Zobrazeno 1 - 10
of 1 788
pro vyhledávání: '"Hiroshi Ueda"'
Autor:
Yusuke Anan, Masanori Itakura, Tatsuya Shimoda, Kosuke Yamaguchi, Peng Lu, Koji Nagata, Jinhua Dong, Hiroshi Ueda, Koji Uchida
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Anti-DNA antibodies (Abs), serological hallmarks of systemic lupus erythematosus (SLE) and markers for diagnosis and disease activity, show a specificity for non-nucleic acid molecules, such as N-pyrrolated proteins (pyrP) containing N ε-py
Externí odkaz:
https://doaj.org/article/aa1585d17d0e48099497241c9a3e3599
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 949 (2024)
Polymorphic control is vital for the quality control of pharmaceutical crystals. Here, we investigated the relationship between the hydrate and anhydrate polymorphs of a monoacylglycerol acyltransferase 2 inhibitor (S-309309). Solvent evaporation and
Externí odkaz:
https://doaj.org/article/68380e306faf4b05b3caae6d3f865fca
Autor:
Hiroshi Ueda, Hiroyuki Neyama
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 56 (2023)
Fibromyalgia (FM) is a chronic pain condition characterized by widespread musculoskeletal pain and other frequent symptoms such as fatigue, sleep disturbance, cognitive impairment, and mood disorder. Based on the view that intermittent stress would b
Externí odkaz:
https://doaj.org/article/d43991a6e5b3438887cb10d8e30836b1
Publikováno v:
ADMET and DMPK, Vol 11, Iss 3 (2023)
Background and purpose: Physicochemical properties of an amorphous solid dispersion (ASD) comprising an experimental grade of hydroxypropyl methylcellulose acetate succinate (HPMCAS-MX) with lower glass transition temperature have been previously inv
Externí odkaz:
https://doaj.org/article/91db14a807b4458882e5479d33634230
Autor:
Haimei Li, Bo Zhu, Baowei Li, Limei Chen, Xuerao Ning, Hang Dong, Jingru Liang, Xueying Yang, Jinhua Dong, Hiroshi Ueda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Since late 2019, the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the resultant spread of COVID-19 have given rise to a worldwide health crisis that is posing great challenges to public health and clinical tre
Externí odkaz:
https://doaj.org/article/85ab7d6f44cc40ae848fecbe0884f4f7
Autor:
Mai Takizawa, Yuri Osuga, Rika Ishida, Marie Mita, Kazuki Harada, Hiroshi Ueda, Tetsuya Kitaguchi, Takashi Tsuboi
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
A red fluorescent protein-based indicator of cyclic guanosine 3′, 5′-monophosphate (cGMP) allows for multi-colour imaging and optogenetic applications while monitoring cGMP activity in cells.
Externí odkaz:
https://doaj.org/article/8235020990e142d49fc77db5453efb48
Autor:
Hiroshi Ueda, Hee-Jin Jeong
Publikováno v:
Methods and Protocols, Vol 6, Iss 5, p 90 (2023)
Development of a rapid detection method for deoxycholic acid (DCA) is crucial for its diagnosis in the early stages of inflammation and cancer. In this study, we expressed a soluble recombinant anti-DCA single-chain variable fragment (scFv) in Escher
Externí odkaz:
https://doaj.org/article/c51f07fcf0de4d7f900111404b753a72
Autor:
Hiroshi Ueda
Publikováno v:
Cells, Vol 12, Iss 12, p 1569 (2023)
Nuclear protein prothymosin α (ProTα) is a unique member of damage-associated molecular patterns (DAMPs)/alarmins. ProTα prevents neuronal necrosis by causing a cell death mode switch in serum-starving or ischemic/reperfusion models in vitro and i
Externí odkaz:
https://doaj.org/article/060bb517d834470daf36805af4028c45
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Quenchbody (Q-body) is a quench-based fluorescent immunosensor labeled with fluorescent dye(s) near the antigen-binding site of an antibody. Q-bodies can detect a range of target molecules rapidly and directly. However, because Q-bodies show
Externí odkaz:
https://doaj.org/article/a20366beae274f73bea2559c07411a51
Autor:
Haimei Li, Xinyu Li, Limei Chen, Baowei Li, Hang Dong, Hongying Liu, Xueying Yang, Hiroshi Ueda, Jinhua Dong
Publikováno v:
ACS Omega, Vol 6, Iss 46, Pp 31009-31016 (2021)
Externí odkaz:
https://doaj.org/article/06658f96e3d848449b89e80ed0ba5955