Zobrazeno 1 - 10 of 58 pro vyhledávání: '"Hirotaka, Kanzaki"'
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Disabling the Nuclear Translocalization of RelA/NF-κB by a Small Molecule Inhibits Triple-Negative Breast Cancer Growth
Autor: Hirotaka Kanzaki, Ramachandran Murali, Hanieh Hossein Nejad Ariani, Xinfeng Zhang, Avradip Chatterjee, Xiaojiang Cui, V. Krishnan Ramanujan, Stacey Chung, Mark I. Greene, Nan Deng
Publikováno v: Breast Cancer : Targets and Therapy
Hirotaka Kanzaki,1 Avradip Chatterjee,1 Hanieh Hossein Nejad Ariani,1 Xinfeng Zhang,2 Stacey Chung,2 Nan Deng,3,4 V Krishnan Ramanujan,4 Xiaojiang Cui,1,2,4 Mark I Greene,5 Ramachandran Murali1 1Department of Biomedical Sciences, Research Division of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262548ae5d9567cde0063ef2d330b79f
https://doi.org/10.2147/bctt.s310231
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3
Akademický článek
Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer.
Autor: Tatsuaki Takeda, Hiromasa Yamamoto, Hirotaka Kanzaki, Ken Suzawa, Takahiro Yoshioka, Shuta Tomida, Xiaojiang Cui, Ramachandran Murali, Kei Namba, Hiroki Sato, Hidejiro Torigoe, Mototsugu Watanabe, Kazuhiko Shien, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Yoshihisa Kitamura, Shinichiro Miyoshi, Toshiaki Sendo, Shinichi Toyooka
Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0171356 (2017)
Overexpression of human epidermal growth factor receptor 2 (HER2) is observed in approximately 15-23% of breast cancers and these cancers are classified as HER2-positive breast cancer. Trastuzumab is the first-line targeted therapeutic drug for HER2-
Externí odkaz: https://doaj.org/article/5b2dfa564e694a529e34914eeba067c8
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4
Akademický článek
Mitochondrial NDUFS3 regulates the ROS-mediated onset of metabolic switch in transformed cells
Autor: Sonal Suhane, Hirotaka Kanzaki, Vaithilingaraja Arumugaswami, Ramachandran Murali, V. Krishnan Ramanujan
Publikováno v: Biology Open, Vol 2, Iss 3, Pp 295-305 (2013)
Summary Aerobic glycolysis in transformed cells is an unique metabolic phenotype characterized by a hyperactivated glycolytic pathway even in the presence of oxygen. It is not clear if the onset of aerobic glycolysis is regulated by mitochondrial dys
Externí odkaz: https://doaj.org/article/7ab64542b2f64da7898f85edf85d4ee1
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5
Akademický článek
Increased DOI-Induced Wet-Dog Shakes in Adrenocorticotropic Hormone–Treated Rats Are Not Affected by Chronic Imipramine Treatment: Possible Involvement of Enhanced 5-HT2A–Receptor Expression in the Frontal Cortex
Autor: Yoshihisa Kitamura, Kazuhiko Shibata, Kozue Akiyama, Shizue Kimoto, Yoshika Fujitani, Kouhei Kitagawa, Hirotaka Kanzaki, Mamoru Ouchida, Kenji Shimizu, Hiromu Kawasaki, Toshiaki Sendo, Yutaka Gomita
Publikováno v: Journal of Pharmacological Sciences, Vol 106, Iss 1, Pp 100-106 (2008)
We examined the influence of imipramine, a traditional tricyclic antidepressant, on the binding to serotonin (5-HT)2receptors and levels of 5-HT2A–receptor mRNA in the frontal cortex of rats treated with adrenocorticotropic hormone (ACTH). Chronic
Externí odkaz: https://doaj.org/article/8396a498c99643dc8648f02bf041ad10
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7
Akademický článek
Truncated SSX protein suppresses synovial sarcoma cell proliferation by inhibiting the localization of SS18-SSX fusion protein.
Autor: Yasushi Yoneda, Sachio Ito, Toshiyuki Kunisada, Yuki Morimoto, Hirotaka Kanzaki, Aki Yoshida, Kenji Shimizu, Toshifumi Ozaki, Mamoru Ouchida
Publikováno v: PLoS ONE, Vol 8, Iss 10, p e77564 (2013)
Synovial sarcoma is a relatively rare high-grade soft tissue sarcoma that often develops in the limbs of young people and induces the lung and the lymph node metastasis resulting in poor prognosis. In patients with synovial sarcoma, specific chromoso
Externí odkaz: https://doaj.org/article/1965736d482341a783474f9663758411
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8
Akademický článek
Novel direct targets of miR-19a identified in breast cancer cells by a quantitative proteomic approach.
Autor: Mamoru Ouchida, Hirotaka Kanzaki, Sachio Ito, Hiroko Hanafusa, Yoshimi Jitsumori, Seiji Tamaru, Kenji Shimizu
Publikováno v: PLoS ONE, Vol 7, Iss 8, p e44095 (2012)
The miR-17-92 cluster encodes 7 miRNAs inside a single polycistronic transcript, and is known as a group of oncogenic miRNAs that contribute to tumorigenesis in several cancers. However, their direct targets remain unclear, and it has been suggested
Externí odkaz: https://doaj.org/article/dc3d92f85bf544598934624cb7f93ab5
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