Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hirotada, Kojima"'
Autor:
Takahito Ohira, Hirotada Kojima, Yuko Kuroda, Sayaka Aoki, Daigo Inaoka, Mitsuhiko Osaki, Hideki Wanibuchi, Futoshi Okada, Mitsuo Oshimura, Hiroyuki Kugoh
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0217605 (2019)
Telomerase is a ribonucleoprotein ribonucleic enzyme that is essential for cellular immortalization via elongation of telomere repeat sequences at the end of chromosomes. Human telomerase reverse transcriptase (hTERT), the catalytic subunit of telome
Externí odkaz:
https://doaj.org/article/ae0eafbb777743f0b6ccad79149212d0
Autor:
Ling-Yu Wang, Masatsugu Kimura, Hiroyuki Kunimoto, Tokio Tani, Takahiro Yamamoto, Naoki Yamamoto, Sheng-Jun Xiao, Hong Zhao, Hirotada Kojima, Kishiko Sunami, Koji Nishio, Kazuaki Tokunaga, Koichi Nakajima, Akira Inoue
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10526, p 10526 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10526, p 10526 (2021)
RBM10 is an RNA-binding protein that regulates alternative splicing (AS). It localizes to the extra-nucleolar nucleoplasm and S1-1 nuclear bodies (NBs) in the nucleus. We investigated the biological significance of this localization in relation to it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d270894dae4454d7d35e02d681b0bcdf
Autor:
Daisuke Tsuruta, Hong Zhao, Hiroyuki Kunimoto, Koichi Nakajima, Junhao Yang, Akira Inoue, Hirotada Kojima
Publikováno v:
Genes to cells : devoted to molecularcellular mechanismsREFERENCES. 25(2)
RNA-binding motif protein 10 (RBM10) primarily regulates alternative splicing of certain genes. Loss-of-function mutations in RBM10 have been frequently reported in patients with various cancers. However, how RBM10 levels affect cell proliferation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b292cb53e5a6da2ec77173e288821281
https://pubmed.ncbi.nlm.nih.gov/31820547
https://pubmed.ncbi.nlm.nih.gov/31820547
Autor:
Mitsuhiko Osaki, Hirotada Kojima, Takahito Ohira, Hiroyuki Kugoh, Hideki Wanibuchi, Daigo Inaoka, Yuko Kuroda, Futoshi Okada, Mitsuo Oshimura
Telomerase is a ribonucleoprotein ribonucleic enzyme that is essential for cellular immortalization via elongation of telomere repeat sequences at the end of chromosomes. Human telomerase reverse transcriptase (hTERT), the catalytic subunit of telome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131308889dbd7d3858315579ea884e83
Autor:
Hideki Wanibuchi, Takahito Ohira, Mitsuo Oshimura, Mitsuhiko Osaki, Daigo Inaoka, Yuko Kuroda, Hiroyuki Kugoh, Futoshi Okada, Sayaka Aoki, Hirotada Kojima
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 8, p e0217605 (2019)
PLoS ONE, Vol 14, Iss 8, p e0217605 (2019)
Telomerase is a ribonucleoprotein ribonucleic enzyme that is essential for cellular immortalization via elongation of telomere repeat sequences at the end of chromosomes. Human telomerase reverse transcriptase (hTERT), the catalytic subunit of telome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fff59d376aa0ecce8262518f8c69b3c
https://pubmed.ncbi.nlm.nih.gov/31404068
https://pubmed.ncbi.nlm.nih.gov/31404068
Autor:
Yanze Li, Motonobu Katoh, Toshiaki Inoue, Yuji Nakayama, Hideki Wanibuchi, Haruka Matsumori, Haruka Takahashi, Mitsuo Oshimura, Hirotada Kojima
Publikováno v:
FEBS Journal. 281:2623-2637
Mitotic catastrophe, a form of cell death that occurs during mitosis and after mitotic slippage to a tetraploid state, plays important roles in the efficacy of cancer cell killing by microtubule inhibitors (MTIs). Prolonged mitotic arrest by the spin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf0dbf3913fc4dd7b2255a389e3ba35
https://doi.org/10.1111/febs.12810
https://doi.org/10.1111/febs.12810
Publikováno v:
Cell Cycle. 11:730-739
Cells undergo senescence in response to various conditions, including telomere erosion, oncogene activation and multiple cytokines. One of these cytokines, interleukin-6 (IL‑6), not only functions in the immune system, but also promotes cellular se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9164e7fab5ee077619fe67301fae1943
https://doi.org/10.4161/cc.11.4.19172
https://doi.org/10.4161/cc.11.4.19172
Autor:
Akira Inoue, Koichi Nakajima, Kanae Tanino, Hirotada Kojima, Hiroyuki Kunimoto, Ryohei Wakahara, Haruo Shintaku
Publikováno v:
Genes to Cells. 17:132-145
Signal transducer and activator of transcription 3 (STAT3) is a latent cytoplasmic transcription factor. It is activated by cytokines, including interleukin-6 (IL-6) through phosphorylation at Tyr705 (pY705), which is required for its dimerization an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a7fced5f6b31c7d5afc155bf265fa1a
https://doi.org/10.1111/j.1365-2443.2011.01575.x
https://doi.org/10.1111/j.1365-2443.2011.01575.x
Autor:
Motonobu Katoh, Toshiaki Inoue, Mitsuhiko Osaki, Yanze Li, Haruka Matsumori, Seiichi Mori, Akihiro Kurimasa, Mitsuo Oshimura, Hisao Ito, Hirotada Kojima, Yuji Nakayama
Publikováno v:
Genes to Cells. 16:34-45
We previously reported that sirtuin 2 (SIRT2), a mammalian member of the NAD+-dependent protein deacetylases, participates in mitotic regulation, specifically, in efficient mitotic cell death caused by the spindle checkpoint. Here, we describe a nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f449796dc4218de0a3b2e2fb1e3f3319
https://doi.org/10.1111/j.1365-2443.2010.01460.x
https://doi.org/10.1111/j.1365-2443.2010.01460.x
Autor:
Toshio Hirano, Kazuto Nakae, Koichi Nakajima, Tadashi Matsuda, Takashi Takeda, Yoshio Fujitani, Yojiro Yamanaka, Hirotada Kojima
Publikováno v:
Annals of the New York Academy of Sciences. 762:55-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d46fcd09b09057eba3778764481ffc
https://doi.org/10.1111/j.1749-6632.1995.tb32314.x
https://doi.org/10.1111/j.1749-6632.1995.tb32314.x