Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hiroto Inagaki"'
Publikováno v:
Biochemical and Biophysical Research Communications. 553:9-16
The RNA-binding protein Ataxin-2 regulates translation and mRNA stability through cytoplasmic polyadenylation of the targets. Here we newly identified DDX6 as a positive regulator of the cytoplasmic polyadenylation. Analysis of Ataxin-2 interactome u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb45e3408e117d237f1b42a1cbf0fe32
https://doi.org/10.1016/j.bbrc.2021.03.066
https://doi.org/10.1016/j.bbrc.2021.03.066
Autor:
Koichi Ogami, Yuka Oishi, Kentaro Sakamoto, Mayu Okumura, Ryota Yamagishi, Takumi Inoue, Masaya Hibino, Takuto Nogimori, Natsumi Yamaguchi, Kazuya Furutachi, Nao Hosoda, Hiroto Inagaki, Shin-ichi Hoshino
Publikováno v:
Cell Reports. 41:111548
Translation of 5' terminal oligopyrimidine (TOP) mRNAs encoding the protein synthesis machinery is strictly regulated by an amino-acid-sensing mTOR pathway. However, its regulatory mechanism remains elusive. Here, we demonstrate that TOP mRNA transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb1b387054335f178ae1347e5e0d9c4
https://doi.org/10.1016/j.celrep.2022.111548
https://doi.org/10.1016/j.celrep.2022.111548
Publikováno v:
J Biol Chem
The RNA-binding protein Ataxin-2 binds to and stabilizes a number of mRNA sequences, including that of the transactive response DNA-binding protein of 43 kDa (TDP-43). Ataxin-2 is additionally involved in several processes requiring translation, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a759d5522723021ff963dea83753bd0
https://pubmed.ncbi.nlm.nih.gov/32989052
https://pubmed.ncbi.nlm.nih.gov/32989052
Autor:
Hiroto Inagaki1, Nao Hosoda1, Hitomi Tsuiji2, Shin-ichi Hoshino1 hoshino@phar.nagoya-cu.ac.jp
Publikováno v:
Journal of Biological Chemistry. 11/20/2020, Vol. 295 Issue 47, p15810-15825. 22p.
Publikováno v:
FEBS Letters. (17):2241-2247
The involvement of polypeptide chain-releasing factor eRF3 in translation termination and mRNA decay is well established. Moreover, the finding that the proteolytically processed isoform of eRF3 (p-eRF3) interacts with inhibitors of apoptosis protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbfbb914d5a9458939f42bc9e197ff85