Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hiroto Taki"'
Publikováno v:
Advances in Therapy. 22:621-635
Nateglinide is an oral antidiabetic medication (OAD) that acts through rapid, short-term stimulation of insulin production. This study was conducted to identify the nature of any adverse effects associated with nateglinide and to evaluate its clinica
Publikováno v:
Advances in Therapy. 22:513-526
Nateglinide is an oral antidiabetic medication that acts through rapid, short-term stimulation of insulin production. This study was undertaken to identify the incidence and nature of adverse effects of nateglinide and to assess its efficacy in clini
Publikováno v:
Cellular Immunology. 150:333-342
Cytotoxic properties of human activated macrophages were investigated by measuring both 51 Cr and [ 3 H]TdR releases from prelabeled target cells. The kinetic study of macrophage-mediated cytotoxicity indicated that 51 Cr and [ 3 H]TdR releases showe
Autor:
Hiroto Takiguchi, Chen X. Yang, Cheng Wei Tony Yang, Basak Sahin, Beth A. Whalen, Stephen Milne, Kentaro Akata, Kei Yamasaki, Julia Shun Wei Yang, Chung Yan Cheung, Ryan Vander Werff, Kelly M. McNagny, Fernando Sergio Leitao Filho, Tawimas Shaipanich, Stephan F. van Eeden, Ma’en Obeidat, Janice M. Leung, Don D. Sin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The classical M1/M2 polarity of macrophages may not be applicable to inflammatory lung diseases including chronic obstructive pulmonary disease (COPD) due to the complex microenvironment in lungs and the plasticity of macrophages. We examine
Externí odkaz:
https://doaj.org/article/052ad98032564138a6298f7a605c7d0d
Publikováno v:
Advances in therapy. 23(2)
Nateglinide is an oral antidiabetic medication that acts through rapid, short-term stimulation of insulin production. This study undertook to identify the nature of any adverse effects of nateglinide and to assess its clinical efficacy in long-term u
Autor:
Hiroto Takinami, Nobuo Ishiyama, Hino Takafumi, Takahiro Kubo, Kanji Tomita, Muku Tsujino, Futoshi Nakamura
Publikováno v:
Conservation Science and Practice, Vol 3, Iss 9, Pp n/a-n/a (2021)
Abstract Large carnivores encounter various threats from human activities. Population trend detection among carnivore species and implementation of management policies based on monitoring are urgently needed for human–carnivore coexistence. We demo
Externí odkaz:
https://doaj.org/article/c6323bf93f9d4f1d92bc89d2a321792d
Autor:
Takuya Aoki, Takeshi Akiba, Jun Nishiyama, Sakurako Tajiri, Naoki Hayama, Genki Takahashi, Jun Tanaka, Masako Sato, Hiroto Takiguchi, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Takahisa Takihara, Kyoko Niimi, Tsuyoshi Oguma, Mitsutomo Kohno, Ryota Masuda, Tetsuya Urano, Hitoshi Itoh, Hiroshi Kajiwara, Naoya Nakamura, Etsuo Kunieda, Mitsunori Matsumae, Masayuki Iwazaki, Koichiro Asano
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background Although development of immune checkpoint inhibitors and various molecular target agents has extended overall survival time (OS) in advanced non-small cell lung cancer (NSCLC), a complete cure remains rare. We aimed to identify fe
Externí odkaz:
https://doaj.org/article/aceb80a7728c4724bab97a6e4d239c59
Autor:
Hiroto Takiguchi, Virginia Chen, Ma’en Obeidat, Zsuzsanna Hollander, J. Mark FitzGerald, Bruce M. McManus, Raymond T. Ng, Don D. Sin
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Effects of systemic corticosteroids on blood gene expression are largely unknown. This study determined gene expression signature associated with short-term oral prednisone therapy in patients with chronic obstructive pulmonary di
Externí odkaz:
https://doaj.org/article/6432bca4422c4374a082f405aa1cb3b6
Autor:
Kentaro Akata, Kei Yamasaki, Fernando Sergio Leitao Filho, Chen Xi Yang, Hiroto Takiguchi, Basak Sahin, Beth A. Whalen, Cheng Wei Tony Yang, Janice M. Leung, Don D. Sin, Stephan F. van Eeden
Publikováno v:
Biomedicines, Vol 8, Iss 10, p 398 (2020)
Lung macrophages are the key immune effector cells in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Several studies have shown an increase in their numbers in bronchoalveolar lavage fluid (BAL) of subjects with COPD compared to co
Externí odkaz:
https://doaj.org/article/0535300b8f744d43a4afde119a7d7c2d
Autor:
Hiroto Takiguchi, Tomoe Takeuchi, Kyoko Niimi, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Naoki Hayama, Tsuyoshi Oguma, Takuya Aoki, Tetsuya Urano, Satomi Asai, Hayato Miyachi, Koichiro Asano
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196132 (2018)
Chronic obstructive pulmonary disease (COPD) mainly develops after long-term exposure to cigarette or biomass fuel smoke, but also occurs in non-smokers with or without a history of asthma. We investigated the proportion and clinical characteristics
Externí odkaz:
https://doaj.org/article/77fe0bf8c9cd4a669ab4028434f5dcfd