Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Hiroto TAKIGUCHI"'
Autor:
Hiroto Takiguchi, Chen X. Yang, Cheng Wei Tony Yang, Basak Sahin, Beth A. Whalen, Stephen Milne, Kentaro Akata, Kei Yamasaki, Julia Shun Wei Yang, Chung Yan Cheung, Ryan Vander Werff, Kelly M. McNagny, Fernando Sergio Leitao Filho, Tawimas Shaipanich, Stephan F. van Eeden, Ma’en Obeidat, Janice M. Leung, Don D. Sin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The classical M1/M2 polarity of macrophages may not be applicable to inflammatory lung diseases including chronic obstructive pulmonary disease (COPD) due to the complex microenvironment in lungs and the plasticity of macrophages. We examine
Externí odkaz:
https://doaj.org/article/052ad98032564138a6298f7a605c7d0d
Autor:
Takuya Aoki, Takeshi Akiba, Jun Nishiyama, Sakurako Tajiri, Naoki Hayama, Genki Takahashi, Jun Tanaka, Masako Sato, Hiroto Takiguchi, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Takahisa Takihara, Kyoko Niimi, Tsuyoshi Oguma, Mitsutomo Kohno, Ryota Masuda, Tetsuya Urano, Hitoshi Itoh, Hiroshi Kajiwara, Naoya Nakamura, Etsuo Kunieda, Mitsunori Matsumae, Masayuki Iwazaki, Koichiro Asano
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background Although development of immune checkpoint inhibitors and various molecular target agents has extended overall survival time (OS) in advanced non-small cell lung cancer (NSCLC), a complete cure remains rare. We aimed to identify fe
Externí odkaz:
https://doaj.org/article/aceb80a7728c4724bab97a6e4d239c59
Autor:
Hiroto Takiguchi, Virginia Chen, Ma’en Obeidat, Zsuzsanna Hollander, J. Mark FitzGerald, Bruce M. McManus, Raymond T. Ng, Don D. Sin
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Effects of systemic corticosteroids on blood gene expression are largely unknown. This study determined gene expression signature associated with short-term oral prednisone therapy in patients with chronic obstructive pulmonary di
Externí odkaz:
https://doaj.org/article/6432bca4422c4374a082f405aa1cb3b6
Autor:
Kentaro Akata, Kei Yamasaki, Fernando Sergio Leitao Filho, Chen Xi Yang, Hiroto Takiguchi, Basak Sahin, Beth A. Whalen, Cheng Wei Tony Yang, Janice M. Leung, Don D. Sin, Stephan F. van Eeden
Publikováno v:
Biomedicines, Vol 8, Iss 10, p 398 (2020)
Lung macrophages are the key immune effector cells in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Several studies have shown an increase in their numbers in bronchoalveolar lavage fluid (BAL) of subjects with COPD compared to co
Externí odkaz:
https://doaj.org/article/0535300b8f744d43a4afde119a7d7c2d
Autor:
Hiroto Takiguchi, Tomoe Takeuchi, Kyoko Niimi, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Naoki Hayama, Tsuyoshi Oguma, Takuya Aoki, Tetsuya Urano, Satomi Asai, Hayato Miyachi, Koichiro Asano
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196132 (2018)
Chronic obstructive pulmonary disease (COPD) mainly develops after long-term exposure to cigarette or biomass fuel smoke, but also occurs in non-smokers with or without a history of asthma. We investigated the proportion and clinical characteristics
Externí odkaz:
https://doaj.org/article/77fe0bf8c9cd4a669ab4028434f5dcfd
Autor:
Tsuyoshi Oguma, Takashi Nagaoka, Muneshige Kurahashi, Naofumi Kobayashi, Shinji Yamamori, Chizuko Tsuji, Hiroto Takiguchi, Kyoko Niimi, Hiromi Tomomatsu, Katsuyoshi Tomomatsu, Naoki Hayama, Takuya Aoki, Tetsuya Urano, Kazushige Magatani, Sunao Takeda, Tadashi Abe, Koichiro Asano
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174802 (2017)
BACKGROUND:Exhaled volatile organic compounds (VOC) are being considered as biomarkers for various lungs diseases, including cancer. However, the accurate measurement of extremely low concentrations of VOC in expired air is technically challenging. W
Externí odkaz:
https://doaj.org/article/bfc5cf801b944551a420a6d10cffe895
Autor:
Naokata KUTSUZAWA, Hiroto TAKIGUCHI, Haruka IKOMA, Nobue KUMAKI, Tomoo NAGAI, Mitsuharu UEDA, Yoshitaka ONO, Yukihiro HORIO, Kyoko NIIMI, Naoki HAYAMA, Yoko ITO, Tsuyoshi OGUMA, Koichiro ASANO
Publikováno v:
Tokai Journal of Experimental & Clinical Medicine; Sep2023, Vol. 48 Issue 3, p91-94, 4p
Autor:
Stephen Lam, Cheng Wei Tony Yang, Janice M. Leung, Fernando Sergio Leitao Filho, Seung Won Ra, Corey Nislow, Stephen Milne, Kentaro Akata, Yuji Cho, Julia Yang, Ji-Yong Moon, Tawimas Shaipanich, Hiroto Takiguchi, Hyun Kuk Kim, Don D. Sin, Xuan Li, Kei Yamasaki, Stephan F. van Eeden
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 204:1143-1152
Rationale: Inhaled corticosteroids (ICS) are commonly prescribed with long-acting β2-agonists (LABA) in chronic obstructive pulmonary disease (COPD). To date, the effects of ICS therapy on the airw...
Autor:
Naoki OKADA, Kyoko NIIMI, Yoshino ASAMI, Shigeaki HATTORI, Hiroto TAKIGUCHI, Naoki HAYAM, Yoko ITO, Tsuyoshi OGUMA, Shun ONO, Koichiro ASANO
Publikováno v:
Tokai Journal of Experimental & Clinical Medicine; Apr2023, Vol. 48 Issue 1, p47-51, 5p
Autor:
Masashi Miyaoka, Genki Takahashi, Tsuyoshi Oguma, Koichiro Asano, Shigeaki Hattori, Kyoko Niimi, Kana Ohshinden, Takahisa Takihara, Jun Tanaka, Hiroto Takiguchi, Keito Enokida, Yoko Ito, Naoki Hayama, Fuminari Takahashi, Mari Takahashi, Kenichi Hirabayashi, Yukihiro Horio
Publikováno v:
Internal Medicine
A 72-year-old man was treated with prednisolone and cyclosporine A for idiopathic pulmonary fibrosis. A nodule with a diameter of 19 mm was found in the right lung and diagnosed as lung squamous cell carcinoma. Anti-cancer treatments were not perform