Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hiroshi Uejima"'
Autor:
Hiroshi Uejima, Yoshiki Katou, Yuji Kawamata, Shumpei Murata, Kuniko Kikuchi, Satoru Matsumoto, Kentaro Otake, Mika Teratani, Yasutaka Hoashi, Kenjo Eriya, Masahiro Nogami, Yukimasa Makita
Publikováno v:
Biochemical and Biophysical Research Communications. 493:800-806
Hepatocellular carcinoma (HCC) is still one of the major causes of cancer-related death. Kinetochore-associated protein 2 (KNTC2) is specifically upregulated in tumor tissues of HCC patients and recognized as a potential candidate target for the trea
Autor:
Kanato Yamagata, Hidekazu Tanaka, Saya Nakagomi, Ryuichi Ohgaki, Shushi Nagamori, Akira Oda, Yoshikatsu Kanai, Pattama Wiriyasermkul, Hiroshi Uejima
Publikováno v:
Journal of Neurochemistry. 128:246-255
Cholinergic neurons in the CNS are involved in synaptic plasticity and cognition. Both muscarinic and nicotinic acetylcholine receptors (nAChRs) influence plasticity and cognitive function. The mechanism underlying nAChR-induced plasticity, however,
Publikováno v:
Commun. Inf. Syst. 04, no. 4 (2004), 273-288
Recently there have been a lot of researches for summarizing news stream and for detecting edges of new events in the news stream. But, in these tasks, all data are assumed to carry timestamp (temporal information). It is noteworthy that news article
Autor:
Yasuhiro Tanaka, Masahiko Fujino, Yukio Fujisawa, Rie Satoh, Shoichi Okubo, Hideyuki Tanaka, Kazuhiro Ogi, Ryo Fujii, Minoru Maruyama, Shuji Hinuma, Masataka Harada, Hiroshi Uejima, Tokuyuki Shinohara, Yasuaki Itoh, Hidetoshi Komatsu, Yuji Kawamata, Shoji Fukusumi, Masaki Hosoya, Makoto Kobayashi, Hideki Kizawa, Yuko Noguchi, Fumika Matsumura
Publikováno v:
Nature. 422:173-176
Diabetes, a disease in which carbohydrate and lipid metabolism are regulated improperly by insulin, is a serious worldwide health issue. Insulin is secreted from pancreatic beta cells in response to elevated plasma glucose, with various factors modif
Autor:
Hiroshi Uejima, Tomoko Maruyama, Yoshinori Murakami, Mitsuo Oshimura, Hiroshi Fukuhara, Takao Sekiya
Publikováno v:
Journal of Human Genetics. 45:370-373
The introduction of chromosome 10p into human glioblastoma or prostate cancer cells has been demonstrated to suppress their malignant phenotype, suggesting the presence of glioma or prostate tumor suppressor genes on 10p. As a resource for the fine m
Autor:
Tokuyuki Shinohara, Hiroshi Uejima, Isao Ishida, Atsuko Ohguma, Kazuma Tomizuka, Kaoru Sato, Mitsuo Oshimura, Sonoko Tanaka, Hitoshi Yoshida
Publikováno v:
Proceedings of the National Academy of Sciences. 97:722-727
The use of a human chromosome or its fragment as a vector for animal transgenesis may facilitate functional studies of large human genomic regions. We describe here the generation and analysis of double trans-chromosomic (Tc) mice harboring two indiv
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 442
Recent studies have revealed that Argonaute proteins are crucial components of the RNA-induced silencing complexes (RISCs) that direct both small interfering RNA (siRNA)- and microRNA (miRNA)-mediated gene silencing. Full complementarity between the
Publikováno v:
Methods in Molecular Biology™ ISBN: 9781588298744
Recent studies have revealed that Argonaute proteins are crucial components of the RNA-induced silencing complexes (RISCs) that direct both small interfering RNA (siRNA)- and microRNA (miRNA)-mediated gene silencing. Full complementarity between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09da368ff0933d8df999312b494297c8
https://doi.org/10.1007/978-1-59745-191-8_3
https://doi.org/10.1007/978-1-59745-191-8_3
Autor:
Michiko Hayasaka, Isao Ishida, Atsuko Ohguma, Hiroyuki Kugoh, Mitsuo Oshimura, Kazunori Hanaoka, Hitoshi Yoshida, K. Satoh, Kazuma Tomizuka, Hiroshi Uejima
Publikováno v:
New Developments and New Applications in Animal Cell Technology ISBN: 0792350162
A human chromosome or its subchromosomal fragment (SCF) derived from normal fibroblasts was introduced into mouse embryonic stem (ES) cells via microcell-mediated chromosome transfer (MMCT) and viable chimaeric mice were produced from them. Serum ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7ab4f4def9db0023f2dc588b4b39a56
https://doi.org/10.1007/0-306-46860-3_140
https://doi.org/10.1007/0-306-46860-3_140
Autor:
Hitoshi Yoshida, Isao Ishida, Mitsuo Oshimura, Atsuko Ohguma, Kazuma Tomizuka, K. Satoh, Hiroshi Uejima
Publikováno v:
Animal Cell Technology: Basic & Applied Aspects ISBN: 0792354516
Monoclonal antibodies are not only used in human diagnostics, but also in human therapy. People cannnot be immunized in vivo with any kind of antigen, and many challenges have been done to obtain human monoclonal antibodies for therapeutic use. Trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e858bbf5120bfd2c9c3d19deafd392b
https://doi.org/10.1007/0-306-46865-4_12
https://doi.org/10.1007/0-306-46865-4_12