Výsledky vyhledávání - "Hirotada Yamada"

Autor: Masayuki Mutoh, Masatomo Fukasawa, Hiroshi Nouda, Hideo Nagata, Ueda Shinji, Takao Okuda, Hirotada Yamada

Publikováno v: The Journal of antibiotics. 43(5)

Synthesis and biological properties of esters of a new orally active cephalosporin and related compounds compared with cefixime and cefteram pivoxil.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e314dcef7858dc5ac879b3266177c63f
https://pubmed.ncbi.nlm.nih.gov/2358409

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Studies on β-Lactam Antibiotics. IV. Synthesis of Apalcillin

Autor: Tetsuo Miyazaki, Kosaku Okamura, Hisao Tobiki, Hirotada Yamada, Hiroyuki Suzuki, Norihiko Tanno, Kozo Shimago, Ueda Shinji

Publikováno v: YAKUGAKU ZASSHI. 100:49-55

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ffce86a32fb663095c55bc49333e90ab
https://doi.org/10.1248/yakushi1947.100.1_49

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Studies on β-Lactam Antibiotics. III. Synthesis of 6-[D (-)-α-(Acylamino)-phenylacetamido] penicillanic Acids and Antibacterial Activity

Autor: HISAO TOBIKI, HIROTADA YAMADA, IWAO NAKATSUKA, KOZO SHIMAGO, YASUKO EDA, HIROSHI NOGUCHI, TOSHIAKI KOMATSU, TAKENARI NAKAGOME

Publikováno v: YAKUGAKU ZASSHI. 100:38-48

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6e5bb6a4755e7d9a32ba2638a673179
https://doi.org/10.1248/yakushi1947.100.1_38

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New broad-spectrum cephalosporins with anti-pseudomonal activity. III. Synthesis and antibacterial activity of 7 beta-[D-2-(4-hydroxy-6-methylpyridine-3-carbonylamino)-2-(4-hydroxyphenyl) acetamido]-3-(methyl or substituted methyl)-ceph-3-em-4-carboxylic acids

Autor: Takenari Nakagome, Toshiaki Komatsu, Hisao Tobiki, Kiyokazu Jimpo, Takao Okuda, Hiroshi Noguchi, Hirotada Yamada

Publikováno v: The Journal of antibiotics. 36(5)

The influence of various 3-substituents on the antibacterial activity of 7 beta-[D-2-(4-hydroxy-6-methylpyridine-3-carbonylamino)-2-(4-hydroxyphenyl) acetamido]ceph-3-em-4-carboxylic acids (III) was investigated. Introduction of an acidic substituent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb1952c54fbe2881c9cd92285bce3b1
https://pubmed.ncbi.nlm.nih.gov/6409870

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New broad-spectrum cephalosporins with anti-pseudomonal activity. II. Synthesis and antibacterial activity of 7 beta-[2-acylamino-2-(4-hydroxyphenyl)acetamido]-3-[ (1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acids

Autor: Toshiaki Komatsu, Hisao Tobiki, Kiyokazu Jimpo, Hirotada Yamada, Takenari Nakagome, Takeuchi Yutaka, Hiroshi Noguchi, Takao Okuda, Koushiro Gooda, Ueda Shinji, Kenji Irie

Publikováno v: The Journal of antibiotics. 36(5)

The influence of the chirality of the 7-acyl side chain and of various N-acyl moieties (A-CO-) on the in vitro activity of 7 beta-[2-acylamino-2-(4-hydroxyphenyl)acetamido ]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acids (6) wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a058a5618f7b517ceff6209a9d2fef
https://pubmed.ncbi.nlm.nih.gov/6409869

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New broad-spectrum cephalosporins with anti-pseudomonal activity. I. Synthesis and antibacterial activity of 7 beta-[D-2-[(4-hydroxy-1,5-naphthyridine-3-carbonylamino)- and (4-hydroxypyridine-3-carbonylamino)]-2-(4-hydoxyphenyl)acetamido] cephalosporins

Autor: Takenari Nakagome, Hirotada Yamada, Kiyokazu Jimpo, Kenji Irie, Toshiaki Komatsu, Hiroshi Noguchi, Hisao Tobiki

Publikováno v: The Journal of antibiotics. 36(5)

The synthesis and the antibacterial activity of 7 beta-[D-2-[(4-hydroxy-1,5-naphthyridine-3-carbonylamino)- and (4-hydroxypyridine-3-carbonylamino)]-2-(4-hydroxyphenyl)acetamido]-cephalosporins with various substituents at the 3-position in the cephe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb74322d77d4cc7348ac7ebc45b0bb85
https://pubmed.ncbi.nlm.nih.gov/6409868

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Deprotection of 4-Methoxybenzyloxycarbonyl Group withp-Toluenesulfonic Acid in Acetonitrile. Application to a Large-scale Preparation of 7-[D-2-Amino-2-(4-hydroxyphenyl)acetamido]cephalosporanic Acid

Autor: Ueda Shinji, Hirotada Yamada, Takenari Nakagome, Hiroyuki Suzuki, Hisao Tobiki, Kiyokazu Jimpo, Norihiko Tanno

Publikováno v: Bulletin of the Chemical Society of Japan. 57:3333-3334

The 4-methoxybenzyloxycarbonyl group of 7-[D-2-(4-hydroxyphenyl)-2-(4-methoxybenzyloxycarbonylamino)acetamido]cephalosporanic acid was effectively removed with p-toluenesulfonic acid in acetonitrile. The mechanism of the deprotection is discussed and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9db8d4fb29d091d481b7f21a0353966
https://doi.org/10.1246/bcsj.57.3333

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