Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hirotaka Kawakami"'
Publikováno v:
Viruses, Vol 13, Iss 12, p 2502 (2021)
Gene therapy is currently in the public spotlight. Several gene therapy products, including oncolytic virus (OV), which predominantly replicates in and kills cancer cells, and COVID-19 vaccines have recently been commercialized. Recombinant adenoviru
Externí odkaz:
https://doaj.org/article/6340549d304945fb954e9d0b40b37f14
Autor:
Yuki Katsukura, Yasuo Uchida, Junichi Kamiie, Kenji Nakamura, Tetsuya Terasaki, Chise Tateno, Wataru Obuchi, Hirotaka Kawakami, Tae Inoue, Sumio Ohtsuki, Toru Horie
Publikováno v:
Drug Metabolism and Disposition. 42:1039-1043
Chimeric mice with humanized liver (PXB mice) have been generated by transplantation of urokinase-type plasminogen activator/severe combined immunodeficiency mice with human hepatocytes. The purpose of the present study was to clarify the protein exp
Autor:
Ryosuke Kobayashi, Kyohei Yasuno, Saori Araki, Hirotaka Kawakami, Kikumi Ogihara, Kinji Shirota, Junichi Kamiie, Haruka Sakashita, Tomoshige Baba
Publikováno v:
Journal of Comparative Pathology. 149:280-290
Osborne-Mendel (OM) rats spontaneously develop glomerulopathy with progressive podocyte injury. Changes in protein expression levels in the foot processes of podocytes have been suggested to play an important role in the development of renal disease.
Autor:
Takako Yoshioka, Masahiro Yokouchi, Hideki Kawamura, Setsuro Komiya, Akihide Tanimoto, Satoshi Nagano, Takao Setoguchi, Hirotaka Kawakami, Hironori Kakoi, Junichiro Nishi, Yasuhiro Ishidou
Publikováno v:
BMC Musculoskeletal Disorders
Background Although most patients achieve favorable results following bipolar hip hemiarthroplasty (BHA), some experience rapid migration of the prosthesis. We retrospectively reviewed 18 patients with BHA that necessitated revision. Methods We exami
Autor:
Shinji Kamakura, Osamu Suzuki, Hidetoshi Shimauchi, Takahisa Anada, Hirofumi Kaneko, Junichi Kamiie, Yoshitomo Honda, Tetsuya Terasaki, Hirotaka Kawakami, Naru Shiraishi
Publikováno v:
Analytical Biochemistry. 418:276-285
The present study was designed to determine which proteins are selectively adsorbed onto two bone substitute materials, octacalcium phosphate (OCP) and hydroxyapatite (HA) crystals, from rat serum by proteome analysis. Ground crystals of synthetic OC
Autor:
Olaf Schaefer, Hirotaka Kawakami, Tetsuya Terasaki, Atsushi Sakamoto, Takehisa Matsumaru, Naoki Ishiguro, Tae Inoue, Sumio Ohtsuki
Publikováno v:
Journal of Pharmaceutical Sciences. 100:4037-4043
Mass spectrometry (MS)-based multiplexed multiple reaction monitoring quantification of proteins has recently evolved as a versatile tool for accurate, absolute quantification of proteins. The purpose of this study was to examine the validity of the
Autor:
Ryosuke Kobayashi, Kyohei Yasuno, Kinji Shirota, Hirotaka Kawakami, Junichi Kamiie, Naoyuki Aihara
Publikováno v:
Nephrology Dialysis Transplantation. 27:1324-1330
Background. The slit diaphragm (SD) is a complex of podocyte-specific proteins and plays a significant role in glomerular filtration. To understand podocyte biology, it is important to determine the expression amount of the SD complex proteins. This
Autor:
Takaaki Abe, Hirotaka Kawakami, Tetsuya Terasaki, Takashi Suzuki, Sumio Ohtsuki, Junichi Kamiie
Publikováno v:
Journal of Pharmaceutical Sciences. 100:341-352
Cytochrome P450 (CYP) proteins are involved in the biological oxidation and reduction of xenobiotics, affecting the pharmacological efficiency of drugs. This study aimed to establish a method to simultaneously quantify 11 CYP isoforms by multiplexed-
Autor:
Heyo K. Kroemer, Tetsuya Terasaki, Junichi Kamiie, Juliane Niessen, Gabriele Jedlitschky, Stefan Oswald, Dieter Rosskopf, Hirotaka Kawakami, Sumio Ohtsuki, Katharina Starke, Werner Siegmund, Ulrike Strobel, Markus Grube, Hansjörg Schwertz, Andreas Greinacher, Sandra Bien
Publikováno v:
Drug Metabolism and Disposition. 37:1129-1137
Statins are widely used to treat dyslipidemia. Effects of statins in addition to low-density lipoprotein lowering include altered platelet aggregation, requiring drug uptake into platelets. Possible candidates for mediating intraplatelet accumulation
Autor:
Yasuhiro Tsuneyoshi, Hirotaka Kawakami, Nobuhiko Sunahara, Tomoka Sanno, Tsuyoshi Takenouchi, Setsuro Komiya
Publikováno v:
Orthopedics & Traumatology. 58:491-495