Zobrazeno 1 - 10
of 563
pro vyhledávání: '"Hiroshi Seno"'
Autor:
Kota Kujime, Hiroshi Seno, Kenzaburo Nakajima, Masatoshi Yamazaki, Ichiro Sakuma, Kenichiro Yamagata, Kengo Kusano, Naoki Tomii
Publikováno v:
Journal of Arrhythmia, Vol 40, Iss 4, Pp 948-957 (2024)
Abstract Background Predicting the origin of premature ventricular contraction (PVC) from the preoperative electrocardiogram (ECG) is important for catheter ablation therapies. We propose an explainable method that localizes PVC origin based on the s
Externí odkaz:
https://doaj.org/article/3a9e983ac40e47d5acda9ea591600b26
Autor:
Takafumi Yanaidani, MD, Tomoaki Matsumori, MD, PhD, Yuya Muramoto, MD, PhD, Yoshihiro Nishikawa, MD, PhD, Takahisa Maruno, MD, PhD, Masahiro Shiokawa, MD, PhD, Norimitsu Uza, MD, PhD, Hiroshi Seno, MD, PhD
Publikováno v:
VideoGIE, Vol 9, Iss 5, Pp 243-246 (2024)
Externí odkaz:
https://doaj.org/article/e5d27129152842b69e716bfc7b3bbac5
Autor:
Mayuki Omatsu, Yuki Nakanishi, Kosuke Iwane, Naoki Aoyama, Angeles Duran, Yu Muta, Anxo Martinez-Ordoñez, Qixiu Han, Nobukazu Agatsuma, Kenta Mizukoshi, Munenori Kawai, Go Yamakawa, Mio Namikawa, Kensuke Hamada, Yuichi Fukunaga, Takahiro Utsumi, Makoto Sono, Tomonori Masuda, Akitaka Hata, Osamu Araki, Munemasa Nagao, Takaaki Yoshikawa, Satoshi Ogawa, Yukiko Hiramatsu, Motoyuki Tsuda, Takahisa Maruno, Toshiaki Kogame, Hiroaki Kasashima, Nobuyuki Kakiuchi, Masahiro M. Nakagawa, Kenji Kawada, Masakazu Yashiro, Kiyoshi Maeda, Yasuyuki Saito, Takashi Matozaki, Akihisa Fukuda, Kenji Kabashima, Kazutaka Obama, Seishi Ogawa, Nader Sheibani, Maria T. Diaz-Meco, Jorge Moscat, Hiroshi Seno
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Mesenchymal activation, characterized by dense stromal infiltration of immune and mesenchymal cells, fuels the aggressiveness of colorectal cancers (CRC), driving progression and metastasis. Targetable molecules in the tumor microenvironment
Externí odkaz:
https://doaj.org/article/faf191500a2f4f9e8f8e32b58ac4ba14
Autor:
Tomonori Masuda, Akihisa Fukuda, Go Yamakawa, Mayuki Omatsu, Mio Namikawa, Makoto Sono, Yuichi Fukunaga, Munemasa Nagao, Osamu Araki, Takaaki Yoshikawa, Satoshi Ogawa, Kenji Masuo, Norihiro Goto, Yukiko Hiramatsu, Yu Muta, Motoyuki Tsuda, Takahisa Maruno, Yuki Nakanishi, Toshihiko Masui, Etsuro Hatano, Tomoko Matsuzaki, Makoto Noda, Hiroshi Seno
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 18 (2023)
RECK is downregulated in various human cancers; however, how RECK inactivation affects carcinogenesis remains unclear. We addressed this issue in a pancreatic ductal adenocarcinoma (PDAC) mouse model and found that pancreatic Reck deletion dramatical
Externí odkaz:
https://doaj.org/article/b38a98869dd34cd986aee1b4471bb6da
Autor:
Akio Umemoto, Takeshi Kuwada, Koichi Murata, Masahiro Shiokawa, Sakiko Ota, Yoshiki Murotani, Akihiro Itamoto, Kohei Nishitani, Hiroyuki Yoshitomi, Takayuki Fujii, Akira Onishi, Hideo Onizawa, Kosaku Murakami, Masao Tanaka, Hiromu Ito, Hiroshi Seno, Akio Morinobu, Shuichi Matsuda
