Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Hiroshi Shirasawa"'
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 5, Pp 1154-1159 (2019)
In Japan, routine immunization for polio using the oral polio vaccine (OPV) was suspended in September 2012; subsequently, an immunization program with inactivated polio vaccines (IPVs), the conventional IPV (cIPV) derived from virulent strains, and
Externí odkaz:
https://doaj.org/article/9cc571319afe465c8629c0f04f1295b4
Autor:
Reina Sasaki, Tatsuo Kanda, Masato Nakamura, Shingo Nakamoto, Yuki Haga, Shuang Wu, Hiroshi Shirasawa, Osamu Yokosuka
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146314 (2016)
The induction of apoptosis in hepatic stellate cells (HSCs) is a promising therapeutic strategy against hepatitis B virus (HBV)-related hepatic fibrosis. The underlying mechanisms of apoptosis in HSCs, however, are unknown under consideration of HBV
Externí odkaz:
https://doaj.org/article/5c2cedab52a446dd94929076c75a8d69
Autor:
Nan Nwe Win, Shingo Nakamoto, Myint Myint Sein, Mitsuhiko Moriyama, Tatsuo Kanda, Hiroshi Shirasawa
Publikováno v:
Diseases, Vol 6, Iss 1, p 3 (2017)
Myanmar is adjacent to India, Bangladesh, Thailand, Laos and China. In Myanmar, the prevalence of hepatitis B virus (HBV) infections is 6.5% and accounts for 60% of hepatocellular carcinoma. HBV has nine genotypes that have been identified by molecul
Externí odkaz:
https://doaj.org/article/8da112637aa642d2ad8acd7896d5539f
Autor:
Xia Jiang, Tatsuo Kanda, Shuang Wu, Shingo Nakamoto, Masato Nakamura, Reina Sasaki, Yuki Haga, Takaji Wakita, Hiroshi Shirasawa, Osamu Yokosuka
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131973 (2015)
Hepatitis C virus (HCV) infection is one of the major causes of cirrhosis and hepatocellular carcinoma. HCV nonstructural protein 5A (NS5A) is an attractive antiviral target and plays an important role in HCV replication as well as hepatocarcinogenes
Externí odkaz:
https://doaj.org/article/b128b88bc3de423fb0cefab82869bd47
Autor:
Xia Jiang, Tatsuo Kanda, Shuang Wu, Shingo Nakamoto, Kengo Saito, Hiroshi Shirasawa, Tomoko Kiyohara, Koji Ishii, Takaji Wakita, Hiroaki Okamoto, Osamu Yokosuka
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101993 (2014)
BACKGROUND:Despite the development and availability of hepatitis A virus (HAV) vaccine, HAV infection is still a major cause of acute hepatitis that occasionally leads to fatal liver disease. HAV internal ribosomal entry-site (IRES) is one of the att
Externí odkaz:
https://doaj.org/article/86b063edbcbb4524a52d1c12988e9ed0
Autor:
Xia Jiang, Tatsuo Kanda, Shuang Wu, Shingo Nakamoto, Takaji Wakita, Hiroshi Shirasawa, Osamu Yokosuka
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113499 (2014)
BACKGROUND:We previously reported that the hepatitis C virus (HCV) nonstructural protein 5A (NS5A) down-regulates TLR4 signaling and lipopolysaccharide-induced apoptosis of hepatocytes. There have been several reports regarding the association betwee
Externí odkaz:
https://doaj.org/article/50cd987916c44b1e8e098f9b3995dc6b
Publikováno v:
Microbiology and Immunology. 66:519-528
Lactate dehydrogenase (LDH) levels in measles virus (MeV) reinfection cases for the diagnosis of measles have not been extensively studied. Thus, we evaluated the significance of serum LDH in the immune response of patients with MeV reinfection in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10355e61689592dbbdb5b8a9fec72259
https://doi.org/10.1111/1348-0421.13021
https://doi.org/10.1111/1348-0421.13021
Autor:
Ruirong Yi, Akio Matsumoto, Kengo Saito, Yutaka Tamura, Ohno Yoshifumi, Hiroshi Shirasawa, Shoji Matsumoto, Akiko Suganami
Publikováno v:
Anticancer Research. 41:699-706
Background/aim Benzimidazoles are considered potential anticancer candidates. We herein studied the anticancer activity of CCL299, 4-(1H-1,3-benzodiazol-1-yl) benzonitrile. Materials and methods In this in vitro study, we used ATP assays, flow cytome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f85186406bd17220674cf43b0f87ce
https://doi.org/10.21873/anticanres.14821
https://doi.org/10.21873/anticanres.14821
Autor:
Qisen Li, Weiwei Chen, Shuhan Guo, Akiko Suganami, Shingo Nakamoto, Zheng Tian, Ohno Yoshifumi, Shinji Harada, Hiroshi Shirasawa, Naohisa Isegawa, Yutaka Tamura, Majid Vahed, Ruirong Yi, Kengo Saito, Keisuke Yoshida, Nan Nwe Win, Atsushi Nishida, Xue Ma
Publikováno v:
Oncology Reports. 44:2770-2782
Targeting cell‑cycle regulation to hinder cancer cell proliferation is a promising anticancer strategy. The present study investigated the effects of a novel sulfonamide, CCL113, on cell cycle progression in cancer cell lines (HeLa and HepG2), a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4082da294b96fb37db07ac4fc2c20afc
https://doi.org/10.3892/or.2020.7805
https://doi.org/10.3892/or.2020.7805
Autor:
Keita Terui, Yoshiharu Sato, Takeshi Saito, Ayako Takenouchi, Eriko Y Saito, Tadashi Matsunaga, Hideo Yoshida, Kengo Saito, Hiroshi Shirasawa, Tomoro Hishiki
Publikováno v:
Pediatric Surgery International
Purpose Oncolytic viral therapy for neuroblastoma (NB) cells with Sindbis virus (SINV) is a promising strategy for treating high-risk NB. Here, we evaluated the possibility of using SINV structural proteins as therapeutic agents for NB since UV-inact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde8f39093239e947d6a87d40b66f4f0
https://doi.org/10.1007/s00383-020-04719-8
https://doi.org/10.1007/s00383-020-04719-8