Zobrazeno 1 - 10
of 372
pro vyhledávání: '"Hiroshi Uchi"'
Autor:
Kenjiro Namikawa, Takamichi Ito, Shusuke Yoshikawa, Koji Yoshino, Yukiko Kiniwa, Shuichi Ohe, Taiki Isei, Tatsuya Takenouchi, Hiroshi Kato, Satoru Mizuhashi, Satoshi Fukushima, Yosuke Yamamoto, Takashi Inozume, Yasuhiro Fujisawa, Osamu Yamasaki, Yasuhiro Nakamura, Jun Asai, Takeo Maekawa, Takeru Funakoshi, Shigeto Matsushita, Eiji Nakano, Kohei Oashi, Junji Kato, Hisashi Uhara, Takuya Miyagawa, Hiroshi Uchi, Naohito Hatta, Keita Tsutsui, Taku Maeda, Taisuke Matsuya, Hiroto Yanagisawa, Ikko Muto, Mao Okumura, Dai Ogata, Naoya Yamazaki
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 17967-17980 (2023)
Abstract Background Anti‐PD‐1‐based immunotherapy is considered a preferred first‐line treatment for advanced BRAF V600‐mutant melanoma. However, a recent international multi‐center study suggested that the efficacy of immunotherapy is po
Externí odkaz:
https://doaj.org/article/7bd38e76e920444a8356acd6025d9a4c
Autor:
Yusuke Muto, Yumi Kambayashi, Hiroshi Kato, Satoru Mizuhashi, Takamichi Ito, Takeo Maekawa, Shoichiro Ishizuki, Hiroshi Uchi, Shigeto Matsushita, Yuki Yamamoto, Koji Yoshino, Yasuhiro Fujisawa, Ryo Amagai, Kentaro Ohuchi, Akira Hashimoto, Satoshi Fukushima, Yoshihide Asano, Taku Fujimura
Publikováno v:
Cancers, Vol 16, Iss 15, p 2755 (2024)
Background: Adjuvant therapy has improved the clinical prognosis for postoperative melanoma patients. However, the long-term efficacy of this therapy on the melanoma acral and mucosal subtypes has not been fully evaluated in previous trials. This stu
Externí odkaz:
https://doaj.org/article/1263fcf599ec44d1a321e84f93e22d4a
Autor:
Yusuke Muto, Yumi Kambayashi, Hiroshi Kato, Satoshi Fukushima, Takamichi Ito, Takeo Maekawa, Yasuhiro Fujisawa, Koji Yoshino, Hiroshi Uchi, Shigeto Matsushita, Yuki Yamamoto, Ryo Amagai, Kentaro Ohuchi, Akira Hashimoto, Taku Fujimura
Publikováno v:
Acta Dermato-Venereologica, Vol 102 (2022)
Anti-PD-1 antibodies (Abs) are among the optimal adjuvant therapies for melanoma at high risk of recurrence, especially BRAF wild-type melanoma, but the anti-tumour effects of anti-PD-1 Abs in the adjuvant setting for acral melanoma have not been eva
Externí odkaz:
https://doaj.org/article/fa5b1bbbd6dc44ed9313f06675f9d562
Autor:
Yasuhiro Fujisawa, Shusuke Yoshikawa, Akane Minagawa, Tatsuya Takenouchi, Kenji Yokota, Hiroshi Uchi, Naoki Noma, Yasuhiro Nakamura, Jun Asai, Junji Kato, Susumu Fujiwara, Satoshi Fukushima, Jiro Uehara, Toshihiko Hoashi, Tatsuya Kaji, Taku Fujimura, Kenjiro Namikawa, Manabu Yoshioka, Naoki Murao, Dai Ogata, Kanako Matsuyama, Naohito Hatta, Yoshitsugu Shibayama, Toshiharu Fujiyama, Masashi Ishikawa, Daisuke Yamada, Akiko Kishi, Yoshiyuki Nakamura, Takatoshi Shimiauchi, Kazuyasu Fujii, Manabu Fujimoto, Hironobu Ihn, Norito Katoh
Publikováno v:
Cancer Medicine, Vol 8, Iss 5, Pp 2146-2156 (2019)
Abstract Background The incidence of melanoma among those of an Asian ethnicity is lower than in Caucasians; few large‐scale Asian studies that include follow‐up data have been reported. Objectives To investigate the clinical characteristics of J
Externí odkaz:
https://doaj.org/article/802d78882fa24ba7ba61619140790c43
