Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hirotomo Sasaki"'
Acceleration of autoimmune diabetes in Rheb-congenic NOD mice with β-cell-specific mTORC1 activation
Autor:
Mami Shimizu, Akira Nakamura, Hirotomo Sasaki, Masao Nagata, Kenta Hara, Hisafumi Yasuda, Hiroaki Moriyama, Koichi Yokono, Takashi Arai
Publikováno v:
Biochemical and Biophysical Research Communications. 408:306-311
The protein Ras homolog enriched in brain (Rheb) is a Ras-like small GTPase that activates the mechanistic target of rapamycin complex 1 (mTORC1), which promotes cell growth. We previously generated transgenic C57BL/6 mice overexpressing Rheb in β-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd20afb3d235b05bbf5a0b0319fa46e
https://doi.org/10.1016/j.bbrc.2011.04.026
https://doi.org/10.1016/j.bbrc.2011.04.026
Publikováno v:
SID Symposium Digest of Technical Papers. 38:1213-1215
We have developed a new type of transparent conductive mesh film based on silver halide photographic technologies. It has been applied to an electromagnetic interference shielding film for Plasma Display Panels, characterized by seamless mesh on a lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ab35694465e81bd5f7d426e4566192c
https://doi.org/10.1889/1.2785528
https://doi.org/10.1889/1.2785528
Publikováno v:
Synthetic Communications. 26:2503-2509
The conjugate addition of 1-alkenyl(disiamyl)boranes to α,β-unsaturated ketones, esters, or nitriles was carried out in the presence of Ni(acac)2 and triethylamine in DMF. The reactions provided γ,δ-unsaturated ketones, esters, and nitriles in hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2071db71ae43819bdd20e19d9356156
https://doi.org/10.1080/00397919608004563
https://doi.org/10.1080/00397919608004563
Publikováno v:
ChemInform. 23
A series of lithium tellurocarboxylates (1) were obtained as orange to red oils containing an equivalent of THF and LiCl from the reaction of acyl chlorides with lithium telluride. The salts (1) are extremely sensitive towards oxygen. Lithium benzene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2ec278d43a7168178d0b9636ec694b0
https://doi.org/10.1002/chin.199228230
https://doi.org/10.1002/chin.199228230
Publikováno v:
ChemInform. 27
The conjugate addition of 1-alkenyl(disiamyl)boranes to α,β-unsaturated ketones, esters, or nitriles was carried out in the presence of Ni(acac)2 and triethylamine in DMF. The reactions provided γ,δ-unsaturated ketones, esters, and nitriles in hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d2a58db83fe319ffa2e9b6b8de4743
https://doi.org/10.1002/chin.199639101
https://doi.org/10.1002/chin.199639101
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::009af9775f9afcff6e7c0b390c1459b7
https://doi.org/10.1002/chin.200210252
https://doi.org/10.1002/chin.200210252
Autor:
Takashi Arai, Hirotomo Sasaki, Koichi Yokono, Hiroaki Moriyama, Masao Nagata, Minoru Kishi, Yasuyo Okumachi, Hisafumi Yasuda, Kenta Hara, Yasuhisa Abe, Mami Shimizu
Publikováno v:
Biochemical and biophysical research communications. 394(1)
Antigen-specific regulatory CD4(+) T cells have been described but there are few reports on regulatory CD8(+) T cells. We generated islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP)-specific regulatory CD8(+) T cells from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c05130abb91148306da438e9289f40
https://pubmed.ncbi.nlm.nih.gov/20206130
https://pubmed.ncbi.nlm.nih.gov/20206130
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 67:27-32
A series of lithium tellurocarboxylates (1) were obtained as orange to red oils containing an equivalent of THF and LiCl from the reaction of acyl chlorides with lithium telluride. The salts (1) are extremely sensitive towards oxygen. Lithium benzene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::032d711b880c9495eaef2c3453000ed1
https://doi.org/10.1080/10426509208045815
https://doi.org/10.1080/10426509208045815
Autor:
Hiroaki Moriyama, Masao Nagata, Koichi Yokono, Hisafumi Yasuda, Takashi Arai, Minoru Kishi, Mami Shimizu, Hirotomo Sasaki, Yasuyo Okumachi, Kenta Hara
Publikováno v:
Clinical immunology (Orlando, Fla.). 136(1)
Antigen-specific immunotherapy is expected to be an ideal strategy for treating type 1 diabetes (T1D). We investigated the therapeutic efficacy of a peptide in the leader sequence of preproinsulin, which was selected because of its binding affinity t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640c236b8460ab1367bd699420714408
https://pubmed.ncbi.nlm.nih.gov/20359955
https://pubmed.ncbi.nlm.nih.gov/20359955
Publikováno v:
Journal of the American Chemical Society. 111:314-321
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d97d2bd7f24feeafb395c433ef023891
https://doi.org/10.1021/ja00183a048
https://doi.org/10.1021/ja00183a048