Hirohisa Saito, Katsuko Sudo, Akira Matsuda, Susumu Nakae, Ken Arae, Hirotoshi Unno, Akio Matsuda, Masashi Ikutani, Ko Okumura, Kenji Matsumoto, Kenichiro Motomura, Masato Tamari, Hideaki Morita, Sumika Toyama
Publikováno v:
Biochemical and Biophysical Research Communications. 533:493-500
Silica crystals (silica), which are a major mineral component of volcanic ash and desert dust, contribute to the pathogenesis of pulmonary disorders such as asthma and fibrosis. Although administration of silica or sand dust to rodents exacerbates de
Autor:
Keisuke Orimo, Masato Tamari, Ko Okumura, Yuko Mishima, Hirotoshi Unno, Kenji Matsumoto, Katsuko Sudo, Susumu Nakae, Hiroshi Miyazawa, Hirohisa Saito, Tatsukuni Ohno, Ken Arae, Kenichiro Motomura, Naoko Okada, Hajime Suto, Haruhiko Taguchi, Hideaki Morita, Sumika Toyama
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Chitin, which is a major component of house dust mites (HDM), fungi, crustaceans, etc., can activate immune cells, suggesting that it contributes to development of allergic disorders such as asthma. Although the pathophysiological sensitization route
Autor:
Michael J. Sanderson, David H. Broide, Peter Rosenthal, Hirotoshi Unno, Jun Chen, Marina Miller
Publikováno v:
The Journal of allergy and clinical immunology, vol 142, iss 1
Background Airway hyperresponsiveness is a major feature of asthma attributed predominantly to an extrinsic immune/inflammatory response increasing airway smooth muscle (ASM) contractility. Objective We investigated whether increased ASM expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e552a7f35c0da1b50a7ebf2988ce4e3
https://escholarship.org/uc/item/6mm8b8f7
https://escholarship.org/uc/item/6mm8b8f7
Autor:
Jun, Chen, Marina, Miller, Hirotoshi, Unno, Peter, Rosenthal, Michael J, Sanderson, David H, Broide
Publikováno v:
The Journal of allergy and clinical immunology. 142(1)
Airway hyperresponsiveness is a major feature of asthma attributed predominantly to an extrinsic immune/inflammatory response increasing airway smooth muscle (ASM) contractility.We investigated whether increased ASM expression of orosomucoid-like 3 (
Autor:
Ken Arae, Kenji Matsumoto, Hideaki Morita, Kyoko Futamura, Hirohisa Saito, Susumu Nakae, Hiroyuki Ida, Hirotoshi Unno, Reiji Kojima, Akio Matsuda
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 51:344-353
Silica crystals (silica), which are the main mineral component of volcanic ash and desert dust, can activate the caspase-1-activating inflammasome in phagocytic cells to secrete IL-1β. Although inhalation of silica-containing dust is known to exacer
Autor:
Kenji Matsumoto, Hideaki Morita, Hirohisa Saito, Hirotoshi Unno, Jun Abe, Koji Munechika, Yutaka Hirao, Akio Matsuda
Publikováno v:
European Journal of Immunology. 42:2121-2131
High-dose infusion of IgG (IVIG) is used to treat autoimmune and inflammatory diseases, including Kawasaki disease (KD). Although the immunomodulatory effects of IVIG on blood cells such as macrophages have been well studied, its effects on tissue ce
Publikováno v:
Journal of Allergy and Clinical Immunology. 141:439-442.e4
Autor:
Hirotoshi Unno, Ko Okumura, Susumu Nakae, Hideaki Morita, Sumika Toyama, Akio Matsuda, Kenichiro Motomura, Takao Takahashi, Katsuko Sudo, Kenji Matsumoto, Hirohisa Saito, Hajime Suto, Ken Arae
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134226 (2015)
PLoS ONE
PLoS ONE
Background IL-25, IL-33 and TSLP are produced predominantly by epithelial cells and are known to induce Th2-type cytokines. Th2-type cytokines are involved not only in host defense against nematodes, but also in the development of Th2-type allergic d