Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hiroto Iwai"'
Autor:
Keiji Uehara, Toshimasa Harumoto, Asana Makino, Yasuo Koda, Junko Iwano, Yasuhiro Suzuki, Mari Tanigawa, Hiroto Iwai, Kana Asano, Kana Kurihara, Akinori Hamaguchi, Hiroshi Kodaira, Toshiyuki Atsumi, Yoji Yamada, Kazuma Tomizuka
Publikováno v:
Nucleic Acids Research. 50:4840-4859
Extrahepatic delivery of small interfering RNAs (siRNAs) may have applications in the development of novel therapeutic approaches. However, reports on such approaches are limited, and the scarcity of reports concerning the systemically targeted deliv
Autor:
Toshimasa Harumoto, Hiroto Iwai, Mari Tanigawa, Toshiko Kubo, Toshiyuki Atsumi, Kyoko Tsutsumi, Michio Takashima, Giuseppe Destito, Rachel Soloff, Kazuma Tomizuka, Corwin Nycholat, James Paulson, Keiji Uehara
Publikováno v:
ACS Chemical Biology. 17:292-298
Extrahepatic targeted delivery of oligonucleotides, such as small interfering RNA (siRNA) and antisense oligonucleotides (ASOs), is an attractive technology for the development of nucleic acid-based medicines. To target CD22-expressing B cells, sever
Creation of a Ligand-Dependent Enzyme by Fusing Circularly Permuted Antibody Variable Region Domains
Publikováno v:
Bioconjugate Chemistry. 27:868-873
Allosteric control of enzyme activity with exogenous substances has been hard to achieve, especially using antibody domains that potentially allow control by any antigens of choice. Here, in order to attain this goal, we developed a novel antibody va
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1596
Antibody-based molecular switches that are able to recognize a range of exogenous antigens can be highly useful as a versatile biosensor. However, regulating the catalytic activity of enzymes by antibodies is still hard to achieve. Here, we describe
Publikováno v:
Methods in Molecular Biology ISBN: 9781493969388
Antibody-based molecular switches that are able to recognize a range of exogenous antigens can be highly useful as a versatile biosensor. However, regulating the catalytic activity of enzymes by antibodies is still hard to achieve. Here, we describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::455180d2fa1740a406374cc27735e796
https://doi.org/10.1007/978-1-4939-6940-1_10
https://doi.org/10.1007/978-1-4939-6940-1_10
Publikováno v:
Protein Engineering, Design and Selection, 23(4), 185-193
Protein Engineering, Design and Selection 23 (2010) 4
Protein Engineering, Design and Selection 23 (2010) 4
Selection of antibody library in vitro is almost always performed on a certain solid-phase with immobilized antigen. However, for the selection of small molecule binders, conjugation of the antigen to a carrier molecule is indispensable, which often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355edfcc4de419dfcadff56b3e42e03b
https://research.wur.nl/en/publications/antibody-affinity-maturation-in-vitro-using-unconjugated-peptide-
https://research.wur.nl/en/publications/antibody-affinity-maturation-in-vitro-using-unconjugated-peptide-
Publikováno v:
Journal of Proteomics & Bioinformatics. :316-317
Autor:
Miki Kojima, Hiroto Iwai, Jinhua Dong, Shean-Lee Lim, Shigekazu Ito, Koichi Okumura, Masaki Ihara, Hiroshi Ueda
Publikováno v:
Bioconjugate Chemistry; Apr2011, Vol. 22 Issue 4, p633-641, 9p