Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Hiroshi Sakagam"'
Autor:
Yosuke Iijima DDS, PhD, Miki Yamada DDS, Mai Amano MS, Saya Watanabe MS, Miki Fujimaru BS, Ayako Uematsu BS, Shunsuke Hino DDS, PhD, Motohiko Sano PhD, Norio Horie DDS, PhD, Hiroshi Sakagami PhD, Takahiro Kaneko DDS, PhD
Publikováno v:
Gerontology and Geriatric Medicine, Vol 10 (2024)
Purpose: Medication-related osteonecrosis of the jaw (MRONJ) caused by bisphosphonates (BPs) and denosumab (Dmab) is still a major oral adverse event caused by cancer treatment and may be under-recognized by private dental services. With the aim of r
Externí odkaz:
https://doaj.org/article/cea197e083464948a9fbe69e5cd66c95
Autor:
Ahmed Abdullah Al Awadh, Hiroshi Sakagami, Shigeru Amano, Ahmed M. Sayed, Mohamed E. Abouelela, Abdulaziz Hassan Alhasaniah, Nayef Aldabaan, Mohamed S. Refaey, Reda A. Abdelhamid, Heba M. A. Khalil, Dalia I. Hamdan, El-Shaymaa Abdel-Sattar, Mohamed A. A. Orabi
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Oral cancer is a severe health problem that accounts for an alarmingly high number of fatalities worldwide. Withania somnifera (L.) Dunal has been extensively studied against various tumor cell lines from different body organs, rarely from the oral c
Externí odkaz:
https://doaj.org/article/a343aed0edeb4855b2fa39f2ce8ce97a
Autor:
Hiroshi Sakagami
Publikováno v:
Medicines, Vol 11, Iss 5, p 11 (2024)
The journal Medicines (ISSN 2305-6320) was launched in 2014 [...]
Externí odkaz:
https://doaj.org/article/a9bdd1a6eeea4d3a8fd9fe1ecfa2f43f
Autor:
Swagatika Das, Praveen K. Roayapalley, Hiroshi Sakagami, Naoki Umemura, Dennis K. J. Gorecki, Mohammad Hossain, Masami Kawase, Umashankar Das, Jonathan R. Dimmock
Publikováno v:
Medicines, Vol 11, Iss 1, p 3 (2024)
Background: The objective of this study is to find novel antineoplastic agents that display greater toxicity to malignant cells than to neoplasms. In addition, the mechanisms of action of representative compounds are sought. This report describes the
Externí odkaz:
https://doaj.org/article/cddb50e03a91435d8ae782c624968b3c
Autor:
Ryuichiro Suzuki, Yoshiaki Shirataki, Akito Tomomura, Kenjiro Bandow, Hiroshi Sakagami, Mineko Tomomura
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17479 (2023)
Plants contain a large number of small-molecule compounds that are useful for targeting human health and in drug discovery. Healthy bone metabolism depends on the balance between bone-forming osteoblast activity and bone-resorbing osteoclast activity
Externí odkaz:
https://doaj.org/article/9687e507a90748cab31de01442d0f187
Autor:
Mohamed A. A. Orabi, Esam A. Orabi, Ahmed Abdullah Al Awadh, Mohammed Merae Alshahrani, Basel A. Abdel-Wahab, Hiroshi Sakagami, Tsutomu Hatano
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 1951 (2023)
Polyphenols have a variety of phenolic hydroxyl and carbonyl functionalities that enable them to scavenge many oxidants, thereby preserving the human redox balance and preventing a number of oxidative stress-related chronic degenerative diseases. In
Externí odkaz:
https://doaj.org/article/d23374b197684070869280133704aba7
Autor:
Ignacio Jimenez-Bueno, Rene Garcia-Contreras, Benjamin Aranda-Herrera, Hiroshi Sakagami, Christian Andrea Lopez-Ayuso, Hiroshi Nakajima, Carlos A. Jurado, Hamid Nurrohman
Publikováno v:
Biomimetics, Vol 8, Iss 7, p 514 (2023)
Assessing the biocompatibility of endodontic root-end filling materials through cell line responses is both essential and of utmost importance. This study aimed to the cytotoxicity of the type of cell death through apoptosis and autophagy, and odonto
Externí odkaz:
https://doaj.org/article/b09aac4dfffc4f1185e1cc9b4b2a93a2
Autor:
Tomoyuki Abe, Hiroshi Sakagami, Shigeru Amano, Shin Uota, Kenjiro Bandow, Yoshihiro Uesawa, Shiori U, Hiroki Shibata, Yuri Takemura, Yu Kimura, Koichi Takao, Yoshiaki Sugita, Akira Sato, Sei-ichi Tanuma, Hiroshi Takeshima
Publikováno v:
Medicines, Vol 10, Iss 7, p 43 (2023)
Background. Many anti-cancer drugs used in clinical practice cause adverse events such as oral mucositis, neurotoxicity, and extravascular leakage. We have reported that two 3-styrylchromone derivatives, 7-methoxy-3-[(1E)-2-phenylethenyl]-4H-1-benzop
Externí odkaz:
https://doaj.org/article/31dc0e9c3dec488e805ec9ceba69031b
Autor:
Aruna Chhikara, Praveen K. Roayapalley, Hiroshi Sakagami, Shigeru Amano, Keitaro Satoh, Yoshihiro Uesawa, Umashankar Das, Swagatika Das, Edgar A. Borrego, Cristina D. Guerena, Clare R. Hernandez, Renato J. Aguilera, Jonathan R. Dimmock
Publikováno v:
Molecules, Vol 27, Iss 19, p 6718 (2022)
Two series of novel unsymmetrical 3,5-bis(benzylidene)-4 piperidones 2a–f and 3a–e were designed as candidate antineoplastic agents. These compounds display potent cytotoxicity towards two colon cancers, as well as several oral squamous cell carc
Externí odkaz:
https://doaj.org/article/2a31bd5df66d4cda8c251e729ecf8583
Autor:
Li-Min Zhu, Hai-Xia Shi, Masahiro Sugimoto, Kenjiro Bandow, Hiroshi Sakagami, Shigeru Amano, Hai-Bin Deng, Qing-Yu Ye, Yun Gai, Xiao-Li Xin, Zhen-Ye Xu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Feiyanning formula (FYN) is a traditional Chinese medicine (TCM) prescription used for more than 20 years in the treatment of lung cancer. FYN is composed of Astragalus membranaceus, Polygonatum sibiricum, Atractylodes macrocephala, Cornus officinali
Externí odkaz:
https://doaj.org/article/95dab34c439544b0b8c04a9bf7271c98