Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Hiroto, Kuwabara"'
Autor:
Gwenn S. Smith, Hillary Protas, Hiroto Kuwabara, Alena Savonenko, Najlla Nassery, Neda F. Gould, Michael Kraut, Dimitri Avramopoulos, Daniel Holt, Robert F. Dannals, Ayon Nandi, Yi Su, Eric M. Reiman, Kewei Chen
Publikováno v:
NeuroImage: Clinical, Vol 37, Iss , Pp 103322- (2023)
Background: Degeneration of the serotonin system has been observed in Alzheimer’s disease (AD) and in mild cognitive impairment (MCI). In transgenic amyloid mouse models, serotonin degeneration is detected prior to widespread cortical beta-amyloid
Externí odkaz:
https://doaj.org/article/9f77b3ae48cb4778880522ffadcdb828
Autor:
Gwenn S. Smith, Clifford I. Workman, Hillary Protas, Yi Su, Alena Savonenko, Hiroto Kuwabara, Neda F. Gould, Michael Kraut, Jin Hui Joo, Ayon Nandi, Dimitri Avramopoulos, Eric M. Reiman, Kewei Chen
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Depression in late-life is associated with increased risk of cognitive decline and development of all-cause dementia. The neurobiology of late-life depression (LLD) may involve both neurochemical and neurodegenerative mechanisms that are com
Externí odkaz:
https://doaj.org/article/01ad391dea8843638cdd171ec1cb677d
Autor:
Brian A. Anderson, Hiroto Kuwabara, Dean F. Wong, Joshua Roberts, Arman Rahmim, James R. Brašić, Susan M. Courtney
Publikováno v:
NeuroImage, Vol 157, Iss , Pp 27-33 (2017)
The attention system is shaped by reward history, such that learned reward cues involuntarily draw attention. Recent research has begun to uncover the neural mechanisms by which learned reward cues compete for attention, implicating dopamine (DA) sig
Externí odkaz:
https://doaj.org/article/667ed28315a64bbea7c8519785938b8d
Autor:
Michael Honer, Alessandra Polara, Hiroto Kuwabara, Helmut Jacobsen, Axel Pähler, Thomas Hartung, Antonello Caruso, Daria Esterhazy, Markus Stoffel, Robert F. Dannals, Dean F. Wong, Edilio Borroni, Luca C. Gobbi
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc1e7a5a455c4e77c70b6a67ad02ae82
https://doi.org/10.1002/jlcr.4025
https://doi.org/10.1002/jlcr.4025
Autor:
Hillary Protas, Dimitri Avramopoulos, Kewei Chen, Eric M. Reiman, Gwenn S. Smith, Jin Hui Joo, Alena Savonenko, Yi Su, Neda F Gould, Ayon Nandi, Hiroto Kuwabara, Clifford I. Workman, Michael A. Kraut
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Depression in late-life is associated with increased risk of cognitive decline and development of all-cause dementia. The neurobiology of late-life depression (LLD) may involve both neurochemical and neurodegenerative mechanisms that are common to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ac24142bc7e3edd2529ad5388e90fd
https://doaj.org/article/01ad391dea8843638cdd171ec1cb677d
https://doaj.org/article/01ad391dea8843638cdd171ec1cb677d
Autor:
Janelle E. Letzen, Carly Hunt, Hiroto Kuwabara, Lakeya S. McGill, Matthew J. Reid, Katrina R. Hamilton, Luis F. Buenaver, Emily Burton, Rosanne Sheinberg, Dean F. Wong, Michael T. Smith, Claudia M. Campbell
Publikováno v:
The journal of pain. 24(1)
Sleep disturbance predicts worse pain outcomes. Because sleep disturbance inequitably impacts Black adults - with racism as the upstream cause - understanding how racism-related stress impacts pain through sleep might help minimize racialized pain in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9127ed371eed476f9bc01bcb68f05222
https://pubmed.ncbi.nlm.nih.gov/36167231
https://pubmed.ncbi.nlm.nih.gov/36167231
Autor:
Arash Raoufinia, Dean F. Wong, James Robert Brašić, Robert A. Forbes, Robert D. McQuade, Hiroto Kuwabara, Tetsuro Kikuchi, Patricia Bricmont
Publikováno v:
European Journal of Clinical Pharmacology
Purpose The aim of this Phase 1, open-label, positron emission tomography (PET) study was to determine the degree of striatal D2/D3 receptor occupancy induced by the serotonin–dopamine activity modulator, brexpiprazole, at different single dose lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2254233a6c7b7145d374f5e6f108883
https://doi.org/10.1007/s00228-020-03021-9
https://doi.org/10.1007/s00228-020-03021-9
Autor:
Hiroto Kuwabara, Albert Gjedde
Publikováno v:
Radiopharmaceuticals and Brain Pathology Studied with PET and SPECT ISBN: 9780429278983
This chapter examines the interaction between tracer glucose uptake and phosphor-ylation in brain. It derives the equations for the use of labeled deoxyglucose, fluorodeoxyglucose, or glucose itself to calculate brain glucose phosphorylation. The cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2374400aad3f429021b5e305d710896b
https://doi.org/10.4324/9780429278983-8
https://doi.org/10.4324/9780429278983-8
Autor:
Daniel A. Stevens, Clifford I. Workman, Hiroto Kuwabara, Meryl A. Butters, Alena Savonenko, Najilla Nassery, Neda Gould, Michael Kraut, Jin Hui Joo, Jessica Kilgore, Vidya Kamath, Daniel P. Holt, Robert F. Dannals, Ayon Nandi, Chiadi U. Onyike, Gwenn S. Smith
Publikováno v:
Brain communications. 4(1)
Beta-amyloid deposition is one of the earliest pathological markers associated with Alzheimer's disease. Mild cognitive impairment in the setting of beta-amyloid deposition is considered to represent a preclinical manifestation of Alzheimer's disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8522c3f2c1e0077bf8c96f3899a70676
https://pubmed.ncbi.nlm.nih.gov/35233522
https://pubmed.ncbi.nlm.nih.gov/35233522
Publikováno v:
Nicotine Tob Res
Introduction Cigarette smoking continues to be one of the most important behavioral causes of morbidity and mortality in the world. Varenicline, an α4β2 nicotinic acetylcholine receptor (nAChR) partial agonist, has been shown to increase smoking qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeecf0dff962585ef86d2d0465bc2c8
https://doi.org/10.1093/ntr/ntz080
https://doi.org/10.1093/ntr/ntz080