Autor:
Seiichi Yano, Kenji Ashida, Hiromi Nagata, Kenji Ohe, Naoko Wada, Yukina Takeichi, Yuki Hanada, Yuta Ibayashi, Lixiang Wang, Shohei Sakamoto, Ryuichi Sakamoto, Hiroshi Uchi, Motoaki Shiratsuchi, Masutaka Furue, Masatoshi Nomura, Yoshihiro Ogawa
Publikováno v:
BMC Endocrine Disorders, Vol 18, Iss 1, Pp 1-6 (2018)
Abstract Background Nivolumab, an anti-programmed cell death-1 monoclonal antibody, has improved the survival of patients with malignant melanoma. Despite its efficacy, nivolumab inconsistently induces thyroid dysfunction as an immune-related adverse
Externí odkaz:
https://doaj.org/article/5bd2e9d380954684be3d0d0d2083d326
Autor:
Kazuhisa Furue, Kazuhiko Yamamura, Gaku Tsuji, Chikage Mitoma, Hiroshi Uchi, Takeshi Nakahara, Makiko Kido-Nakahara, Takafumi Kadono, Masutaka Furue
Publikováno v:
Acta Dermato-Venereologica, Vol 98, Iss 1, Pp 5-13 (2017)
Plaque psoriasis and pustular psoriasis are overlapping, but distinct, disorders. The therapeutic response to biologics supports the pivotal role of the tumour necrosis alpha (TNF-?)/ interleukin (IL)-23/IL-17/IL-22 axis in the pathogenesis of these
Externí odkaz:
https://doaj.org/article/0ea2ee234a3f43c3a23b51db8f1c4772
Autor:
Taku Fujimura, Yota Sato, Kayo Tanita, Chunbing Lyu, Yumi Kambayashi, Ryo Amagai, Atsushi Otsuka, Yasuhiro Fujisawa, Koji Yoshino, Shigeto Matsushita, Hiroshi Uchi, Yuki Yamamoto, Hiroo Hata, Takeru Funakoshi, Yumi Nonomura, Ryota Tanaka, Hisako Okuhira, Naoko Wada, Akira Hashimoto, Setsuya Aiba
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Anti-programmed cell death protein 1 (PD1) antibodies are in wide use for the treatment of various cancers. PD1 antibody-based immunotherapy, co-administration of nivolumab and ipilimumab, is one of the optimal immunotherapies, especially in advanced
Externí odkaz:
https://doaj.org/article/60775cb304df4e02a56684d41b7ab84f
Autor:
Hiroshi Uchi
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer with frequent metastasis and death. MCC has a mortality rate of 30%, making it more lethal than malignant melanoma, and incidence of MCC has increased almost fourfold over the past 20 y
Externí odkaz:
https://doaj.org/article/10157d1a62124471ba234f224ecf758f
Autor:
Yuki Kuma, Takamichi Ito, Konosuke Nagae, Yukihiro Mizote, Takeshi Nakahara, Hiroshi Uchi, Yuichi Yamada, Masae Okura, Yoshinao Oda, Toshiharu Yamashita, Masutaka Furue
Publikováno v:
Case Reports in Dermatology, Vol 7, Iss 2, Pp 178-182 (2015)
Increasing evidence has suggested that human papillomaviruses (HPVs) are linked to a large subset of numerous malignant tumors, including mucosal squamous cell carcinoma (SCC); however, its involvement in cutaneous SCC has not fully been elucidated.
Externí odkaz:
https://doaj.org/article/a0427e5021e34292bc52fa6b9369dff5
Publikováno v:
Case Reports in Dermatology, Vol 6, Iss 2, Pp 140-144 (2014)
Spindle cell melanoma, which is a rare form of melanoma, is clinically and histopathologically difficult to diagnose from a variety of nonmelanocytic spindle cell tumors. We describe a 42-year-old Japanese woman with amelanotic melanoma that comprise
Externí odkaz:
https://doaj.org/article/0b1daf6e0b224855ab2dbaff9b9c8eff