Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hiroshi Nagasue"'
Autor:
Keita Arakawa, Kazunari Nakao, Shoji Furusako, Noboru Chida, Shunsuke Maehara, Kotaro Hoshida, Hiroshi Nagasue
Publikováno v:
European journal of pharmacology. 811
Recently, we identified a novel phosphodiesterase 2A (PDE2A) inhibitor, PDM-631 ((S)-3-cyclopropyl-6-methyl-1-(1-(4-(trifluoromethoxy)phenyl)propan-2-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one). PDM-631 showed potent inhibitory activities for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24eb375a9461c0fe7e1de58672e3651
https://pubmed.ncbi.nlm.nih.gov/28587776
https://pubmed.ncbi.nlm.nih.gov/28587776
Autor:
Harold B. Wood, Shunsuke Shimada, Hiroshi Nagasue, Takashi Mizuno, Tomokazu Hirabayashi, Toshiya Endo, Shigeki Matsumoto, Yutaka Kato, Shoji Furusako, Katsuyoshi Hikita, Ting Zhang, Keiko Taguchi, Yoshitaka Maeda, Kazunari Nakao, Alan Hruza, Paul Reichert, Isao Sakurada, Teruyuki Nishimura, Tooru Yokoyama, Yoshitaka Hosaka, Mikihiko Shinozaki, Katsutoshi Takeuchi
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(11)
Using structure based drug design, novel aminobenzisoxazoles as coagulation factor IXa inhibitors were designed and synthesized. Highly selective inhibition of FIXa over FXa was demonstrated. Anticoagulation profile of selected compounds was evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eacba671268d284c0b15e929dbcd5d6
https://pubmed.ncbi.nlm.nih.gov/28408226
https://pubmed.ncbi.nlm.nih.gov/28408226
Autor:
Isamu Shiina, Hiroshi Nagasue
Publikováno v:
Tetrahedron Letters. 43:5837-5840
A novel [1,3] sigmatropic rearrangement of ketene silyl acetals derived from benzyl α-substituted propanoates is developed. The reaction of ketene silyl acetal derived from optically active 1-phenylethyl 2-methylpropanoate mainly proceeds with the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e26f7597cb6d0ea91342321101559a0
https://doi.org/10.1016/s0040-4039(02)01168-1
https://doi.org/10.1016/s0040-4039(02)01168-1
Autor:
Hiroshi Nagasue, Isamu Shiina
Publikováno v:
ChemInform. 33
A novel [1,3] sigmatropic rearrangement of ketene silyl acetals derived from benzyl α-substituted propanoates is developed. The reaction of ketene silyl acetal derived from optically active 1-phenylethyl 2-methylpropanoate mainly proceeds with the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c473a275030d4fa796e783ac667ce88
https://doi.org/10.1002/chin.200247068
https://doi.org/10.1002/chin.200247068