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background Anti-citrullinated protein/peptide antibodies (ACPAs) are present in patients at onset and have important pathogenic roles during the course of rheumatoid arthritis (RA). The characteristics of several molecules recognized by ACPA
Externí odkaz:
https://doaj.org/article/bdd93818c9db4dcdbadf58d97cf95d82
Autor:
Hirokazu Sawamura, MD, Yasuyuki Onishi, MD, Tsuyoshi Ohno, MD, Tomoya Ikeda, MD, Shuji Yamamoto, MD, Hiroshi Seno, MD, Yuji Nakamoto, MD
Publikováno v:
Radiology Case Reports, Vol 17, Iss 10, Pp 3727-3730 (2022)
An 88-year-old woman with a history of multiple hepatocellular carcinomas (HCCs) presented with a new HCC in segment seven of the liver. We decided to perform transarterial chemoembolization for HCC. During treatment, the HCC was supplied by the righ
Externí odkaz:
https://doaj.org/article/ca15eb5c336c478793c58a0c3adb156b
Autor:
Soichi Arasawa, Haruhiko Takeda, Atsushi Takai, Eriko Iguchi, Yuji Eso, Takahiro Shimizu, Ken Takahashi, Taiki Yamashita, Yoshihide Ueda, Hiroyuki Marusawa, Hiroshi Seno
Publikováno v:
Hepatology Communications, Vol 7, Iss 3, Pp e0047-e0047 (2023)
Background. Although HBV infection is a serious health issue worldwide, the landscape of HBV genome dynamics in the host has not yet been clarified. This study aimed to determine the continuous genome sequence of each HBV clone using a single-molecul
Externí odkaz:
https://doaj.org/article/c0e6b6ac7c3d463491e6446b78800713
Autor:
Sadanori Watanabe, Akitada Yogo, Tsuguteru Otsubo, Hiroki Umehara, Jun Oishi, Toru Kodo, Toshihiko Masui, Shigeo Takaishi, Hiroshi Seno, Shinji Uemoto, Etsuro Hatano
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Pancreatic cancer is one of the most lethal tumors. The aim of this study is to provide an effective therapeutic discovery platform for pancreatic cancer by establishing and characterizing patient-derived organoids (PDOs). Methods
Externí odkaz:
https://doaj.org/article/efe91fea083e48c7aae1df225a63007e
Autor:
Fumiyasu Nakamura, Haruhiko Takeda, Yoshihide Ueda, Atsushi Takai, Ken Takahashi, Yuji Eso, Soichi Arasawa, Eriko Iguchi, Takahiro Shimizu, Masako Mishima, Ken Kumagai, Taiki Yamashita, Shinji Uemoto, Nobuyuki Kato, Hiroyuki Marusawa, Akihiro Sekine, Hiroshi Seno
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The emergence of hepatitis C virus (HCV) with resistance-associated substitution (RAS), produced by mutations in the HCV genome, is a major problem in direct acting antivirals (DAA) treatment. This study aimed to clarify the mutational spect
Externí odkaz:
https://doaj.org/article/526c65e7dd094316aad06e4b64ba4aa5
Autor:
Hirokazu Okada, Ken Takahashi, Hiroaki Yaku, Kouji Kobiyama, Keiko Iwaisako, Xiangdong Zhao, Masahiro Shiokawa, Norimitsu Uza, Yuzo Kodama, Ken J. Ishii, Hiroshi Seno
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Although checkpoint inhibitors (CPIs) have changed the paradigm of cancer therapy, low response rates and serious systemic adverse events remain challenging. In situ vaccine (ISV), intratumoral injection of immunomodulators that stimulate in
Externí odkaz:
https://doaj.org/article/12fbcc7326ec4f2aaa2b0349a2d4b50f