Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hiroshi Sakikawa"'
Autor:
Yoshikazu Haraguchi, and Takuya Furuta, Shinji Aki, Takafumi Fujioka, Masashi Ishigami, Hiroshi Sakikawa, Jun-ichi Minamikawa
Publikováno v:
Organic Process Research & Development. 5:535-538
The fluorenone derivative (OPC-34165) has potent repairing and protecting activities for peripheral and central nervous system degeneration. A synthesis of the biphenyl-2-carboxylic acid derivative, which is the key intermediate of OPC-34165, is desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb0c96f25072685ad369fd445c12a70f
https://doi.org/10.1021/op0001279
https://doi.org/10.1021/op0001279
Autor:
Masashi Ishigami, Jun-ichi Minamikawa, Takuya Furuta, Yoshikazu Haraguchi, Shinji Aki, Takafumi Fujioka, Hiroshi Sakikawa
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a63e8583a1782336a636e7babdce50d
https://doi.org/10.1002/chin.200209103
https://doi.org/10.1002/chin.200209103
Autor:
Sumitsugu Kisanuki, Haruo Takaku, Hiroshi Enomoto, Naoko Hattori, Satoru Misawa, Hideya Hayashi, Hiroshi Sakikawa, Shigeki Tanaka, Yoshiaki Kiso, Keisuke Terashima, Ryohei Kato, Satoshi Nojima, Makoto Shintani, Tsutomu Mimoto, Tominaga Fukazawa, Junya Imai, Takamasa Ueno
Publikováno v:
Chemicalpharmaceutical bulletin. 48(9)
We designed and synthesized a new class of peptidomimetic human immunodeficiency virus protease inhibitors containing a unique unnatural amino acid, allophenylnorstatine [Apns; (2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid], with a hydroxymethylcarb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c861d67f408ac343dcdc49e715a5711b
https://pubmed.ncbi.nlm.nih.gov/10993230
https://pubmed.ncbi.nlm.nih.gov/10993230
Publikováno v:
Chemical and Pharmaceutical Bulletin. 38:270-272
We have developed an efficient method for solid phase peptide synthesis which consists of N α -selective deprotection by dilute methanesulfonic acid, in situ neutralization, and rapid coupling reaction using benzotriazol-1-yl-oxy-tris(dimethylamino)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0906515fa09bbb2b84e83cd70fb5b110
https://doi.org/10.1248/cpb.38.270
https://doi.org/10.1248/cpb.38.270
Autor:
Sumitsugu Kisanuki, Tooru Kimura, Yoshiaki Kiso, Hiroshi Enomoto, Hiroshi Sakikawa, Osamu Takahashi, Ryohei Katoh, Shigeki Tanaka, Junya Imai, Tsutomu Mimoto, Naoko Hattori, Kenichi Akaji
Publikováno v:
Peptide Chemistry 1992 ISBN: 9789401046480
Peptide Chemistry 1992
Peptide Chemistry 1992
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f3d64da198f5acc55fb97284fd05968
https://doi.org/10.1007/978-94-011-1474-5_130
https://doi.org/10.1007/978-94-011-1474-5_130
Autor:
Osamu Takahashi, Hideya Hayashi, Yoshiaki Kiso, Kenichi Akaji, Shigeki Tanaka, Hiroshi Sakikawa, Yuichi Nagano, Naoko Hattori, Sumitsugu Kisanuki, Tsutomu Mimoto, Makoto Shintani, Junya Imai
Publikováno v:
Chemicalpharmaceutical bulletin. 39(9)
A novel class of HIV-1 protease inhibitors containing a hydroxymethylcarbonyl (HMC) isostere were designed from the substrate transition state and synthesized. Phenylnorstatine [Pns; (2R,3S)-3-amino-2-hydroxy-4-phenylbutyric acid] and the 2S diastere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15e02eef31a0d335f9fd9cd2633e4c0
https://pubmed.ncbi.nlm.nih.gov/1804562
https://pubmed.ncbi.nlm.nih.gov/1804562