Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Hiroshi Taoka"'
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Akademický článek
Leukoaraiosis significantly worsens driving performance of ordinary older drivers.
Autor: Kimihiko Nakano, Kaechang Park, Rencheng Zheng, Fang Fang, Masanori Ohori, Hiroki Nakamura, Yasuhiho Kumagai, Hiroshi Okada, Kazuhiko Teramura, Satoshi Nakayama, Akinori Irimajiri, Hiroshi Taoka, Satoshi Okada
Publikováno v: PLoS ONE, Vol 9, Iss 10, p e108333 (2014)
BACKGROUND: Leukoaraiosis is defined as extracellular space caused mainly by atherosclerotic or demyelinated changes in the brain tissue and is commonly found in the brains of healthy older people. A significant association between leukoaraiosis and
Externí odkaz: https://doaj.org/article/4496379db91e4be4881347734a9f2f93
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2
Inhibition of splicing and nuclear retention of pre-mRNA by spliceostatin A in fission yeast
Autor: Akihisa Matsuyama, Shinichi Nishimura, Chor Wai Lo, Sueharu Horinouchi, Daisuke Kaida, Hidenori Nakajima, Minoru Yoshida, Hiroshi Taoka, Yoko Yashiroda, Hidenori Watanabe, Tokio Tani, Ken Ishigami
Publikováno v: Biochemical and Biophysical Research Communications. 364:573-577
Nuclear retention of pre-mRNAs is tightly regulated by several security mechanisms that prevent pre-mRNA export into the cytoplasm. Recently, spliceostatin A, a methylated derivative of a potent antitumor microbial metabolite FR901464, was found to c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45054e79ce61534ce820834cf8092754
https://doi.org/10.1016/j.bbrc.2007.10.029
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4
Leukoaraiosis significantly worsens driving performance of ordinary older drivers
Autor: Yasuhiho Kumagai, Rencheng Zheng, Kazuhiko Teramura, Kimihiko Nakano, Masanori Ohori, Satoshi Nakayama, Kaechang Park, Hiroshi Taoka, Satoshi Okada, Hiroki Nakamura, Hiroshi Okada, Fang Fang, Akinori Irimajiri
Publikováno v: PLoS ONE, Vol 9, Iss 10, p e108333 (2014)
PLoS ONE
BACKGROUND: Leukoaraiosis is defined as extracellular space caused mainly by atherosclerotic or demyelinated changes in the brain tissue and is commonly found in the brains of healthy older people. A significant association between leukoaraiosis and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32769a1f871bb765d9dfdda03f4fc15
http://europepmc.org/articles/PMC4189976?pdf=render
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5
A Novel Nuclear Export Signal Sensitive to Oxidative Stress in the Fission Yeast Transcription Factor Pap1
Autor: Minoru Yoshida, Nobuaki Kudo, Takashi Toda, Sueharu Horinouchi, Hiroshi Taoka
Publikováno v: Journal of Biological Chemistry. 274:15151-15158
Pap1, a fission yeast AP-1-like transcription factor, is negatively regulated by CRM1/exportin 1, the nuclear export factor. Pap1 was localized normally in the cytoplasm but was accumulated in the nucleus when Crm1 was inactivated by a temperature-se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bcf43d248abcbd5cf37948b821a3909
https://doi.org/10.1074/jbc.274.21.15151
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6
Leptomycin, an antifungal and antitumor Streptomyces metabolite, is a novel chemical probe for eukaryotic nucleo-cytoplasmic transport
Autor: Minoru Yoshida, Shin Akakura, Sueharu Horinouchi, Nobuaki Kudo, Hiroshi Taoka
Publikováno v: Actinomycetologica. 12:120-128
Leptomycin B (LMB) is a Streptomyces metabolite that causes specific inhibition of the cell cycle of yeast and mammalian cells. The target molecule of LMB in fission yeast has been shown by genetic analysis to be CRM1, a highly conserved protein in e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fb7b0d808491d9628949bd581a9e5d8
https://doi.org/10.3209/saj.12_120
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7
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region
Autor: Sueharu Horinouchi, Nobuaki Kudo, Barbara Wolff, Erwin P. Schreiner, Daisuke Fujiwara, Hiroshi Taoka, Minoru Yoshida, Nobuaki Matsumori
The cellular target of leptomycin B (LMB), a nuclear export inhibitor, has been identified as CRM1 (exportin 1), an evolutionarily conserved receptor for the nuclear export signal of proteins. However, the mechanism by which LMB inhibits CRM1 still r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7514eaef47cc12011d3baa7947609f5e
https://europepmc.org/articles/PMC17741/
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