Výsledky vyhledávání - "Hirotaka Ogata"

MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4

Autor: Kenji Fukudome, Kensuke Miyake, Masao Kimoto, Hirotaka Ogata, Yoshinori Nagai, Rintaro Shimazu, Sachiko Akashi

Publikováno v: The Journal of Experimental Medicine

Toll-like receptor 4 (TLR4) is a mammalian homologue of Drosophila Toll, a leucine-rich repeat molecule that can trigger innate responses against pathogens. The TLR4 gene has recently been shown to be mutated in C3H/HeJ and C57BL/10ScCr mice, both of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbc3c33a892da1489ce323f2bfce197
https://doi.org/10.1084/jem.189.11.1777

Zobrazit plný text záznamu

Performance and Regeneration of Lead-acid Batteries and the Use of Battery Activator for Electric Wheel Chairs

Autor: Kazuhiro Tachibana, Tatsuo Nishina, Hirotaka Ogata, Kunio Watanabe, Kenichi Nakagawa, Akiya Kozawa, Michio Sugawara

Publikováno v: Journal of Asian Electric Vehicles. 5:971-973

The driving and charge-discharge tests were carried out on the used lead-acid batteries for electric wheel chair. When the used batteries were repeatedly subjected to driving test on road after full charge, the electricity delivered from the battery

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d491a2958c99a98801ff36fd279b213
https://doi.org/10.4130/jaev.5.971

Zobrazit plný text záznamu

RP105 Is Associated With MD-1 and Transmits an Activation Signal in Human B Cells

Autor: Kensuke Miyake, Yoshihiro Miura, Rintaro Shimazu, Yoshio Yamashita, Yutaka Narisawa, Hirotaka Ogata, Sachiko Akashi, Masao Kimoto

Publikováno v: Blood. 92:2815-2822

RP105 was originally discovered as a mouse B-cell surface molecule that transmits an activation signal. The signal leads to resistance against irradiation-induced apoptosis and massive B-cell proliferation. Recently, we found that mouse RP105 is asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5ab57c77e0f7356ee8e81ca114ee7f
https://doi.org/10.1182/blood.v92.8.2815

Zobrazit plný text záznamu

Marked over expression of uncoupling protein-2 in beta cells exerts minor effects on mitochondrial metabolism

Autor: Kjartan Egeberg, Elin Pettersen, Hirotaka Ogata, Valdemar Grill, Ingrid Hals, Zuheng Ma, Frank Skorpen, Anneli Björklund

Publikováno v: Biochemical and biophysical research communications. 423(2)

Highlights: Black-Right-Pointing-Pointer The impact of UCP-2 over expression on mitochondrial function is controversial. Black-Right-Pointing-Pointer We tested mitochondrial functions at defined levels of overexpression. Black-Right-Pointing-Pointer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f10412ffb0d626c00abd9eae18a556a
https://pubmed.ncbi.nlm.nih.gov/22634308

Zobrazit plný text záznamu

Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation

Autor: Claes B. Wollheim, Hirotaka Ogata, Zuheng Ma, Anneli Björklund, Ingrid Hals Jørgensen, Tina Wallin, Mariella Iezzi, Haiyan Wang

Publikováno v: Biochimica et Biophysica Acta, Vol. 1801, No 2 (2010) pp. 191-7

Facilitation of fatty acid uptake in beta cells could potentially affect beta cell metabolism and secretory function; however such effects have not been clearly documented. CD36 facilitates uptake of fatty acids (FA) in muscle and adipose tissue and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a941e85f32c38087121562916f212cf8
https://archive-ouverte.unige.ch/unige:33548

Zobrazit plný text záznamu

Requirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharide

Autor: Hirotaka Ogata, Yoichiro Iwakura, Sachiko Akashi, Hidetoshi Yamasaki, Yoshinori Nagai, Kensuke Miyake, Katsuko Sudo, Rintaro Shimazu, Shin-Ichi Hayashi, Masao Kimoto

Publikováno v: Blood. 99(5)

RP105 is a B-cell surface molecule that has been recently assigned as CD180. RP105 ligation with an antibody induces B-cell activation in humans and mice, leading to proliferation and up-regulation of a costimulatory molecule, B7.2/CD86. RP105 is ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e679595336aa849a7ef76a0073ed83
https://pubmed.ncbi.nlm.nih.gov/11861286

Zobrazit plný text záznamu

Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition

Autor: Sachiko Akashi, Masato Oikawa, Hirotaka Ogata, Koichi Fukase, Shoichi Kusumoto, Masahiro Nishijima, Kiyoshi Kawasaki, Shinichiro Hayashi, Masao Kimoto, Kensuke Miyake, Yoshinori Nagai

Publikováno v: International immunology. 13(12)

Toll-like receptor 4 (TLR4) recognizes lipopolysaccharide (LPS). MD-2 is associated with TLR4 and imparts LPS responsiveness to it. Little is known, however, as to whether MD-2 directly regulates LPS recognition by TLR4. To address the issue, we took

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afce21924a0e9edd1886b48dffa73ec1
https://pubmed.ncbi.nlm.nih.gov/11717200

Zobrazit plný text záznamu

Innate recognition of lipopolysaccharide by Toll-like receptor 4/MD-2 and RP105/MD-1

Autor: Sachiko Akashi, Yoshinori Nagai, Kensuke Miyake, Masao Kimoto, Hirotaka Ogata

Publikováno v: Journal of endotoxin research. 6(5)

The Toll family of receptors has been implicated in innate recognition and subsequent activation of defense programs against pathogens such as bacteria and fungi. TLR4, for example, signals the presence of lipopolysaccharide (LPS), a membrane constit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1398e61f70ef03b384a7c8fc0207a18
https://pubmed.ncbi.nlm.nih.gov/11521060

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání