Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Hiroshi Wakui"'
Autor:
Masahiro Torasawa, Hidehito Horinouchi, Shigehiro Yagishita, Hirofumi Utsumi, Keitaro Okuda, Daisuke Takekoshi, Saburo Ito, Hiroshi Wakui, Saori Murata, Sawako Kaku, Kae Okuma, Yuji Matsumoto, Yuki Shinno, Yusuke Okuma, Tatsuya Yoshida, Yasushi Goto, Noboru Yamamoto, Jun Araya, Yuichiro Ohe, Yu Fujita
Publikováno v:
Thoracic Cancer, Vol 14, Iss 29, Pp 2909-2923 (2023)
Abstract Background Risk factors for predicting pneumonitis during durvalumab consolidation after chemoradiotherapy (CRT) in locally advanced non‐small cell lung cancer (LA‐NSCLC) are still lacking. Extracellular vesicles (EVs) play a crucial rol
Externí odkaz:
https://doaj.org/article/c26bd9ec8eaf4da5b06f23bbc99b43dc
Autor:
Masahiro Yoshida, Shunsuke Minagawa, Jun Araya, Taro Sakamoto, Hiromichi Hara, Kazuya Tsubouchi, Yusuke Hosaka, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota, Nahoko Sato, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Hirohumi Utsumi, Hiroshi Wakui, Takanori Numata, Yumi Kaneko, Shohei Mori, Hisatoshi Asano, Makoto Yamashita, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama, Takeo Iwamoto, Hirotaka Imai, Kazuyoshi Kuwano
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Altered iron homeostasis resulting in excessive oxidative stress has been implicated in smoke-induced lung diseases. Here the authors show that ferroptosis of lung epithelial cells, potentially resulting from excessive ferritinophagy, is involved in
Externí odkaz:
https://doaj.org/article/7f973dabdbee4e05bfa82fda5c334da7
Autor:
Hiromichi Hara, Keitaro Okuda, Jun Araya, Hirofumi Utsumi, Daisuke Takekoshi, Saburo Ito, Hiroshi Wakui, Shunsuke Minagawa, Takanori Numata, Kazuyoshi Kuwano
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261866 (2021)
ObjectivesRecently, incidence of Mycobacterium abscessus (Mab) pulmonary disease (Mab-PD) is increasing worldwide. We aimed to identify factors associated with severity of Mycobacterium abscessus (Mab) pulmonary disease (Mab-PD).MethodsAll patients d
Externí odkaz:
https://doaj.org/article/bcbcf424e87046ddbd4b10b74153fd55
Autor:
Takanori Numata, Katsutoshi Nakayama, Satoko Fujii, Yoko Yumino, Nayuta Saito, Masahiro Yoshida, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara, Jun Araya, Yumi Kaneko, Kazuyoshi Kuwano
Publikováno v:
BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Postoperative pulmonary complications (PPC) in patients with pulmonary diseases remain to be resolved clinical issue. However, most evidence regarding PPC has been established more than 10 years ago. Therefore, it is necessary to
Externí odkaz:
https://doaj.org/article/d3b90ddb33734d108fc053a57367d64e
Autor:
Yutaka Yoshii, Kenichiro Shimizu, Miyuki Morozumi, Naoko Chiba, Kimiko Ubukata, Hironori Uruga, Shigeo Hanada, Hiroshi Wakui, Shunsuke Minagawa, Hiromichi Hara, Takanori Numata, Keisuke Saito, Jun Araya, Katsutoshi Nakayama, Kazuma Kishi, Kazuyoshi Kuwano
Publikováno v:
BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Respiratory tract infection is a major cause of acute exacerbation of bronchial asthma (AEBA). Although recent findings suggest that common bacteria are causally associated with AEBA, a comprehensive epidemiologic analysis of infe
Externí odkaz:
https://doaj.org/article/ff058a359a9349369decdd7bab8c153a
Autor:
Yusuke Kurita, Jun Araya, Shunsuke Minagawa, Hiromichi Hara, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota, Kazuya Tsubouchi, Nahoko Sato, Masahiro Yoshida, Kenji Kobayashi, Saburo Ito, Yu Fujita, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Yutaka Yoshii, Takeo Ishikawa, Takanori Numata, Yumi Kaneko, Hisatoshi Asano, Makoto Yamashita, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama, Kazuyoshi Kuwano
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Pirfenidone (PFD) is an anti-fibrotic agent used to treat idiopathic pulmonary fibrosis (IPF), but its precise mechanism of action remains elusive. Accumulation of profibrotic myofibroblasts is a crucial process for fibrotic remod
Externí odkaz:
https://doaj.org/article/1146926490a44a5c8c9022cb1d7ba748
Fibroblast-Derived Extracellular Vesicles Induce Lung Cancer Progression in the IPF Microenvironment
Autor:
Yu Fujita, Shota Fujimoto, Atsushi Miyamoto, Reika Kaneko, Tsukasa Kadota, Naoaki Watanabe, Ryusuke Kizawa, Hironori Kawamoto, Junko Watanabe, Hirofumi Utsumi, Hiroshi Wakui, Shunsuke Minagawa, Jun Araya, Takashi Ohtsuka, Takahiro Ochiya, Kazuyoshi Kuwano
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0517c735035f6ab9242f55653d3834d2
https://doi.org/10.1165/rcmb.2022-0253oc
https://doi.org/10.1165/rcmb.2022-0253oc
Publikováno v:
Calculus of Variations and Partial Differential Equations. 62
We show the finite time blow up of a solution to the Cauchy problem of a drift-diffusion equation of a parabolic-elliptic type in higher space dimensions. If the initial data satisfies a certain condition involving the entropy functional, then the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ed3058ad75cac9a95e93bebb99f7b98
https://doi.org/10.1007/s00526-022-02345-x
https://doi.org/10.1007/s00526-022-02345-x
Publikováno v:
Journal of Evolution Equations. 21:4873-4896
The Cauchy problem for the parabolic--elliptic Keller--Segel system in the whole $n$-dimensional space is studied. For this model, every constant $A \in \mathbb{R}$ is a stationary solution. The main goal of this work is to show that $A < 1$ is a sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42723d922a209295b7a1923ed1beb131
https://doi.org/10.1007/s00028-021-00735-w
https://doi.org/10.1007/s00028-021-00735-w
Autor:
Yu Fujita, Shota Fujimoto, Atsushi Miyamoto, Reika Kaneko, Tsukasa Kadota, Naoaki Watanabe, Ryusuke Kizawa, Hironori Kawamoto, Junko Watanabe, Hirofumi Utsumi, Hiroshi Wakui, Shunsuke Minagawa, Jun Araya, Takashi Ohtsuka, Takahiro Ochiya, Kazuyoshi Kuwano
Publikováno v:
American Journal of Respiratory Cell & Molecular Biology; Jul2023, Vol. 69 Issue 1, p34-E15, 26p