Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hirotaka Amano"'
Publikováno v:
Molecules, Vol 22, Iss 4, p 570 (2017)
S-1-Propenyl-ʟ-cysteine (S1PC) is a stereoisomer of S-1-Propenyl-ʟ-cysteine (SAC), an important sulfur-containing amino acid that plays a role for the beneficial pharmacological effects of aged garlic extract (AGE). The existence of S1PC in garlic
Externí odkaz:
https://doaj.org/article/22e6646ec1d044899e1cac9b1c14e236
Publikováno v:
European Food Research and Technology. 246:1041-1049
Activity-guided fractionation based on in vitro assays was used to identify antibacterial components in the residue wasted in the manufacturing process of aged garlic extract (AGE). Antimicrobial activity of the hexane extract of aged garlic-derived
Autor:
Hirotaka Amano, Hiromichi Kawasaki
Publikováno v:
Molecular Medicine Reports
MicroRNAs (miRNAs), a family of small non‑coding RNAs, serve a pivotal role in the regulation of the inflammation by modulating the expression of various genes. However, the molecular mechanism by which miRNAs regulate inflammation‑associated mol
Autor:
Daichi Kazamori, Akira Yazaki, Kensuke Ohishi, Yasuhiro Kuramoto, Hirano Tatsuya, Satoshi Inoue, Kouji Nishimura, Tomohiko Kinoshita, Asuka Sakurai, Hirotaka Amano
Publikováno v:
Chemical and Pharmaceutical Bulletin. 66:235-238
WFQ-101 with a unique N-1 substituent, 5-amino-4-fluoro-2-(hydroxymethyl)phenyl group, was selected as a lead compound through combination screening based on antimicrobial activity and the efflux index against quinolone-resistant (QR) Pseudomonas aer
Autor:
Jun-ichiro Suzuki, Toshiaki Matsutomo, Yukihiro Kodera, Hirotaka Amano, Takako Yamaguchi, Naoaki Morihara
Publikováno v:
Nutrition. 32:884-889
Objectives S -Allylcysteine (SAC) and S -1-propenylcysteine (S1PC) are the characteristic sulfur-containing amino acids in aged garlic extract. In this study, we investigated the effect of SAC and S1PC on intestinal immunoglobulin (Ig)A production to
Publikováno v:
The Journal of Nutrition. 146:456S-459S
Background S-Allylcysteine (SAC) is a key component of aged garlic extract, one of many garlic products. However, information on its pharmacokinetics has been scant except for data from a few animal studies. Objective We designed this study to determ
Publikováno v:
Biological & Pharmaceutical Bulletin. 39:1701-1707
Three major organosulfur compounds of aged garlic extract, S-allyl-L-cysteine (SAC), S-methyl-L-cysteine (SMC), and trans-S-1-propenyl-L-cysteine (S1PC), were examined for their effects on the activities of five major isoforms of human CYP enzymes: C
Publikováno v:
Drug Metabolism and Disposition. 43:749-755
The metabolism, excretion, and pharmacokinetics of S-allyl-l-cysteine (SAC), an active key component of garlic supplements, were examined in rats and dogs. A single dose of SAC was administered orally or i.v. to rats (5 mg/kg) and dogs (2 mg/kg). SAC
Autor:
Daichi Kazamori, Taichi Ueshima, Hirotaka Amano, Akira Yazaki, Kaori Sugimoto, Yasuhiro Kuramoto, Kenji Itoh, Hiroshi Aoi
Publikováno v:
International Journal of Antimicrobial Agents. 44:443-449
The aim of this study was to examine the in vitro antibacterial activity of WQ-3810, a new fluoroquinolone, against clinically relevant pathogens such as Acinetobacter baumannii, Escherichia coli and Streptococcus pneumoniae, including multidrug-resi
Publikováno v:
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 4, p 570 (2017)
Molecules, Vol 22, Iss 4, p 570 (2017)
S-1-Propenyl-l-cysteine (S1PC) is a stereoisomer of S-1-Propenyl-l-cysteine (SAC), an important sulfur-containing amino acid that plays a role for the beneficial pharmacological effects of aged garlic extract (AGE). The existence of S1PC in garlic pr